The role of BMP4 in adipose-derived stem cell differentiation: A minireview
Frontiers in Cell and Developmental Biology, 2022 Bone morphogenetic protein 4 (BMP4) is a member of the transforming growth factor beta (TGF-β) superfamily of cytokines responsible for stem cells’ commitment to differentiation, proliferation, and maturation.
Abdul Malik Setiawan +3 more
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Enhanced in vivo osteogenesis by nanocarrier-fused bone morphogenetic protein-4 [PDF]
International Journal of Nanomedicine, 2013 Yasuyuki Shiozaki,1,2 Takashi Kitajima,4 Tetsuro Mazaki,1,2 Aki Yoshida,1 Masato Tanaka,1 Akihiro Umezawa,5 Mariko Nakamura,6 Yasuhiro Yoshida,3 Yoshihiro Ito,4 Toshifumi Ozaki,1 Akihiro Matsukawa2 1Department of Orthopedic Surgery, Okayama University ...
Shiozaki Y +10 more
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Comprehensive analyses of single-cell and bulk RNA-seq reveal the biological and prognostic roles of BMP4 in pancreatic adenocarcinoma [PDF]
Frontiers in Molecular BiosciencesBone Morphogenetic Protein 4 (BMP4) plays a critical role in development, but its function in pancreatic adenocarcinoma (PAAD) is not well understood.
Ao Wang +11 more
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BMP4 dose dictates lineage specification bias in human periodontal ligament stem cells [PDF]
Frontiers in Bioengineering and BiotechnologyIntroductionPeriodontal ligament stem cells (PDLSCs) represent a promising therapeutic cell source for regenerating periodontal tissues impaired by disease.
Yihong Li +9 more
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BMP4 Cross-talks With Estrogen/ERα Signaling to Regulate Adiposity and Glucose Metabolism in Females
EBioMedicine, 2016 Similar to estrogens, bone morphogenetic protein 4 (BMP4) promotes the accumulation of more metabolically active subcutaneous fat and reduction of visceral fat.
Jue Wang, Xi Li, Hai-Yan Huang
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Differentiation of human endometrial stem cells encapsulated in alginate hydrogel into oocyte-like cells [PDF]
BioImpacts, 2023 Introduction: Human endometrial mesenchymal stem cells (hEnMSCs) are a rich source of mesenchymal stem cells (MSCs) with multi-lineage differentiation potential, making them an intriguing tool in regenerative medicine, particularly for the treatment of ...
Diba Ghasemi +10 more
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Small molecule-induced destabilization of β-catenin and RAS is the ideal strategies for suppressing colorectal cancer [PDF]
Organoid, 2023 Background Mutations of adenomatous polyposis coli (APC) and KRAS play essential roles in the development of colorectal cancer (CRC) by forming an abnormal colon morphology.
Yonghyo Kim +3 more
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Expression of BMP-4 in dentigerous cyst and ameloblastoma: Is it a differentiation measure?
European Oral Research, 2022 Purpose: This study aimed to determine the expression of Bone Morphogenic Protein-4 (BMP 4) in dentigerous cyst (DC), unicystic-ameloblastoma (UA), and Multicystic-ameloblastoma (MA), and assess whether this marker can be a differentiation measure ...
Soudabeh Sargolzaei +2 more
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Effects of Treatment with Bone Morphogenetic Protein 4 and Co-culture on Expression of Piwil2 Gene in Mouse Differentiated Embryonic Stem Cells [PDF]
International Journal of Fertility and Sterility, 2009 Background Specific growth factors and feeder layers seem to have important roles in in vitro embryonic stem cells (ESCs) differentiation. In this study,the effects of bone morphogenetic protein 4 (BMP4) and mouse embryonic fibroblasts (MEFs) co-culture ...
Zohreh Makoolati +2 more
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BMP-treated human embryonic stem cells transcriptionally resemble amnion cells in the monkey embryo
Biology Open, 2021 Human embryonic stem cells (hESCs) possess an immense potential to generate clinically relevant cell types and unveil mechanisms underlying early human development.
Sapna Chhabra, Aryeh Warmflash
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