Results 31 to 40 of about 52,292 (275)

Fam20C Regulates Bone Resorption and Breast Cancer Bone Metastasis through Osteopontin and BMP4

Cancer Research, 2021
Osteoclastogenesis and bone metastasis are suppressed by myeloid-derived Fam20C, but enhanced by breast cancer-associated Fam20C, uncovering novel Fam20C functions and new therapeutic strategies via targeting Fam20C substrates OPN and BMP4.
Hao Zuo, Dengbao Yang, Y. Wan
semanticscholar   +1 more source

BMP4 (bone morphogenetic protein 4) [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2013
Review on BMP4 (bone morphogenetic protein 4), with data on DNA, on the protein encoded, and where the gene is implicated.
Thériault, BL, Nachtigal, MW
openaire   +2 more sources

Shear Stress Alterations Activate BMP4/pSMAD5 Signaling and Induce Endothelial Mesenchymal Transition in Varicose Veins

Cells, 2021
Chronic venous diseases, including varicose veins, are characterized by hemodynamic disturbances due to valve defects, venous insufficiency, and orthostatism.
Karthika Chandran Latha, Ahalya Sreekumar, V. Beena, Binil Raj S.S., Ravikumar B. Lakkappa, Ravi Kalyani, Radhakrishnan Nair, S. R. Kalpana, C. Kartha, Sumi Surendran   +9 more
semanticscholar   +1 more source

Modeling human trophoblast, the placental epithelium at the maternal fetal interface. [PDF]

, 2020
Appropriate human trophoblast lineage specification and differentiation is crucial for the establishment of normal placentation and maintenance of pregnancy. However, due to the lack of proper modeling systems, the molecular mechanisms of these processes
Bui, Tony, Horii, Mariko, Parast, Mana M, Touma, Ojeni   +3 more
core   +1 more source

Effect of fibronectin, FGF-2, and BMP4 in the stemness maintenance of BMSCs and the metabolic and proteomic cues involved

Stem cell research & therapeutics, 2021
Growing evidence suggests that the pluripotent state of mesenchymal stem cells (MSCs) relies on specific local microenvironmental cues such as adhesion molecules and growth factors.
Lingling Chen, Morgan Carlton, Xiao-dan Chen, N. Kaur, Hollie Ryan, T. Parker, Zhengmei Lin, Yin Xiao, Yinghong Zhou   +8 more
semanticscholar   +1 more source

BMP4, a new prognostic factor for glioma [PDF]

World Journal of Surgical Oncology, 2013
The expression status of bone morphogenetic protein 4 (BMP4) in gliomas is still unclear by now. We try to investigate the relationship between BMP4 expression and the biological behavior of gliomas in order to lay a foundation for the management of these tumors.A total of 630 patients with glioma were enrolled in the study from January 2002 to January
Wu, Qiang, Yao, Jiarui
openaire   +2 more sources

TGFβ/cyclin D1/Smad-mediated inhibition of BMP4 promotes breast cancer stem cell self-renewal activity

Oncogenesis, 2021
Basal-like triple-negative breast cancers (TNBCs) display poor prognosis, have a high risk of tumor recurrence, and exhibit high resistance to drug treatments.
Gang Yan, Meiou Dai, Chenjing Zhang, Sophie Poulet, Alaa Moamer, Ni Wang, Julien Boudreault, Suhad Ali, J. Lebrun   +8 more
semanticscholar   +1 more source

Specific Preferences in Lineage Choice and Phenotypic Plasticity of Glioma Stem Cells Under BMP4 and Noggin Influence [PDF]

, 2015
Although BMP4-induced differentiation of glioma stem cells (GSCs) is well recognized, details of the cellular responses triggered by this morphogen are still poorly defined.
Arakaki, Naomi, Fernandez Espinosa, Damian Dario, Garcia, Carolina Paola, Martinetto, Horacio Enrique, Miriuka, Santiago Gabriel, Roisman, Alejandro, Romorini, Leonardo, Scassa, Maria Elida, Sevlever, Gustavo Emilio, Slavutsky, Irma Rosa, Videla Richardson, Guillermo Agustín   +10 more
core   +1 more source

BMP4 micro‐immunotherapy increases collagen deposition and reduces PGE2 release in human gingival fibroblasts and increases tissue viability of engineered 3D gingiva under inflammatory conditions

The Journal of Periodontology, 2021
Background We aimed to evaluate the effect of low doses (LD) bone morphogenetic protein‐2 (BMP2) and BMP4 micro‐immunotherapy (MI) in two in vitro models of periodontal wound healing/regeneration.
Maria del Mar Ferrà-Cañellas, Marta Munar-Bestard, Laura Garcia-Sureda, B. Lejeune, J. M. Ramis, M. Monjo   +5 more
semanticscholar   +1 more source

Methanol and isopropanol embryo dosage response curves for wild-type and ethanol-sensitive zebrafish [PDF]

, 2016
It is well established that ethanol has an array of negative effects on developing embryos, from craniofacial abnormalities to cognitive deficits and behavioral disorders.
Anderson, Ashley
core   +1 more source