Results 41 to 50 of about 46,344 (243)
Hypoxia regulates BMP4 expression in the murine spleen during the recovery from acute anemia. [PDF]
PLoS ONE, 2010 Bone marrow erythropoiesis is primarily homeostatic, producing new erythrocytes at a constant rate. However at times of acute anemia, new erythrocytes must be rapidly produced much faster than bone marrow steady state erythropoiesis.
Dai-Chen Wu, Robert F Paulson
doaj +1 more source
Accumulation of rare coding variants in genes implicated in risk of human cleft lip with or without cleft palate. [PDF]
, 2019 Cleft lip with/without cleft palate (CLP) is a common craniofacial malformation with complex etiologies, reflecting both genetic and environmental factors. Most of the suspected genetic risk for CLP has yet to be identified. To further classify risk loci
Asrani, Kripa +4 more
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Current perspectives of the signaling pathways directing neural crest induction. [PDF]
, 2012 The neural crest is a migratory population of embryonic cells with a tremendous potential to differentiate and contribute to nearly every organ system in the adult body.
García-Castro, Martín I +1 more
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Noggin regulates Bmp4 activity during pituitary induction
Developmental Biology, 2007 Bone morphogenetic protein (Bmp) signaling is critical for the development and patterning of the mouse pituitary from the initial induction of Rathke's pouch to cell specification in the anterior lobe. We examined the regulation of Bmp signaling during pituitary development by analyzing null embryos for noggin, a Bmp 2 and 4 antagonist.
Davis, Shannon W., Camper, Sally A.
openaire +2 more sources
The Generation Of Novelty: The Province Of Developmental Biology [PDF]
, 2006 A response to Michael Ruse\u27s Forty Years A Philosopher Of Biology: Why EvoDevo Makes Me Still Excited About My Subject
Gilbert, Scott F.
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BMP4 expression in the developing rat retina
Brain Research, 2006 We investigated the expression of bone morphogenetic protein-4 (BMP4) in the developing retina. At E19, we found very intense BMP4 immunoreactivity (IR) in the nerve fiber layer. At P1, the inner plexiform layer exhibited very strong BMP4-IR. Thereafter, abundant BMP4 expression was kept to the adult period.
Yuka, Maruyama +3 more
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Mutations in BMP4 Cause Eye, Brain, and Digit Developmental Anomalies: Overlap between the BMP4 and Hedgehog Signaling Pathways [PDF]
The American Journal of Human Genetics, 2008 Developmental ocular malformations, including anophthalmia-microphthalmia (AM), are heterogeneous disorders with frequent sporadic or non-Mendelian inheritance. Recurrent interstitial deletions of 14q22-q23 have been associated with AM, sometimes with poly/syndactyly and hypopituitarism.
Bakrania, P. +20 more
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Journal of Experimental & Clinical Cancer Research, 2018 Background Autophagy is a conserved catabolic process with complicated roles in tumor development. Bone morphogenetic protein 4 (BMP4), a member of the transforming growth factor (TGF-β) family of regulatory proteins, plays a crucial role in human ...
Ganlu Deng +10 more
doaj +1 more source
BMP4 expression in the adult rat brain [PDF]
, 2006 Bone morphogenetic protein-4 (BMP4) is a member of the transforming growth factor β (TGF- β) superfamily and plays important roles in multiple biological events. Although BMP4 expression has been well described in the early development of central nervous
37 +5 more
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BMP4 regulates the hematopoietic stem cell niche
Blood, 2009 Abstract Bone morphogenetic protein 4 (BMP4) is required for mesoderm commitment to the hematopoietic lineage during early embryogenesis. However, deletion of BMP4 is early embryonically lethal and its functional role in definitive hematopoiesis is unknown.
Devorah C, Goldman +5 more
openaire +3 more sources