Results 51 to 60 of about 46,344 (243)

Bone morphogenetic protein 4 regulates immortalized chicken preadipocyte proliferation by promoting G1/S cell cycle progression

FEBS Open Bio, 2019
Bone morphogenetic protein 4 (BMP4) has been reported to regulate adipose development, but its role in preadipocyte proliferation has not been explored in vitro.
Hongyan Chen, Chang Liu, Chong Chen, Zhiyong Su, Jingting Shu, Ming Zhang, Hui Li, Bohan Cheng   +7 more
doaj   +1 more source

Antagonizing CD105 enhances radiation sensitivity in prostate cancer. [PDF]

, 2018
Radiation therapy is the primary intervention for nearly half of the patients with localized advanced prostate cancer and standard of care for recurrent disease following surgery.
Andres, Allen, Angara, Bryan, Bhowmick, Neil A, Duong, Frank, Gottlieb, Roberta, Haldar, Subhash, Liu, Zhenqiu, Madhav, Anisha, Mishra, Rajeev, Zumsteg, Zachary S   +9 more
core   +1 more source

Are physiological oscillations physiological?

The Journal of Physiology, EarlyView., 2023
Abstract figure legend Mechanisms and functions of physiological oscillations. Abstract Despite widespread and striking examples of physiological oscillations, their functional role is often unclear. Even glycolysis, the paradigm example of oscillatory biochemistry, has seen questions about its oscillatory function.
Lingyun (Ivy) Xiong, Alan Garfinkel
wiley   +1 more source

The level of BMP4 signaling is critical for the regulation of distinct T-box gene expression domains and growth along the dorso-ventral axis of the optic cup [PDF]

, 2006
Background: Polarised gene expression is thought to lead to the graded distribution of signaling molecules providing a patterning mechanism across the embryonic eye.
Behesti, H, Holt, JKL, Sowden, JC
core  

Simulations demonstrate a simple network to be sufficient to control branch point selection, smooth muscle and vasculature formation during lung branching morphogenesis [PDF]

, 2012
Proper lung functioning requires not only a correct structure of the conducting airway tree, but also the simultaneous development of smooth muscles and vasculature.
Cellière, Géraldine, Iber, Dagmar, Menshykau, Denis   +2 more
core   +3 more sources

Determining the function of nuclear Bmp4

The FASEB Journal, 2009
Bone morphogenetic protein 4 (Bmp4) is a well known growth factor that regulates gene expression through the SMAD signaling pathway. Bmp4 is involved in many developmental processes and has been identified as an important factor in several cancers, including melanoma, ovarian cancer, and colon cancer ...
Trina J Loos, Laura C Bridgewater
openaire   +1 more source

ETV2 Mediated Differentiation of Human Pluripotent Stem Cells Results in Functional Endothelial Cells for Engineering Advanced Vascularized Microphysiological Models

Advanced Healthcare Materials, EarlyView.
A robust method to generate functional human iPSC‐derived endothelial cells using inducible ETV2 expression. These cells self‐organize into stable, lumenized microvascular networks within microfluidic chips, surpassing conventional differentiation methods.
Shun Zhang, Zhengpeng Wan, Lei Wang, Caihong Wu, Junkai Zhang, Sarah Spitz, Xun Wang, Marie A. Floryan, Mark F. Coughlin, Francesca M. Pramotton, Liling Xu, Ron Weiss, Roger D. Kamm   +12 more
wiley   +1 more source

BMP4 Signaling Is Able to Induce an Epithelial-Mesenchymal Transition-Like Phenotype in Barrett's Esophagus and Esophageal Adenocarcinoma through Induction of SNAIL2.

PLoS ONE, 2016
BackgroundBone morphogenetic protein 4 (BMP4) signaling is involved in the development of Barrett's esophagus (BE), a precursor of esophageal adenocarcinoma (EAC).
Christine Kestens, Peter D Siersema, G Johan A Offerhaus, Jantine W P M van Baal   +3 more
doaj   +1 more source

BMP suppresses WNT to integrate patterning of orthogonal body axes in adult planarians.

PLoS Genetics, 2023
Adult regeneration restores patterning of orthogonal body axes after damage in a post-embryonic context. Planarians regenerate using distinct body-wide signals primarily regulating each axis dimension: anteroposterior Wnts, dorsoventral BMP, and ...
Eleanor G Clark, Christian P Petersen
doaj   +1 more source

BMP4 Regulates Pancreatic Progenitor Cell Expansion through Id2 [PDF]

Journal of Biological Chemistry, 2006
Inhibitor of DNA binding (Id) proteins bind to and inhibit the function of basic helix-loop-helix (bHLH) transcription factors including those that regulate pancreatic development. Moreover, bone morphogenetic proteins (BMPs) regulate the expression of Ids.
Hong, Hua, You-Qing, Zhang, Sandrine, Dabernat, Marcie, Kritzik, Daisy, Dietz, Lori, Sterling, Nora, Sarvetnick   +6 more
openaire   +2 more sources