Results 71 to 80 of about 52,292 (275)

Branch Mode Selection during Early Lung Development [PDF]

, 2012
Many organs of higher organisms, such as the vascular system, lung, kidney, pancreas, liver and glands, are heavily branched structures. The branching process during lung development has been studied in great detail and is remarkably stereotyped.
A Kicheva, A Weddemann, A White, AA Mailleux, AC White, AD Bragg, AJ Bard, B Hebert, B West, B Xu, BA Hyatt, BA Hyatt, C Chiang, C Nelson, Conradin Kraemer, CV Pepicelli, D Hartmann, D Hartmann, D Lebeche, D Warburton, Dagmar Iber, Denis Menshykau, E Crampin, E Domyan, E Weibel, Edmund J. Crampin, G Carraro, H Kitaoka, H Kitaoka, H Min, IJ Cutress, IV Nesmelova, J Maina, J Motoyama, J Murray, J Ries, J Sharpe, JA Goetz, JC Clark, K Sekine, KA Moore, KM Short, LAD Miller, LL Abler, LV Goodrich, M Affolter, M Carin, M Kumar, M Unbekandt, M Weaver, M Weaver, MC Eblaghie, MC Eblaghie, N Gjorevski, N Kim, P Chuang, P Nyeng, PM Lewis, R Aris, R Vuilleumier, RJ Metzger, RJ Metzger, RS Moura, RW Glenny, S Bellusci, S Bellusci, S Bellusci, S Bellusci, S Kondo, S Lubkin, S Lubkin, S Malpel, SK Ramasamy, SR Yu, T Bollenbach, T Hirashima, T Miura, T Miura, T Nelson, T Okubo, T Wilson, TM Moore, TR Nelson, U Frey, V Thummler, W Cardoso, WV Cardoso, X Wan, Y Litingtung   +88 more
core   +6 more sources

BMP4 regulates the hematopoietic stem cell niche

Blood, 2009
Abstract Bone morphogenetic protein 4 (BMP4) is required for mesoderm commitment to the hematopoietic lineage during early embryogenesis. However, deletion of BMP4 is early embryonically lethal and its functional role in definitive hematopoiesis is unknown.
Devorah C, Goldman, Alexis S, Bailey, Dana L, Pfaffle, Azzah, Al Masri, Jan L, Christian, William H, Fleming   +5 more
openaire   +3 more sources

Antagonizing CD105 enhances radiation sensitivity in prostate cancer. [PDF]

, 2018
Radiation therapy is the primary intervention for nearly half of the patients with localized advanced prostate cancer and standard of care for recurrent disease following surgery.
Andres, Allen, Angara, Bryan, Bhowmick, Neil A, Duong, Frank, Gottlieb, Roberta, Haldar, Subhash, Liu, Zhenqiu, Madhav, Anisha, Mishra, Rajeev, Zumsteg, Zachary S   +9 more
core   +1 more source

BMP4 Cross-talks With Estrogen/ERα Signaling to Regulate Adiposity and Glucose Metabolism in Females

EBioMedicine, 2016
Similar to estrogens, bone morphogenetic protein 4 (BMP4) promotes the accumulation of more metabolically active subcutaneous fat and reduction of visceral fat.
Shu-wen Qian, Yan Liu, Jue Wang, Ji-Chan Nie, Meng-yuan Wu, Yan Tang, Ya-Xin Zhao, Xi Li, Hai-yan Huang, Liang Guo, Xi-shi Liu, Cong-jian Xu, Qi-qun Tang   +12 more
doaj   +1 more source

BMP4 expression in the adult rat brain [PDF]

, 2006
Bone morphogenetic protein-4 (BMP4) is a member of the transforming growth factor β (TGF- β) superfamily and plays important roles in multiple biological events. Although BMP4 expression has been well described in the early development of central nervous
37, 38, 39, Mikawa, Sumiko, Sato, Kohji, Wang, Cong   +5 more
core   +2 more sources

Inhibition of EZH2 Promotes Human Embryonic Stem Cell Differentiation into Mesoderm by Reducing H3K27me3. [PDF]

, 2017
Mesoderm derived from human embryonic stem cells (hESCs) is a major source of the mesenchymal stem/stromal cells (MSCs) that can differentiate into osteoblasts and chondrocytes for tissue regeneration.
Aghaloo, Tara, Deng, Peng, Hong, Christine, Szymanski, John M, Wang, Cun-Yu, Yu, Bo, Yu, Yongxin   +6 more
core   +5 more sources

Potential Role of Circulating Endoglin in Hypertension via the Upregulated Expression of BMP4

Cells, 2020
Endoglin is a membrane glycoprotein primarily expressed by the vascular endothelium and involved in cardiovascular diseases. Upon the proteolytic processing of the membrane-bound protein, a circulating form of endoglin (soluble endoglin, sEng) can be ...
Eunate Gallardo-Vara, Luis Gamella-Pozuelo, L. Pérez-Roque, J. Bartha, Irene García‐Palmero, J. Casal, J. López-Novoa, M. Pericacho, C. Bernabéu   +8 more
semanticscholar   +1 more source

BMP4 Signaling Is Able to Induce an Epithelial-Mesenchymal Transition-Like Phenotype in Barrett's Esophagus and Esophageal Adenocarcinoma through Induction of SNAIL2.

PLoS ONE, 2016
BackgroundBone morphogenetic protein 4 (BMP4) signaling is involved in the development of Barrett's esophagus (BE), a precursor of esophageal adenocarcinoma (EAC).
Christine Kestens, Peter D Siersema, G Johan A Offerhaus, Jantine W P M van Baal   +3 more
doaj   +1 more source

Notch signaling-mediated osteocytic overexpression of BMP4 promotes osteogenic differentiation of bone marrow stromal cells

Di-san junyi daxue xuebao, 2021
Objective To investigate the effect of bone morphogenetic protein 4 (BMP4) overexpression in MLO-Y4 osteocytes on osteogenic differentiation of bone marrow stromal ST2 cells through Notch signaling. Methods Ad-GFP or Ad-BMP4 infected MLO-Y4 cells were co-
XIE Zhengsong, ZHAO Yixin, LYU Ziling, LIU Hong, TU Xiaolin   +4 more
doaj   +1 more source

The level of BMP4 signaling is critical for the regulation of distinct T-box gene expression domains and growth along the dorso-ventral axis of the optic cup [PDF]

, 2006
Background: Polarised gene expression is thought to lead to the graded distribution of signaling molecules providing a patterning mechanism across the embryonic eye.
Behesti, H, Holt, JKL, Sowden, JC
core