Results 41 to 50 of about 115,318 (308)
Digit patterning during limb development as a result of the BMP-receptor interaction [PDF]
, 2012 Turing models have been proposed to explain the emergence of digits during limb development. However, so far the molecular components that would give rise to Turing patterns are elusive.
Badugu, Amarendra +4 more
core +2 more sources
Hemojuvelin-Neogenin Interaction Is Required for Bone Morphogenic Protein-4-induced Hepcidin Expression [PDF]
, 2009 Hemojuvelin (HJV) is a glycosylphosphatidylinositol-linked protein and binds both bone morphogenic proteins (BMPs) and neogenin. Cellular HJV acts as a BMP co-receptor to enhance the transcription of hepcidin, a key iron regulatory hormone secreted ...
An-Sheng Zhang +44 more
core +4 more sources
BMP signaling and early embryonic patterning [PDF]
Cytokine & Growth Factor Reviews, 2005 Bone morphogenetic proteins (BMPs) play pleiotropic roles during embryonic development as well as throughout life. Recent genetic approaches especially using the mouse gene knockout system revealed that BMP signaling is greatly involved in early embryonic patterning, which is a dynamic event to establish three-dimensional polarities.
Satoshi, Kishigami, Yuji, Mishina
openaire +2 more sources
Smad-Independent BMP Signaling in Somatic Cells Limits the Size of the Germline Stem Cell Pool
Stem Cell Reports, 2018 Summary: In developing organisms, proper tuning of the number of stem cells within a niche is critical for the maintenance of adult tissues; however, the involved mechanisms remain largely unclear.
Chen-Yuan Tseng +9 more
doaj +1 more source
Bone Research, 2022 Spondylocarpotarsal syndrome (SCT) is a rare musculoskeletal disorder characterized by short stature and vertebral, carpal, and tarsal fusions resulting from biallelic nonsense mutations in the gene encoding filamin B (FLNB).
Jennifer Zieba +8 more
doaj +1 more source
Molecular mechanisms of neural crest formation [PDF]
, 1999 The neural crest is a transient population of multipotent precursor cells named for its site of origin at the crest of the closing neural folds in vertebrate embryos.
Bronner-Fraser, Marianne +1 more
core +1 more source
Regulation of the BMP Signaling-Responsive Transcriptional Network in the Drosophila Embryo.
PLoS Genetics, 2016 The BMP signaling pathway has a conserved role in dorsal-ventral axis patterning during embryonic development. In Drosophila, graded BMP signaling is transduced by the Mad transcription factor and opposed by the Brinker repressor.
Lisa Deignan +7 more
doaj +1 more source
Current perspectives of the signaling pathways directing neural crest induction. [PDF]
, 2012 The neural crest is a migratory population of embryonic cells with a tremendous potential to differentiate and contribute to nearly every organ system in the adult body.
García-Castro, Martín I +1 more
core +2 more sources
Wnt Signaling in Neural Crest Ontogenesis and Oncogenesis. [PDF]
, 2019 Neural crest (NC) cells are a temporary population of multipotent stem cells that generate a diverse array of cell types, including craniofacial bone and cartilage, smooth muscle cells, melanocytes, and peripheral neurons and glia during embryonic ...
Hao, Hongyan +4 more
core +2 more sources
Stem Cells: Keeping BMP Signaling Local [PDF]
Current Biology, 2011 In stem cell niches, the spatial extent of growth factor signaling needs to be tightly controlled. A new study on the Drosophila testicular germline stem cell niche has revealed that BMP signaling is locally activated through linkage to adherens junctions.
Ma, Xing, Xie, Ting
openaire +3 more sources