Results 41 to 50 of about 905,740 (294)

Assessment of BMP responses in an in vitro model of acute ethanol toxicity

MethodsX, 2022
The assay presented here was designed to assess the immediate effects of ethanol (EtOH) exposure on intracellular signaling activated by BMPs (Bone Morphogenetic Proteins).
Naila Habeeb, Sheyda Najafi, Jeanette C. Perron   +2 more
doaj   +1 more source

Bmp and Shh Signaling Mediate the Expression of satb2 in the Pharyngeal Arches [PDF]

, 2013
Kelly Sheehan-Rooney is with UT Austin, Mary E. Swartz is with UT Austin, C. Ben Lovely is with UT Austin, Michael J. Dixon is with University of Manchester, Johann K. Eberhart is with UT Austin.In human, mutation of the transcription factor SATB2 causes
Sheehan-Rooney, Kelly, Lovely C. Ben, Michael J Dixon, Johann K Eberhart, Lovely, C. Ben, C. Ben Lovely (392946), Swartz Mary E., Dixon, Michael J., Kelly Sheehan-Rooney (392945), Mary E. Swartz (42), Dixon Michael J., Mary E Swartz, Johann K. Eberhart (392947), Eberhart, Johann K., Michael J. Dixon (174991), Eberhart Johann K., Swartz, Mary E., Kelly Sheehan-Rooney, Sheehan-Rooney Kelly, C Ben Lovely   +19 more
core   +2 more sources

BMP signalling: agony and antagony in the family [PDF]

Trends in Cell Biology, 2015
Bone morphogenetic proteins (BMPs) are secreted extracellular matrix (ECM)-associated proteins that regulate a wide range of developmental processes, including limb and kidney formation. A critical element of BMP regulation is the presence of secreted antagonists that bind and inhibit BMP binding to their cognate Ser/Thr kinase receptors at the plasma ...
Brazil, Derek P., Church, Rachel H., Surae, Satnam, Godson, Catherine, Martin, Finian   +4 more
openaire   +3 more sources

Suppression of BMP signaling by PHD2 deficiency in Pulmonary Arterial hypertension

Pulmonary Circulation, 2022
BMP signaling deficiency is evident in the lungs of patients with pulmonary arterial hypertension. We demonstrated that PHD2 deficiency suppresses BMP signaling in the lung endothelial cells, suggesting the novel mechanisms of dysregulated BMP signaling ...
Bin Liu, Dan Yi, Jiakai Pan, Jingbo Dai, Maggie M. Zhu, You‐Yang Zhao, S. Paul Oh, Michael B. Fallon, Zhiyu Dai   +8 more
doaj   +1 more source

BMP signaling in the nephron progenitor niche [PDF]

Pediatric Nephrology, 2011
Bone morphogenic proteins (BMPs) play diverse roles in embryonic kidney development, regulating essential aspects of both ureteric bud and nephron development. In this review, we provide an overview of reported expression patterns and functions of BMP signaling components within the nephrogenic zone or nephron progenitor niche of the developing kidney.
Leif, Oxburgh, Aaron C, Brown, Jennifer, Fetting, Beth, Hill   +3 more
openaire   +2 more sources

BMP signaling and early embryonic patterning [PDF]

Cytokine & Growth Factor Reviews, 2005
Bone morphogenetic proteins (BMPs) play pleiotropic roles during embryonic development as well as throughout life. Recent genetic approaches especially using the mouse gene knockout system revealed that BMP signaling is greatly involved in early embryonic patterning, which is a dynamic event to establish three-dimensional polarities.
Kishigami, Satoshi, Mishina, Yuji
openaire   +3 more sources

Opposing nodal and BMP signals regulate left-right asymmetry in the sea urchin larva.

PLoS Biology, 2012
Nodal and BMP signals are important for establishing left-right (LR) asymmetry in vertebrates. In sea urchins, Nodal signaling prevents the formation of the rudiment on the right side.
Yi-Jyun Luo, Yi-Hsien Su
doaj   +1 more source

Loss of the BMP antagonist, SMOC-1, causes Ophthalmo-Acromelic (Waardenburg Anophthalmia) syndrome in humans and mice [PDF]

, 2011
Ophthalmo-acromelic syndrome (OAS), also known as Waardenburg Anophthalmia syndrome, is defined by the combination of eye malformations, most commonly bilateral anophthalmia, with post-axial oligosyndactyly.
Jackson, Ian J., Peter Branney, Rainger, Joe, Bardakjian, Tanya M, Sokhi, K., Pallotta, Rosanna, Koenig Rainer, Malcolm Fisher, McKie Lisa, Anita Wischmeijer, Fisher, M., Sérgio B. Sousa, Kishan Sokhi, Brunner, Han G, Mégarbané Andre, Fisher, Malcolm, Gillessen-Kaesbach, G., Sousa, Sérgio B., Bokhoven, J.H.L.M. van, Hennekam, Raoul C., Al-Gazali, L., Wischmeijer, Anita, FitzPatrick David R., Semerci, C. Nur, Andrea Superti Furga, Philippe Gautier, Ramos, Lina, Hennekam, Raoul, Bardakjian, T.M., Perry Paul, Semerci, C Nur, Pallotta Rosanna, van Beusekom Ellen, Ramos, L., Khan, Ayesha, Wieczorek, D, Lisa McKie, Ian J Jackson, Gillessen-Kaesbach Gabriele, Bicknell Louise, Saemah Zafar, Raoul Hennekam, Ferda Ozkinay, Elcioglu, Nursel, Fitzpatrick, David R, Adele S Schneider, Gillessen-Kaesbach, Gabriele Gertrud, Ramos Lina, Hennekam Raoul, Rosanna Pallotta, Lihadh Al-Gazali, Dagmar Wieczorek, Megarbane, A., Zafar, Saemah, van Bokhoven, H., Paul Perry, Rainer Koenig, Perry, P., Schneider, Adele S., Ian J. Jackson, Gautier Philippe, Semerci C. Nur, Gautier, P., C. Nur Semerci, Koenig, Rainer, Morrison, Harris, Gautier, Philippe, Bicknell, L., Al-Gazali Lihadh, Elcioglu Nursel, Saponari Anita, Furga, A.S., McKie, L., Han G Brunner, Ellen van Beusekom, Han G. Brunner, Sokhi Kishan, Zafar Saemah, Semerci, C.N., David Sexton, van Bokhoven, Hans, Gabriele Gillessen-Kaesbach, Sousa Sérgio B., Garavelli Livia, Ramsay, Jacqueline K, Lina Ramos, Schneider, Adele S, Ramsay Jacqueline K., Jackson Ian J., Rainger, J., Anita Saponari, FitzPatrick, D.R., Al-Gazali, Lihadh, Bicknell, Louise, Wieczorek, Dagmar, Elcioglu, N., Ayesha Khan, David R Fitzpatrick, Garavelli, Livia, Wieczorek, D., Jackson, Ian J, Sokhi, Kishan, Sexton, D., Jacqueline K Ramsay, Schneider, A.S., Harris Morrison, Adele S. Schneider, Hans van Bokhoven, Sexton David, Rainger Joe, Gillessen-Kaesbach, Gabriele, Beusekom, E. van, Furga, Andrea Superti, Brunner, Han G., Mégarbané, Andre, Wischmeijer, A., Wischmeijer Anita, Brunner, H.G., Tanya M Bardakjian, Pallotta, R., Hennekam, R., Branney Peter, Ozkinay, Ferda, Branney, Peter, Andre Mégarbané, Fisher Malcolm, Brunner Han G., FitzPatrick, David R., Morrison Harris, Bardakjian, Tanya M., Ozkinay, F., Khan, A., Sousa, S.B., Furga Andrea Superti, Jackson, I.J., Bokhoven, Hans van, David R. FitzPatrick, Özkınay, Ferda, Ozkinay Ferda, van Bokhoven Hans, Saponari, Anita, Jacqueline K. Ramsay, Garavelli, L., Tanya M. Bardakjian, Perry, Paul, Sexton, David, Nursel Elcioglu, Zafar, S., Bardakjian Tanya M., Khan Ayesha, Saponari, A., Branney, P., Sousa, Sérgio B, Sérgio B Sousa, van Beusekom, E., Louise Bicknell, Ramsay, Jacqueline K., Schneider Adele S., van Beusekom, Ellen, C Nur Semerci, Ramsay, J.K., Livia Garavelli, Wieczorek Dagmar, Joe Rainger, Beusekom, Ellen van, McKie, Lisa, Koenig, R., Morrison, H.   +167 more
core   +3 more sources

Effect of sonic hedgehog/β-TCP composites on bone healing within the critical-sized rat femoral defect [PDF]

, 2013
The creation of entirely synthetically derived bone substitute materials which are as effective as autologous bone grafts is desirable. Osteogenesis involves the concerted action of several proteins within a signaling cascade.
Henrich, Dirk, Marzi, Ingo, Seebach, Caroline, Flinspach, Armin Niklas, Wenger, Florian, Warzecha, Jörg   +5 more
core   +1 more source

USP15 targets ALK3/BMPR1A for deubiquitylation to enhance bone morphogenetic protein signalling [PDF]

, 2014
Protein kinase ALK3/BMPR1A mediates bone morphogenetic protein (BMP) signalling through phosphorylation and activation of SMADs 1/5/8. SMAD6, a transcriptional target of BMP, negatively regulates the BMP pathway by recruiting E3 ubiquitin ligases and ...
Bruce, David, Smith, James C., Dingwell, Kevin S., Cummins, Timothy D., Ewan, Richard, Macartney, Thomas, Al-Salihi, Mazin A., Weidlich, Simone, Vogt, Janis, Herhaus, Lina, Sapkota, Gopal P., Wasmus, Lise   +11 more
core   +1 more source