Results 141 to 150 of about 38,639 (266)

Specific lipid magnetic sphere sorted CD146-positive bone marrow mesenchymal stem cells can better promote articular cartilage damage repair

BMC Musculoskeletal Disorders
Background The characteristics and therapeutic potential of subtypes of bone marrow mesenchymal stem cells (BMSCs) are largely unknown. Also, the application of subpopulations of BMSCs in cartilage regeneration remains poorly characterized.
Hanru Ren, Lele Zhang, Xu Zhang, Chengqing Yi, Lianghao Wu   +4 more
doaj   +1 more source

EMF treatment delays mesenchymal stem cells senescence during long-term in vitro expansion by modulating autophagy

Frontiers in Cell and Developmental Biology
IntroductionBone marrow mesenchymal stem cells (BMSCs) are widely used in tissue engineering and regenerative medicine as seed cells. Due to low amount in bone marrow, BMSCs must be expanded and cultured in vitro before application.
Wenxiang Cai, Yifan Xiao, Yifan Xiao, Jiyuan Yan, Hao Peng, Chang Tu   +5 more
doaj   +1 more source

Mitochondrial transfer in acute myeloid leukaemia and multiple myeloma: Mechanisms, consequences and potential therapeutic opportunities

The FEBS Journal, EarlyView.
Mitochondria can be transferred from bone marrow cells to cancer cells in acute myeloid leukaemia and multiple myeloma, boosting tumour energy production, growth, and drug resistance. This review highlights key transfer mechanisms and shows how targeting mitochondrial movement and dynamics may offer new therapeutic strategies to limit cancer ...
Ebubechukwu Nwarunma, Mark T. S. Williams   +1 more
wiley   +1 more source

Inflammation‐Regeneration Axis of Dental Pulp Stem Cells: Wnt/NF‐κB Crosstalk

International Endodontic Journal, EarlyView.
ABSTRACT Background Inflammation critically determines dental pulp regenerative outcomes, with dental pulp stem cells (DPSCs) orchestrating tissue homeostasis through differentiation, self‐renewal and immunomodulation processes dynamically regulated by Wnt/β‐catenin and NF‐κB signaling crosstalk.
V. Rajasekar, M. Huang, M. M. Abdalla, P. Neelakantan, C. K. Y. Yiu   +4 more
wiley   +1 more source

Hypoxic Bone Mesenchymal Stem Cell-Derived Exosomes Direct Schwann Cells Proliferation, Migration, and Paracrine to Accelerate Facial Nerve Regeneration via circRNA_Nkd2/miR-214-3p/MED19 Axis

International Journal of Nanomedicine
Haopeng Wang,1,* Hua Zhao,1,* Zheng Chen,1,* Xiaomin Cai,1 Xuhui Wang,1 Ping Zhou,1 Yinda Tang,1 Tingting Ying,1 Xin Zhang,1 Yiman Shen,1 Baimiao Wang,1 Wanchun Zhu,1 Jin Zhu,1 Xinjun Wang,2 Shiting Li1 1Department of Neurosurgery, Xinhua ...
Wang H, Zhao H, Chen Z, Cai X, Wang X, Zhou P, Tang Y, Ying T, Zhang X, Shen Y, Wang B, Zhu W, Zhu J, Wang X, Li S   +14 more
doaj  

Harnessing the Therapeutic Potential of Cell Secretomes and Extracellular Vesicles for Craniofacial Regenerative Applications

Journal of Periodontal Research, EarlyView.
The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag, Magdalena Mayol, Danijel Domic, Madhusudhan Reddy Bobbili, Johannes Grillari, Mariano Sanz, Reinhard Gruber   +6 more
wiley   +1 more source

Notch signaling suppresses glucose metabolism in mesenchymal progenitors to restrict osteoblast differentiation [PDF]

, 2018
Fanxin Long, Hart, Ismaili, Kitagawa, Megason, Seung-Yon Lee   +5 more
core   +2 more sources

Cell Therapy for Periodontal, Soft‐Tissue, and Craniofacial Regeneration

Journal of Periodontal Research, EarlyView.
The clinical translation of mesenchymal stem/stromal cells (MSCs) represents a major advancement in dentistry, especially for periodontal, soft‐tissue, and craniofacial regeneration. However, several challenges remain to be addressed, including the absence of standardised protocols, limited scalability, regulatory hurdles, a lack of well‐controlled ...
Kamal Mustafa, Shuntaro Yamada, Nerea Sanchez, Magdalena Mayol, Cecilie Gjerde, Mariano Sanz   +5 more
wiley   +1 more source

Perils and Promises of Therapeutic Approaches for the Stem Cell Disease Fibrous Dysplasia [PDF]

, 2019
Saggio, Isabella
core   +1 more source

Reconstruction of maxillofacial bone defects: Contemporary methods and future techniques [PDF]

, 2014
Reconstruction of maxillofacial continuity defects has always been a challenging tasks for the scientist and surgeons over the years. The main goal of the reconstruction of the maxillofacial region is to restore facial form, function, full ...
Alfotawi, R., Ayoub, A.
core