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Ferrostatin-1 improves BMSC survival by inhibiting ferroptosis

Archives of Biochemistry and Biophysics, 2023
To investigate the effect of ferroptosis in BMSCs and explore the protective metabolism of ferrostatin-1 under GSDH treatment.BMSCs were treated with GSDH to simulate the damaged microenvironment in vivo to establish a cell injury model. Propidium iodide and CCK8 were utilized to detect the ratio of dead cells and cell viability. DCFH-DA and Amplex Red,
Qiumin, Xie   +10 more
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[Advances of BMSCs in tumor therapy].

Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2009
To review researches of BMSCs in tumor therapy.The recent relevant literature was extensively reviewed. The tropism of BMSCs to cancer, the effect of BMSCs on tumor growth and the application of BMSCs in tumor therapy were summarized.BMSCs has the tropism to tumor and may inhibit or enhance growth of tumor.
Jingcong, Luo, Zhiming, Yang
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Transfection of Noggin in bone marrow stromal cells (BMSCs) enhances BMSC‐induced functional outcome after stroke in rats

Journal of Neuroscience Research, 2011
AbstractEarly intervention with intravenous administration of bone marrow stromal cells (BMSCs) reduces infarction size and ameliorates functional deficits in rat ischemia models. Noggin, an inhibitor of bone morphogenetic protein (BMP), has been demonstrated to provide protection from ischemic disease.
Chen, Chen, Yan, Cheng, Jieli, Chen
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Vaspin deficiency failed to promote the proliferation of BMSCs in osteoarthritis

International Journal of Rheumatic Diseases, 2020
AbstractObjectiveThe aim of this study was to estimate the possible role of vaspin in the proliferation of bone mesenchymal stem cells (BMSCs) and its molecular mechanisms in the bone marrow microenvironment of osteoarthritis (OA).MethodsThis study included 15 non‐obese elderly patients with severe knee OA and 15 non‐obese controls with femoral neck ...
Junfeng Wang   +2 more
openaire   +2 more sources

BMSC Sheets for Ligament Tissue Engineering

2009
The anterior cruciate ligament (ACL) has poor capabilities of healing. Currently, allografts or autografts are used to repair the injury site. But healing of the ACL following autograft or allograft reconstruction has been found slow. Thus, other methods like reconstruction of the ACL are being investigated. Most work in ligament tissue engineering has
E. Y. S. See, S. L. Toh, J. C. H. Goh
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The role of bFGF in down-regulating α-SMA expression of chondrogenically induced BMSCs and preventing the shrinkage of BMSC engineered cartilage

Biomaterials, 2011
Bone marrow stromal cells (BMSCs) have proved to be an ideal cell source for cartilage regeneration. Our previous studies demonstrated that a three-dimensional (3D) cartilage could be constructed successfully in vitro using BMSCs and biodegradable scaffolds.
Qiong, Li   +7 more
openaire   +2 more sources

[Experimental study of the inducing BMSCs into osteogenesis].

Shanghai kou qiang yi xue = Shanghai journal of stomatology, 2004
To study the bone tissue osteogenesis ability of bone marrow stromal cells (BMSCs) in vitro and in vivo.The BMSCs were separated by gradient centrifugation on Percoll, culture-expanded and induced with a conditional medium. The cells were examined by transmission electron microscopy and histochemistry or immunochemistry stains technique including AKP ...
Min, Wang   +6 more
openaire   +1 more source

Comparison of DNA methylation in Tau Promoter region between BMSC and BMSC-derived neurons

Cell Biology International, 2010
Wenhai Yan   +7 more
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Reply to comments on a proposed semantics for BMSCs

The Computer Journal, 1994
Introduction. We thank the editor for giving us the opportunity to reply to the comments of Ladkin and Leue. We will start with a brief explanation of the context and history of our work. (This information was not in our paper, because it is not directly relevant to the subject.)
Mauw, S., Reniers, M.A.
openaire   +1 more source

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