Results 121 to 130 of about 13,811 (214)

BNIP3 expression in endometrial cancer relates to active hypoxia inducible factor 1alpha pathway and prognosis.

, 2008
AIMS: BNIP3 is a pro-apoptotic mitochondrial protein induced under hypoxic stress, with the BNIP3 gene being under direct regulation of the hypoxia-inducible HIF-1alpha transcription factor.
Gatter, Kevin, Harris, AL, Koukourakis, MI, Giatromanolaki, A, Sivridis, E, Gatter, KC   +5 more
core   +1 more source

Purification of BNIP3-GFP v1

This protocol details the purification of BNIP3-GFP.
openaire   +1 more source

BNIP3-mediated mitophagy aggravates placental injury in preeclampsia via NLRP1 inflammasome

Frontiers in Immunology
IntroductionPreeclampsia (PE) is a hypertensive disorder of pregnancy characterized by pronounced placental oxidative stress and inflammatory damage. However, the contribution of mitophagy to inflammation-induced placental injury in PE remains unclear ...
Man Zhao, Zexin Yang, Yan Kang, Zhenya Fang, Changqing Zhang, Chunying Wang, Meijuan Zhou, Junjun Guo, Anna Li, Meihua Zhang   +9 more
doaj   +1 more source

BNIP3 induction in HEK 293 cells reduces cell growth.

, 2018
HEK293 cells were engineered to stably co-express the Tet Repressor protein (TR) and tetracycline-inducible BNIP3 (TO-BNIP3) or beta-galactosidase (TO-β-gal) as described in the Materials & Methods.
Amandeep Singh (3511400), Spencer B. Gibson (416061), Miriam D. Shymko (5848277), Sachin Katyal (218909), Meghan Azad (3747673), David D. Eisenstat (5848280), Elizabeth S. Henson (589791)   +6 more
core   +1 more source

Purification of BNIP3-GST v1

This protocol details the purification of BNIP3-GST.
openaire   +1 more source

VDR restores the expression of PINK1 and BNIP3 in TECs of streptozotocin-induced diabetic mice

Life Science Alliance
VDR protects against fibrosis and defective mitophagy in diabetic mice by regulating mitophagy-related proteins PINK1 and BNIP3. Defective mitophagy in renal tubular epithelial cells is one of the main drivers of renal fibrosis in diabetic kidney disease.
Cheng Yang, Bin Yi, Shikun Yang, Aimei Li, Jishi Liu, Jianwen Wang, Jun Liu, Zhi Li, Qin Liao, Wei Zhang, Hao Zhang   +10 more
doaj   +1 more source

BNIP3 Gene [PDF]

, 2020
openaire   +1 more source

Semaglutide attenuates doxorubicin-induced cardiotoxicity by ameliorating BNIP3-Mediated mitochondrial dysfunction

Redox Biology
Aims: Doxorubicin is a powerful chemotherapeutic agent for cancer, whose use is limited due to its potential cardiotoxicity. Semaglutide (SEMA), a novel analog of glucagon-like peptide-1 (GLP-1), has received widespread attention for the treatment of ...
Xiaoping Li, Wenbin Luo, Yang Tang, Jiangjiao Wu, Junkai Zhang, Shengnan Chen, Lu Zhou, Yu Tao, Yuanjuan Tang, Fengxian Wang, Yu Huang, Pedro A. Jose, Li Guo, Chunyu Zeng   +13 more
doaj   +1 more source

The involvement of BNIP3 in cyanide-induced neurotoxicity

, 2008
In this study, an immortalized dopaminergic cell line was used to characterize the cell death signaling cascade activated by cyanide. Cyanide-treated cells exhibited a time- and concentration-dependent apoptosis that was caspase-independent.
Zhang, Lu
core  

Lipid droplet turnover at the lysosome inhibits growth of hepatocellular carcinoma in a BNIP3-dependent manner [PDF]

Hepatic steatosis is a major etiological factor in hepatocellular carcinoma (HCC), but factors causing lipid accumulation leading to HCC are not understood.
Bock-Hughes, Althea, Terry, Alexander R., Drake, Lauren E., Berardi, Damian E., Bozek, Grazyna, Macleod, Kay F.   +5 more
core   +1 more source