BNIP3 Plays Crucial Roles in the Differentiation and Maintenance of Epidermal Keratinocytes
Transcriptome analysis of the epidermis of Hes1−/− mouse revealed the direct relationship between Hes1 (hairy and enhancer of split-1) and BNIP3 (BCL2 and adenovirus E1B 19-kDa-interacting protein 3), a potent inducer of autophagy.
Osawa, Masatake +5 more
core +1 more source
Protect neurons from ischemia-induced death by targeting BNIP3 gene family
The BNIP3 family, a group of death-inducing mitochondrial proteins, includes BNIP3, NIX and BNIP3h. These proteins share structural and functional similarities.
Weng, Jiequn
core
Reverse engineering of BNIP3 identifies a mitochondrial protective peptide. [PDF]
Hendgen-Cotta UB +29 more
europepmc +1 more source
The mechanism and therapeutic prospect of HIF-1 α/BNIP3 pathway in regulating mitophagy in tubulointerstitial fibrosis. [PDF]
Wang X, Guo Z.
europepmc +1 more source
Backbone Nitrogen Substitution Probes the Role of Glycine Residues at GxxxG Interfaces in Transmembrane Helices. [PDF]
Thomas D, Gu F, Newberry RW.
europepmc +1 more source
Hydroxysafflor Yellow A Regulates SIRT1-FOXO3-BNIP3 Signaling Pathway to Promote Mitophagy: A Novel Therapeutic Strategy for Myocardial Ischemia-Reperfusion Injury. [PDF]
Meng D +5 more
europepmc +1 more source
BNIP3-Dependent Mitophagy Non-Autonomously Regulates Systemic Aging via NF-κB Suppression in Drosophila. [PDF]
Deng Z +11 more
europepmc +1 more source
Investigating the role of nuclear BNIP3 in regulation of cellular proliferation
BNIP3 is a member of BCL-2 family of cell death regulating proteins. When overexpressed in the cytoplasm under stress conditions such as hypoxia, BNIP3 localizes to the mitochondria and promotes cell death through mitochondrial dysfunction.
Singh, Amandeep
core
Nanoparticle-based serine replenishment rescues SP1-BNIP3 mitophagy and ameliorates preeclampsia in preclinical models. [PDF]
Wang Y +16 more
europepmc +1 more source

