Results 131 to 140 of about 19,187 (211)

EndoG links Bnip3-induced mitochondrial damage and caspase-independent DNA fragmentation in ischemic cardiomyocytes.

PLoS ONE, 2011
Mitochondrial dysfunction, caspase activation and caspase-dependent DNA fragmentation are involved in cell damage in many tissues. However, differentiated cardiomyocytes repress the expression of the canonical apoptotic pathway and their death during ...
Jisheng Zhang, Junmei Ye, Albert Altafaj, Maria Cardona, Núria Bahi, Marta Llovera, Xavier Cañas, Stuart A Cook, Joan X Comella, Daniel Sanchis   +9 more
doaj   +1 more source

Purification of BNIP3-GFP v1

This protocol details the purification of BNIP3-GFP.
openaire   +1 more source

Hypermethylated gene ANKDD1A is a candidate tumor suppressor that interacts with FIH1 and decreases HIF1α stability to inhibit cell autophagy in the glioblastoma multiforme hypoxia microenvironment. [PDF]

, 2019
Ectopic epigenetic mechanisms play important roles in facilitating tumorigenesis. Here, we first demonstrated that ANKDD1A is a functional tumor suppressor gene, especially in the hypoxia microenvironment.
Fan, Li, Feng, Jianbo, Fu, Haijuan, Li, Guiyuan, Li, Peiyao, Liu, Changhong, Liu, Qiang, Liu, Qing, Ren, Xing, She, Xiaoling, Sun, Yingnan, Wu, Minghua, Zhang, Yan, Zhao, Chunhua   +13 more
core   +1 more source

Transcriptional Response to Acute Thermal Exposure in Juvenile Chinook Salmon Determined by RNAseq. [PDF]

, 2015
Thermal exposure is a serious and growing challenge facing fish species worldwide. Chinook salmon (Oncorhynchus tshawytscha) living in the southern portion of their native range are particularly likely to encounter warmer water due to a confluence of ...
Baerwald, Melinda R, Fangue, Nann A, May, Bernie P, Meek, Mariah H, Rincón, Gonzalo, Stephens, Molly R, Tomalty, Katharine MH   +6 more
core  

Purification of BNIP3-GST v1

This protocol details the purification of BNIP3-GST.
openaire   +1 more source

KPNB1-ATF4 induces BNIP3-dependent mitophagy to drive odontoblastic differentiation in dental pulp stem cells

Cellular & Molecular Biology Letters
Background Differentiating dental pulp stem cells (DPSCs) into odontoblasts is a critical process for tooth self-repair and dentine‒pulp engineering strategies in the clinic.
Zeying Zhang, Di Yang, Xiaoyuan Yan, Qiujing Qiu, Jiajie Guo, Lihong Qiu   +5 more
doaj   +1 more source

BNIP3-mediated mitophagy aggravates placental injury in preeclampsia via NLRP1 inflammasome

Frontiers in Immunology
IntroductionPreeclampsia (PE) is a hypertensive disorder of pregnancy characterized by pronounced placental oxidative stress and inflammatory damage. However, the contribution of mitophagy to inflammation-induced placental injury in PE remains unclear ...
Man Zhao, Zexin Yang, Yan Kang, Zhenya Fang, Changqing Zhang, Chunying Wang, Meijuan Zhou, Junjun Guo, Anna Li, Meihua Zhang   +9 more
doaj   +1 more source

Membrane translocation and oligomerization of hBok are triggered in response to apoptotic stimuli and Bnip3 [PDF]

, 2018
.: hBok is a human pro-apoptotic member of the Bcl-2 family. By fluorescence in situ hybridization and in silico analysis, hBok was found to be located on chromosome 2q37.3.
Dürrenberger, M., Fu, W., Gao, S., Geyter, C., Zhang, H.   +4 more
core  

Semaglutide attenuates doxorubicin-induced cardiotoxicity by ameliorating BNIP3-Mediated mitochondrial dysfunction

Redox Biology
Aims: Doxorubicin is a powerful chemotherapeutic agent for cancer, whose use is limited due to its potential cardiotoxicity. Semaglutide (SEMA), a novel analog of glucagon-like peptide-1 (GLP-1), has received widespread attention for the treatment of ...
Xiaoping Li, Wenbin Luo, Yang Tang, Jiangjiao Wu, Junkai Zhang, Shengnan Chen, Lu Zhou, Yu Tao, Yuanjuan Tang, Fengxian Wang, Yu Huang, Pedro A. Jose, Li Guo, Chunyu Zeng   +13 more
doaj   +1 more source

BNIP3 Gene [PDF]

, 2020
openaire   +1 more source