Results 151 to 160 of about 21,955 (252)

KPNB1-ATF4 induces BNIP3-dependent mitophagy to drive odontoblastic differentiation in dental pulp stem cells

Cellular & Molecular Biology Letters
Background Differentiating dental pulp stem cells (DPSCs) into odontoblasts is a critical process for tooth self-repair and dentine‒pulp engineering strategies in the clinic.
Zeying Zhang, Di Yang, Xiaoyuan Yan, Qiujing Qiu, Jiajie Guo, Lihong Qiu   +5 more
doaj   +1 more source

BNIP3-mediated mitophagy aggravates placental injury in preeclampsia via NLRP1 inflammasome

Frontiers in Immunology
IntroductionPreeclampsia (PE) is a hypertensive disorder of pregnancy characterized by pronounced placental oxidative stress and inflammatory damage. However, the contribution of mitophagy to inflammation-induced placental injury in PE remains unclear ...
Man Zhao, Zexin Yang, Yan Kang, Zhenya Fang, Changqing Zhang, Chunying Wang, Meijuan Zhou, Junjun Guo, Anna Li, Meihua Zhang   +9 more
doaj   +1 more source

Purification of BNIP3-GST v1

This protocol details the purification of BNIP3-GST.
openaire   +1 more source

Hypoxia‐inducible factor prolyl hydroxylase inhibitor alleviates heatstroke‐induced acute kidney injury by activating BNIP3‐mediated mitophagy

The FASEB Journal
Hypoxia‐induced inflammation and apoptosis are important pathophysiological features of heat stroke‐induced acute kidney injury (HS‐AKI). Hypoxia‐inducible factor (HIF) is a key protein that regulates cell adaptation to hypoxia.
Ling Wang, Yongwei Song, Pan Zhang, Wen-Ting Chen, Fei Xiao, Ping Zhou, Xuesen Yang, Huanzi Dai   +7 more
semanticscholar   +1 more source

BNIP3 Gene [PDF]

, 2020
openaire   +1 more source

Transcriptional Response to Acute Thermal Exposure in Juvenile Chinook Salmon Determined by RNAseq. [PDF]

, 2015
Thermal exposure is a serious and growing challenge facing fish species worldwide. Chinook salmon (Oncorhynchus tshawytscha) living in the southern portion of their native range are particularly likely to encounter warmer water due to a confluence of ...
Baerwald, Melinda R, Fangue, Nann A, May, Bernie P, Meek, Mariah H, Rincón, Gonzalo, Stephens, Molly R, Tomalty, Katharine MH   +6 more
core  

Impaired DNA double-strand break repair contributes to chemoresistance in HIF-1α-deficient mouse embryonic fibroblasts [PDF]

, 2017
A mismatch between metabolic demand and oxygen delivery leads to microenvironmental changes in solid tumors. The resulting tumor hypoxia is associated with malignant progression, therapy resistance and poor prognosis.
Balamurugan, Kuppusamy, Stiehl, Daniel P., Wenger, Roland H., Wirthner, Renato, Wrann, Simon   +4 more
core  

AAA237, an SKP2 inhibitor, suppresses glioblastoma by inducing BNIP3-dependent autophagy through the mTOR pathway

Cancer Cell International
Glioblastoma (GBM) is the most common brain tumor with the worst prognosis. Temozolomide is the only first-line drug for GBM. Unfortunately, the resistance issue is a classic problem. Therefore, it is essential to develop new drugs to treat GBM.
Yizhi Zhang, Wan Li, Yihui Yang, Sen Zhang, Hong Yang, Yue Hao, Xu Fang, Guanhua Du, Jianyou Shi, Lianqiu Wu, Jinhua Wang   +10 more
semanticscholar   +1 more source

BNIP3 wt Allele [PDF]

, 2020
openaire   +1 more source

Pajanan Hipoksia Hipobarik Intermiten Menurunkan Metabolisme Anaerobik Pada Tikus Jantan Spraque Dawley [PDF]

, 2010
Hipoksia hipobarik intermiten (HHI) sering dialami oleh para penerbang maupun awak pesawat. Jika hipoksia berlanjut, maka terjadi metabolisme anaerobik yang berlebihan dan gangguan pada mitokondria yang menyebabkan apoptosis.
Achmad, T. H. (Tri), Hernowo, B. S. (Bethy), Hidayat, A. (Achmad), Wiradisastra, K. (Kahdar)   +3 more
core