Results 151 to 160 of about 19,187 (211)

BNIP3 IN MELANOMA: SITTING ON THE IRON THRONE Unraveling the role of BNIP3 in mitochondrial homeostasis, metabolism and melanoma growth

, 2021
Melanoma is the deadliest form of skin cancer due to its ability to metastasize rapidly and to become resistant to various forms of therapies. To support their aggressive phenotype, melanoma cells require metabolic plasticity, which they acquire by hijacking key adaptive responses like the hypoxia-inducible response and autophagy.
openaire   +1 more source

The Role of HIF-1α/BNIP3 Pathway in Hippocampal Neuronal Autophagy in Epilepsy. [PDF]

Mol Neurobiol
Kuang H, Meng Y, Qin X, Qian K, Gong C, Li S, Zhang L, Gan X, Lu Y, Wu Y.   +9 more
europepmc   +1 more source

Cathepsin L as a dual-target to mitigate muscle wasting while enhancing anti-tumor efficacy of anti-PD-L1. [PDF]

Nat Commun
Park SY, Son K, Kim J, Kim K, Joo S, Kim B, Lee M, Kim W, Jung WJ, Choi BK, Jeon N, Chung WY, Hu Y, Lee H, Song NY.   +14 more
europepmc   +1 more source

Hypoxic BMSC-derived exosomes-induced mitophagy quenches intestinal inflammation via HIF-1α/BNIP3 pathway. [PDF]

Sci Rep
Zhu F, Wang J, Yuan Y, Wei C, Gao F, Liu X, Li J, Yi Z, Zhang L, Fan H.   +9 more
europepmc   +1 more source

HMOX1 interacts with BNIP3 to modulate neuronal ferroptosis after spinal cord ischemia-reperfusion injury via a mitophagy-dependent mechanism. [PDF]

Cell Death Discov
Duan Y, Zhang Y, Yang F, Zhang M, Shi Y, Ma Z, Huang X, Li W, Lang Y, Hu X, Kang X.   +10 more
europepmc   +1 more source

Receptor-mediated mitophagy: a new target of neurodegenerative diseases. [PDF]

Front Neurol
Yang J, Yang F, Chen G, Liu M, Yuan S, Zhang TE.   +5 more
europepmc   +1 more source

Functional Dissection of BH3 Only Protein BNIP3

Functional Dissection of BH3 Only Protein BNIP3
BNIP3 is a pro-apoptotic protein, which contains BH3 and trans-membrane domains. Previous studies demonstrated an association between ceBNIP3, C. elegans homologue of BNIP3, and ced-3. It seemed likely that the interaction between ceBNIP3 and ced-3 was an alternative cascade of caspase activation in C.
openaire  

Mechanism of autophagy initiation by transmembrane selective autophagy receptors. [PDF]

EMBO J
Adriaenssens E, Martens S.
europepmc   +1 more source

Proteomics analysis reveals progesterone receptor induced mitochondria-mediated apoptosis in breast cancer cells. [PDF]

Sci Rep
Woo QY, Lau PK, Lee BTK, Bajalovic N, Lee SH, Leong KS, Pow KY, Hanan S, Meng W, Lai SK, Lin VC.   +10 more
europepmc   +1 more source

Novel anticancer combination therapies using replication-selective oncolytic adenoviruses and chemotherapeutics [PDF]

, 2011
Hammarén Busch, Kristina
core   +1 more source