Alternative BNIP3 splicing in alveolar rhabdomyosarcomal cells
Several cellular phenotypes drive tumorigenesis in alveolar rhabdomyosarcoma. These phenotypes may be attenuated via treatment with non-steroidal antiinflammatory drugs, like aspirin, tolfenamic acid, and indomethacin, which interfere with intracellular prostaglandin synthesis and induce cell death.
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Prognostic and Immunomodulatory Roles of BNIP3 in Osteosarcoma Revealed by Integrated Single-Cell and Bulk Transcriptomic Profiling. [PDF]
Li J, Wang W, Li L, Yu K.
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SARM1 Regulates BNIP3-Mediated Mitochondrial Quality Control in Diabetic Hearts. [PDF]
Nizami HL +9 more
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HIF-1α/BNIP3-mediated mitophagy mitigates cerebral ischemia/reperfusion injury in rats by suppressing NLRP3 inflammasome activation. [PDF]
Huo Q, Zhang Y, Zhao J, Bai N, Wang J.
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Mitophagy in pancreatic cancer: mechanistic insights and implications for novel therapeutic strategies. [PDF]
Wang Z +7 more
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Association of HIF1α, BNIP3, and BNIP3L with Hypoxia-Related Metabolic Stress in Metabolic Syndrome. [PDF]
Kıran TR +4 more
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Effect of Mitophagy on the Tension-Driven Osteogenic Differentiation of Periodontal Ligament Stem Cells During Ageing. [PDF]
Peng C +5 more
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Melanoma is the deadliest form of skin cancer due to its ability to metastasize rapidly and to become resistant to various forms of therapies. To support their aggressive phenotype, melanoma cells require metabolic plasticity, which they acquire by hijacking key adaptive responses like the hypoxia-inducible response and autophagy.
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Trajectories of serum HIF-1α and BNIP3 are associated with injury severity and outcomes in pediatric traumatic brain injury: a prospective cohort study. [PDF]
Yin H +5 more
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The multifaceted functions of selective autophagy in cancer: molecular basis, consequences, and clinical prospects. [PDF]
Jiang M +19 more
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