Results 21 to 30 of about 3,162 (145)

Lethal Borna disease virus 1 (BoDV-1) infections of humans and animals – in-depth molecular epidemiology and phylogeography: [Preprint] [PDF]

, 2023
Borna disease virus 1 (BoDV-1) is the causative agent of Borna disease, a progressive and mostly fatal neurologic disorder of domestic mammals and humans, resulting from spill-over infection from its natural reservoir host, the bicolored white-toothed ...
Baumgärtner, Wolfgang, Bauswein, Markus, Beer, Martin, Cadar, Daniel, Dürrwald, Ralf, Ebinger, Arnt, Ensser, Armin, Frank, Christina, Fürstenau, Jenny, Hansmann, Florian, Haring, Viola, Herms, Jochen, Hoffmann, Bernd, Homeier-Bachmann, Timo, Kolodziejek, Jolanta, Korn, Klaus, Liesche-Starnecker, Friederike, Matiasek, Kaspar, Mundhenk, Lars, Müller, Matthias, Neubauer-Juric, Antonie, Niller, Hans-Helmut, Nobach, Daniel, Nowotny, Norbert, Pfaff, Florian, Pörtner, Kirsten, Rubbenstroth, Dennis, Ruf, Viktoria, Santos, Pauline, Schlegel, Jürgen, Schlottau, Kore, Schmidt, Barbara, Seuberlich, Torsten, Suchowski, Marcel, Tappe, Dennis, Ulrich, Rainer G., Ulrich, Reiner   +36 more
core   +2 more sources

Evidence of rustrela virus-associated feline staggering disease in Sweden since the 1970s [PDF]

Acta Veterinaria Scandinavica
Background Staggering disease (SD) is a severe neurological disease that has been regularly reported in Swedish cats since the beginning of the 1970s.
Emma Thilén, Dennis Rubbenstroth, Sofia Tengstrand, Florian Pfaff, Jonas Johansson Wensman, Cecilia Ley   +5 more
doaj   +4 more sources

Bornavirus encephalitis shows a characteristic MR phenotype in humans [PDF]

Annals of Neurology, Volume 88, Issue 4, Page 723-735, October 2020., 2020
Objective The number of diagnosed fatal encephalitis in humans caused by the classical Borna disease virus (BoDV‐1) is increasingly recognized, ever since it was proven that BoDV‐1 can cause human infections.
Angstwurm, Klemens, Berlis, Ansgar, Bette, Stefanie, Bornavirus‐Encephalitis Study Group:, Dorn, Franziska, Finck, Tom, Holtmannspötter, Markus, Liesche‐Starnecker, Friederike, Maurer, Christoph, Probst, Monika, Rosati, Marco, Rubbenstroth, Dennis, Ruf, Viktoria, Schlegel, Jürgen, Wendl, Christina, Wiesinger, Isabel, Wiestler, Benedikt, Wunderlich, Silke, Zimmer, Claus   +18 more
core   +2 more sources

Vaccination against Borna Disease: Overview, Vaccine Virus Characterization and Investigation of Live and Inactivated Vaccines [PDF]

Viruses, 2022
(1) Background: Vaccination of horses and sheep against Borna disease (BD) was common in endemic areas of Germany in the 20th century but was abandoned in the early 1990s.
Ralf Dürrwald, Jolanta Kolodziejek, Djin-Ye Oh, Sibylle Herzog, Heinrich Liebermann, Nikolaus Osterrieder, Norbert Nowotny   +6 more
doaj   +3 more sources

Mapping Bornavirus encephalitis-A comparative study of viral spread and immune response in human and animal dead-end hosts. [PDF]

PLoS Pathogens
Borna disease virus 1 (BoDV-1) has long been recognized as a cause of fatal encephalitis in animals and was only recently identified as a zoonotic pathogen causing a similar disease in humans.
Yannik Vollmuth, Nicola Jungbäck, Przemyslaw Grochowski, Tatiana Mögele, Leonhard Stark, Niku S Zarrabi, Jürgen Schlegel, Tina Schaller, Bruno Märkl, Kaspar Matiasek, Friederike Liesche-Starnecker   +10 more
doaj   +2 more sources

Antagonistic activity against innate immunity determines virulence in mammalian bornaviruses [PDF]

npj Viruses
Variegated squirrel bornavirus 1 (VSBV-1) is a lethal emerging disease that has been discovered in privately owned and zoo squirrels, but its pathogenicity as a zoonotic pathogen remains uncertain.
Akiko Makino, Chiaki Tanaka, Kan Fujino, Keizo Tomonaga   +3 more
doaj   +2 more sources

Suppression of Borna Disease Virus Replication during Its Persistent Infection Using the CRISPR/Cas13b System. [PDF]

Int J Mol Sci
Borna disease virus (BoDV-1) is a bornavirus that infects the central nervous systems of various animal species, including humans, and causes fatal encephalitis.
Sasaki S, Ogawa H, Katoh H, Honda T.
europepmc   +3 more sources

Spillover infections by rustrela virus, borna disease virus 1 and tick-borne encephalitis virus revealed by retrospective screening of mammalian encephalitis of unknown origin [PDF]

BMC Veterinary Research
Background Cross-species transmission of several viral neuropathogens may lead to fatal disease in incidental hosts. The newly discovered rustrela virus (RusV) as well as Borna disease virus 1 (BoDV-1), tick-borne encephalitis virus (TBEV), and highly ...
Anne Voss, Anne Günther, Olga Geit, Chloé Puget, Andreas Pauly, Karin Stiasny, Kore Schlottau, Martin Beer, Achim D. Gruber, Angele Breithaupt, Dennis Rubbenstroth, Lars Mundhenk   +11 more
doaj   +2 more sources

First isolation, in-vivo and genomic characterization of zoonotic variegated squirrel Bornavirus 1 (VSBV-1) isolates [PDF]

Emerging Microbes and Infections, 2020
The variegated squirrel bornavirus 1 (VSBV-1), a member of the family Bornaviridae, was discovered in 2015 in a series of lethal human infections. Screening approaches revealed kept exotic squirrels as the putative source of infection.Infectious virus ...
Kore Schlottau, Daniel Nobach, Christiane Herden, Stefan Finke, Martin Beer, Donata Hoffmann   +5 more
doaj   +3 more sources

Developing a universal multi-epitope protein vaccine candidate for enhanced borna virus pandemic preparedness [PDF]

Frontiers in Immunology
IntroductionBorna disease virus 1 (BoDV-1) is an emerging zoonotic RNA virus that can cause severe acute encephalitis with high mortality. Currently, there are no effective countermeasures, and the potential risk of a future outbreak requires urgent ...
Jingjing Zhang, Jingjing Zhang, Jingjing Zhang, Jingjing Zhang, Youfang Yang, Binyu Wang, Wanting Qiu, Helin Zhang, Yuyang Qiu, Jing Yuan, Jing Yuan, Rong Dong, Rong Dong, Rong Dong, Yan Zha, Yan Zha, Yan Zha   +16 more
doaj   +2 more sources