Results 31 to 40 of about 76,436 (252)

Dipyridamole-Coated 3D-Printed β-Tricalcium Phosphate Scaffolds: Spectrophotometric Characterization, Drug Release Kinetics, and In Vitro Evaluation to Guide Critical-Sized Bone Defect Repair Studies. [PDF]

J Funct Biomater
Rasane P, Nayak VV, Weerasinghe Arachchige LC, Rice E, Ashin ZF, Venkatesan B, Varanasi V, Ono N, Young S, Witek L.   +9 more
europepmc   +2 more sources

Strontium Modified Calcium Sulfate Hemihydrate Scaffold Incorporating Ginsenoside Rg1/Gelatin Microspheres for Bone Regeneration

Frontiers in Bioengineering and Biotechnology, 2020
The aim of this study was to prepare a promising biomaterial for bone tissue repair and regeneration. The Strontium – calcium sulfate hemihydrate (Sr-α-CaS) scaffold incorporating gelatin microspheres (GMs) encapsulated with Ginsenoside Rg1 (Rg1) was ...
Peng Luo, Peng Luo, Lan Yu, Qiang Lin, Changde Wang, Dazhi Yang, Dazhi Yang, Shuo Tang   +7 more
doaj   +1 more source

Poster 167: Biomechanics of a Novel Dermal Augmentation Procedure for Subcritical Bone Loss

Orthopaedic Journal of Sports Medicine, 2022
Objectives: Subcritical glenoid bone loss has been associated with high failure rates when treated with standard labral repair. While a Latarjet can provide stability, high complication rates and the risk of long term arthritis makes this procedure less ...
Aaron Wynkoop, Patrick Wang, John Konicek, Sam Akhavan MD   +3 more
doaj   +1 more source

New use for old drug: Local delivery of puerarin facilitates critical-size defect repair in rats by promoting angiogenesis and osteogenesis

Journal of Orthopaedic Translation, 2022
Objectives: Large bone defect repair is a challenging clinical problem due to limited self-repair ability. A well-designed bone filling product should possess the ability to induce tissue in-growth and facilitate neovascularization and new bone formation.
Huijuan Cao, Lingli Li, Ling Li, Xiangbo Meng, Yanzhi Liu, Wenxiang Cheng, Peng Zhang, Yongbo Gao, Ling Qin, Xinluan Wang   +9 more
doaj   +1 more source

Adobe-inspired hydrogel with antibacterial and angiogenic functions for osteoporotic bone defect repair

Materials & Design
Nowadays, the rapid development of tissue engineering technology has provided more treatment options for bone defect repair, but the osteoporotic bone defect repair remains a major challenge.
Qi Guo, Zouwei Li, Renxin Chen, Yezheng Wang, Guang Shi, Mengyue Zhu, Wenping He, Hong Liu, Chao Jian, Shaobo Zhu   +9 more
doaj   +1 more source

Transient activation of notch signaling enhances endogenous stromal cell expansion and subsequent bone defect repair

Journal of Orthopaedic Translation, 2021
Background: Following traumatic bone loss or removal of bone tumors, the failure of bone allograft transplantation for large bone defect repair remains a significant problem in orthopedics. Therefore, new strategies that can efficiently enhance allograft
Guangxi Wang, Jinglong Yan, Hao Zhang, Patrick Massey, J. Steven Alexander, Christopher G. Kevil, Shane Barton, Yufeng Dong   +7 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Research progress on the effect and mechanism of immune cells on osteogenic differentiation of bone marrow mesenchymal stem cells

Kouqiang hemian waike zazhi
The role of bone marrow mesenchymal stem cells (BMSCs) in bone defect repair and bone regeneration has been extensively studied. Much evidence suggests that effective endogenous bone regeneration requires coordination of the immune system.
SHI Yan, GUO Hao, ZHENG Kaijuan, YANG Zhenming, QIANG Jinbiao, SHI Ce   +5 more
doaj   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

FEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez   +3 more
wiley   +1 more source

Oral cavity-derived stem cells and preclinical models of jaw-bone defects for bone tissue engineering

Stem Cell Research & Therapy, 2023
Background Jaw-bone defects caused by various diseases lead to aesthetic and functional complications, which can seriously affect the life quality of patients. Current treatments cannot fully meet the needs of reconstruction of jaw-bone defects.
Jie Zhao, Ying-Hui Zhou, Ya-Qing Zhao, Zheng-Rong Gao, Ze-Yue Ouyang, Qin Ye, Qiong Liu, Yun Chen, Li Tan, Shao-Hui Zhang, Yao Feng, Jing Hu, Marie Aimee Dusenge, Yun-Zhi Feng, Yue Guo   +14 more
doaj   +1 more source