Results 21 to 30 of about 76,436 (252)

Dendritic Mesoporous Silica-Modified Decellularized Bone Matrix Scaffold for Sustained Teriparatide Delivery in Bone Defect Repair: Characterization, Drug Release, and In Vitro Biological Performance. [PDF]

Pharmaceutics
Zhang L, Yang W, Jia S, Shang J, Wang J, Zhao X, Bai H, Wang C.   +7 more
europepmc   +2 more sources

Bone induction and defect repair by true bone ceramics incorporated with rhBMP-2 and Sr

Journal of Materials Science: Materials in Medicine, 2021
Objective: To study the bone induction and defect repair of true bone ceramics (TBC) combined with rhBMP-2 and Sr. Methods: MC3T3-E1 cells were used to evaluate the bioactivity of the composite.
Chunli Zhang, Gang Xu, Liwei Han, Xiantong Hu, Yantao Zhao, Zhonghai Li   +5 more
doaj   +1 more source

Evaluation of safety and efficacy of the bone marrow mesenchymal stem cell and gelatin-nano-hydroxyapatite combination in canine femoral defect repair

Frontiers in Veterinary Science, 2023
Femoral shaft fracture is a common bone trauma in dogs. The limitation of mesenchymal stem cells in bone defect applications is that the cell suspension cannot be fixed to the bone defect site. In the study, our objective was to substantiate the combined
Zihang Ma, Zihang Ma, Xiaoying Guo, Xiaoying Guo, Jun Zhang, Jun Zhang, Jun Zhang, Qifeng Jiang, Qifeng Jiang, Wuying Liang, Wuying Liang, Wenxin Meng, Wenxin Meng, Shuaijiang Chen, Shuaijiang Chen, Yufan Zhu, Yufan Zhu, Cundong Ye, Cundong Ye, Cundong Ye, Kun Jia, Kun Jia   +21 more
doaj   +1 more source

Retrograde island peroneal artery perforator flap combined with Masquelete technique in treatment of postoperative bone infection with tissue defect

Di-san junyi daxue xuebao, 2021
Objective To investigate the clinical effectiveness of retrograde island peroneal artery perforator flap combined with Masquelete technique in the treatment of bone infection with tissue defect after calcaneal fracture.
LIU Yansong, ZHANG Yunhui, YILIZATI Yilihamu, LIU Aipeng, CAO Tianyong, ZHANG Wenhan, FENG Guang   +6 more
doaj   +1 more source

Single-cell RNA sequencing unravels heterogeneity of skeletal progenitors and cell–cell interactions underlying the bone repair process

Regenerative Therapy, 2022
Introduction: Activation of skeletal progenitors upon tissue injury and the subsequent cell fate specification are tightly coordinated in the bone repair process.
Mika Nakayama, Hiroyuki Okada, Masahide Seki, Yutaka Suzuki, Ung-il Chung, Shinsuke Ohba, Hironori Hojo   +6 more
doaj   +1 more source

Development and evaluation of a modified injectable calcium phosphate cement with enhanced injectability and mechanical stability for bone defect repair. [PDF]

BMC Musculoskelet Disord
Zhou X, Wei D, Zhang Z, Liu Y, Miao J, Qian Z.   +5 more
europepmc   +2 more sources

Removal of aging microenvironment of bone defects can effectively promote bone defect repair. [PDF]

J Transl Med
Huang J, Long H, Malik MA, Wu S, Cao X.
europepmc   +2 more sources

The co-culture of ASCs and EPCs promotes vascularized bone regeneration in critical-sized bone defects of cranial bone in rats

Stem Cell Research & Therapy, 2020
Background The repair of critical-sized bone defect represents a challenging problem in bone tissue engineering. To address the most important problem in bone defect repair, namely insufficient blood supply, this study aimed to find a method that can ...
Yuanjia He, Shuang Lin, Qiang Ao, Xiaoning He   +3 more
doaj   +1 more source

Hippo-YAP/TAZ signaling in osteogenesis and macrophage polarization: Therapeutic implications in bone defect repair

Genes and Diseases, 2023
Bone defects caused by diseases or surgery are a common clinical problem. Researchers are devoted to finding biological mechanisms that accelerate bone defect repair, which is a complex and continuous process controlled by many factors.
Haochen Wang, Hui Yu, Tianyu Huang, Bin Wang, Lin Xiang   +4 more
doaj   +1 more source

Histological and Immunohistochemical Analysis of the Effects of Topical Melatonin Treatment Associated with Collagen Sponge and rhBMP-2 Protein on Bone Remodeling

Biomolecules, 2022
Extensive bone defect healing is an important health issue not yet completely resolved. Different alternative treatments have been proposed but, in face of a critical bone defect, it is still very difficult to reach a complete regeneration, with the new ...
Leticia Ferreira Montarele, Dimitrius Leonardo Pitol, Bruno Fiorelini Pereira, Sara Feldman, Valéria Paula Sassoli Fazan, João Paulo Mardegan Issa   +5 more
doaj   +1 more source