Results 1 to 10 of about 72,869 (116)

Biodegradable metals for bone defect repair: A systematic review and meta-analysis based on animal studies

Bioactive Materials, 2021
Biodegradable metals are promising candidates for bone defect repair. With an evidence-based approach, this study investigated and analyzed the performance and degradation properties of biodegradable metals in animal models for bone defect repair to ...
Jiazhen Zhang, Yanbiao Jiang, Zhizhong Shang, Bing Zhao, Mingyue Jiao, Wenbo Liu, Maobo Cheng, Bao Zhai, Yajuan Guo, Bin Liu, Xinli Shi, Bin Ma   +11 more
doaj   +3 more sources

Adelmidrol: A novel osteogenic mineralization regulator for bone defect repair via activating the Notch pathway with drug-loaded hydrogel [PDF]

iScience
Summary: Bone defect, irreversible bone loss impairing physiological functions, raises complication risks, lowers life quality and burdens healthcare, demanding effective novel repair strategies.
Fei Zhang, Fanchao Li, Chao Ren, ke Zhang, Hao Li, Hong Luo, Zhihong Xie, Kun Wei, Yang Liu, Yijie Zhang, Tao Wang, Wuxun Peng   +11 more
doaj   +2 more sources

Research progress on mitochondria in bone defect repair: mechanisms and therapeutic implications [PDF]

Frontiers in Bioengineering and Biotechnology
Bone defect repair faces clinical challenges due to complex conditions caused by various factors such as trauma and aging. Traditional treatments have certain limitations, which seriously affect patients’ prognosis.
Zhicheng Hu, Zhicheng Hu, Gang Chen, Zhisheng Long   +3 more
doaj   +2 more sources

Multimodal mechanisms of platelet-rich plasma in bone defect repair: Angiogenesis, inflammation modulation, and metabolic regulation [PDF]

Regenerative Therapy
Bone defect is the loss of bone tissue due to trauma, fracture, infection, etc. This loss may lead to non-union of fracture, bone defect or bone deficiency, which seriously affects the patient's quality of life and even leads to dysfunction and ...
Junjie Chen, Bo Liu, Jiayang He, Yuhao Wei, Yuhan He, Hang Zhou, Zhiqiang Zhang, Yiwen Weng, Ming Cheng   +8 more
doaj   +2 more sources

In situ magnesium phosphate/polycaprolactone 3D-printed scaffold induce bone regeneration in rabbit maxillofacial bone defect model

Materials & Design, 2022
The development of a scaffold that can be quickly prepared and used to repair maxillofacial bone defects is an urgent clinical need. 3D printing technology can prepare personalized bone defect substitutes according to the computed tomography (CT) data of
Bocheng Lei, Xiaobo Gao, Ran Zhang, Xin Yi, Qing Zhou   +4 more
doaj   +1 more source

Non-coding RNA delivery for bone tissue engineering: Progress, challenges, and potential solutions

iScience, 2022
Summary: More than 20 million individuals worldwide suffer from congenital or acquired bone defects annually. The development of bone scaffold materials that simulate natural bone for bone defect repair remains challenging.
Shiyao Guan, Zhen Zhang, Jun Wu
doaj   +1 more source

Recent advances of responsive scaffolds in bone tissue engineering

Frontiers in Bioengineering and Biotechnology, 2023
The investigation of bone defect repair has been a significant focus in clinical research. The gradual progress and utilization of different scaffolds for bone repair have been facilitated by advancements in material science and tissue engineering.
Tongyu Zhu, Hongbo Zhou, Xiaojing Chen, Yuanjing Zhu   +3 more
doaj   +1 more source

Applications of carbon dots and its modified carbon dots in bone defect repair

Journal of Biological Engineering, 2022
Bone defect repair is a continual and complicated process driven by a variety of variables. Because of its bright multicolor luminescence, superior biocompatibility, water dispersibility, and simplicity of synthesis from diverse carbon sources, carbon ...
Longchuan Zhu, Weijian Kong, Jijun Ma, Renfeng Zhang, Cheng Qin, Hao Liu, Su Pan   +6 more
doaj   +1 more source

Flavonoid-Loaded Biomaterials in Bone Defect Repair

Molecules, 2023
Skeletons play an important role in the human body, and can form gaps of varying sizes once damaged. Bone defect healing involves a series of complex physiological processes and requires ideal bone defect implants to accelerate bone defect healing ...
Jiali Yang, Lifeng Zhang, Qiteng Ding, Shuai Zhang, Shuwen Sun, Wencong Liu, Jinhui Liu, Xiao Han, Chuanbo Ding   +8 more
doaj   +1 more source

Efficient bone regeneration of BMP9-stimulated human periodontal ligament stem cells (hPDLSCs) in decellularized bone matrix (DBM) constructs to model maxillofacial intrabony defect repair

Stem Cell Research & Therapy, 2022
Background BMP9-stimulated DPSCs, SCAPs and PDLSCs are effective candidates for repairing maxillofacial bone defects in tissue engineering, while the most suitable seed cell source among these three hDMSCs and the optimal combination of most suitable ...
Yuxin Zhang, Wenping Luo, Liwen Zheng, Jing Hu, Li Nie, Huan Zeng, Xi Tan, Yucan Jiang, Yeming Li, Tianyu Zhao, Zhuohui Yang, Tong-Chuan He, Hongmei Zhang   +12 more
doaj   +1 more source