Results 271 to 280 of about 1,264,713 (295)

Targeting the bone microenvironment in multiple myeloma

Journal of Bone and Mineral Metabolism, 2010
Multiple myeloma (MM) is a plasma cell malignancy characterized by the frequent development of osteolytic lesions, osteopenia, pathological fractures, and/or severe bone pain. In the past few years several potential factors involved in this process have been identified and, with the increased knowledge of the signaling pathways involved in the ...
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The Bone Microenvironment in Prostate Cancer Metastasis

2019
The propensity of prostate cancer cells to seed the skeleton and then progress into clinically relevant metastatic tumors is widely recognized and a major cause of morbidity and mortality for patients. The natural history of prostate adenocarcinoma most frequently begins with a tumor diagnosed at a localized stage, which is successfully treated by ...
Anthony, DiNatale, Alessandro, Fatatis
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Leukemia and bone marrow microenvironment

STEM CELLS, 1994
S C, Gulati, B, Nath
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Novel approaches to target the microenvironment of bone metastasis

Nature Reviews Clinical Oncology, 2021
Klaus Pantel, Franz Jakob, Aline Bozec
exaly  

Piezoresistive MXene/Silk fibroin nanocomposite hydrogel for accelerating bone regeneration by Re-establishing electrical microenvironment

Bioactive Materials, 2023
Libo Jiang, Hai-Feng Liang, Di‐Han Su
exaly  

Androgen, Estrogen, and the Bone Marrow Microenvironment

2006
Abstract : In this project we plan to analyze androgen- and estrogen-responsive gene expression in the bone marrow. We plan to work to: determine if castration-induced gene expression changes in mouse bone marrow are caused by the deficiency of testosterone or estrogen; analyze androgen and estrogen-sensitive cytokine and gene expression changes in ...
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Bioprinted constructs that simulate nerve–bone crosstalk to improve microenvironment for bone repair

Bioactive Materials, 2023
Yuxin Zhang, Jinwu Wang, Lei Qiang
exaly  

Bone ECM-like 3D Printing Scaffold with Liquid Crystalline and Viscoelastic Microenvironment for Bone Regeneration

ACS Nano, 2022
Binghong Luo, Hong Li, Lu Lu
exaly  

Microenvironment-responsive nanocarriers for targeted bone disease therapy

Nano Today, 2023
Jiacan Su, Jin Cui, Sicheng Wang
exaly  

Immune microenvironment of cancer bone metastasis

Bone
Bone is a common and frequent site of metastasis in cancer patients, leading to a significant reduction in quality of life and increased mortality. Bone marrow, the primary site of hematopoiesis, also serves as both a primary and secondary lymphoid organ.
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