Results 1 to 10 of about 338,869 (357)

Effects of material properties of femoral hip components on bone remodeling [PDF]

open access: green, 1992
Bone loss around femoral hip stems is one of the problems threatening the long-term fixation of uncemented stems. Many believe that this phenomenon is caused by reduced stresses in the bone (stress shielding).
Harrie Weinans   +2 more
core   +12 more sources

Overexpression of the Ubiquitin Specific Proteases USP43, USP41, USP27x and USP6 in Osteosarcoma Cell Lines: Inhibition of Osteosarcoma Tumor Growth and Lung Metastasis Development by the USP Antagonist PR619

open access: yesCells, 2021
Osteosarcoma (OS) is the most common malignant bone tumor in children and teenagers. In many cases, such as poor response to treatment or the presence of metastases at diagnosis, the survival rate of patients remains very low. Although in the literature,
Mélanie Lavaud   +14 more
doaj   +1 more source

LIM Kinases in Osteosarcoma Development

open access: yesCells, 2021
Tumorigenesis is a long-term and multistage process that often leads to the formation of metastases. During this pathological course, two major events appear to be crucial: primary tumour growth and metastatic expansion. In this context, despite research
Régis Brion   +5 more
doaj   +1 more source

Pro-inflammatory effects of human apatite crystals extracted from patients suffering from calcific tendinopathy

open access: yesArthritis Research & Therapy, 2021
Background Calcific tendonitis of the rotator cuff is due to carbonated apatite deposits in the shoulder tendons. During the evolution of the disease, an acute inflammatory episode may occur leading to the disappearance of the calcification.
Julien Herman   +6 more
doaj   +1 more source

The Role of Osteocytes in Targeted Bone Remodeling: A Mathematical Model [PDF]

open access: yes, 2013
Until recently many studies of bone remodeling at the cellular level have focused on the behavior of mature osteoblasts and osteoclasts, and their respective precursor cells, with the role of osteocytes and bone lining cells left largely unexplored. This
Ayati, Bruce P.   +3 more
core   +6 more sources

Advances of exosomes in periodontitis treatment

open access: yesJournal of Translational Medicine, 2022
Periodontitis is an inflammatory disease initiated by dysbiosis of the local microbial community. Periodontitis can result in destruction of tooth-supporting tissue; however, overactivation of the host immune response is the main reason for alveolar bone
Hongbing Lin   +8 more
doaj   +1 more source

Cellular and molecular mediators of bone metastatic lesions [PDF]

open access: yes, 2018
Bone is the preferential site of metastasis for breast and prostate tumor. Cancer cells establish a tight relationship with the host tissue, secreting factors that stimulate or inhibit bone cells, receiving signals generated from the bone remodeling ...
Battafarano, Giulia   +3 more
core   +5 more sources

Effects of chronic stress caused by occlusal disorder on the body

open access: yes口腔疾病防治, 2020
Occlusal disorder is an abnormal condition in which the static and dynamic relations between the upper and lower teeth are not well aligned . The most common occlusal disorder in clinical practice is the inability to reach the intercuspal position due to
JIANG Jiayang   +6 more
doaj   +1 more source

Implication of the p53-Related miR-34c, -125b, and -203 in the Osteoblastic Differentiation and the Malignant Transformation of Bone Sarcomas

open access: yesCells, 2020
The formation of the skeleton occurs throughout the lives of vertebrates and is achieved through the balanced activities of two kinds of specialized bone cells: the bone-forming osteoblasts and the bone-resorbing osteoclasts. Impairment in the remodeling
Camille Jacques   +6 more
doaj   +1 more source

The impact of masticatory dysfunction caused by occlusal disharmony on cognitive function

open access: yes口腔疾病防治, 2021
As the world’s population ages, age-related cognitive decline and dementia are becoming important challenges for geriatric care. Despite the ongoing search for solutions to address cognitive decline, effective interventions have not yet been established.
OU Yanzhen   +5 more
doaj   +1 more source

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