Results 1 to 10 of about 2,011,561 (382)
The Smad Dependent TGF-β and BMP Signaling Pathway in Bone Remodeling and Therapies
Frontiers in Molecular Biosciences, 2021 Bone remodeling is a continuous process that maintains the homeostasis of the skeletal system, and it depends on the homeostasis between bone-forming osteoblasts and bone-absorbing osteoclasts.
Si-yu Liu, Xia Li, Feng-lai Yuan
exaly +2 more sources
Macrophages and Bone Remodeling
Journal of Bone and Mineral Research, 2023 Bone remodeling in the adult skeleton facilitates the removal and replacement of damaged and old bone to maintain bone quality. Tight coordination of bone resorption and bone formation during remodeling crucially maintains skeletal mass.
Megan M. Weivoda, E. Bradley
semanticscholar +3 more sources
Chemokines in Physiological and Pathological Bone Remodeling
Frontiers in Immunology, 2019 The bone matrix is constantly remodeled by bone-resorbing osteoclasts and bone-forming osteoblasts. These two cell types are fundamentally different in terms of progenitor cells, mode of action and regulation by specific molecules, acting either ...
Laura Brylka
exaly +2 more sources
Cancellous Bone Remodeling Occurs in Specialized Compartments Lined by Cells Expressing Osteoblastic Markers [PDF]
Journal of Bone and Mineral Research, 2001 Leif Mosekilde
exaly +2 more sources
Cells, 2021 Osteosarcoma (OS) is the most common malignant bone tumor in children and teenagers. In many cases, such as poor response to treatment or the presence of metastases at diagnosis, the survival rate of patients remains very low. Although in the literature,
Mélanie Lavaud +14 more
doaj +1 more source
The effect of cytokines on osteoblasts and osteoclasts in bone remodeling in osteoporosis: a review
Frontiers in Immunology, 2023 The complicated connections and cross talk between the skeletal system and the immune system are attracting more attention, which is developing into the field of Osteoimmunology.
Jie Xu, +4 more
semanticscholar +1 more source
Modulation of bone remodeling by the gut microbiota: a new therapy for osteoporosis
Bone Research, 2023 The gut microbiota (GM) plays a crucial role in maintaining the overall health and well-being of the host. Recent studies have demonstrated that the GM may significantly influence bone metabolism and degenerative skeletal diseases, such as osteoporosis ...
Zhengtian Lyu +3 more
semanticscholar +1 more source
Mechanical regulation of bone remodeling
Bone Research, 2022 Bone remodeling is a lifelong process that gives rise to a mature, dynamic bone structure via a balance between bone formation by osteoblasts and resorption by osteoclasts.
Lijun Wang +4 more
semanticscholar +1 more source
Bone remodeling: an operational process ensuring survival and bone mechanical competence
Bone Research, 2022 Bone remodeling replaces old and damaged bone with new bone through a sequence of cellular events occurring on the same surface without any change in bone shape.
S. Bolamperti, I. Villa, A. Rubinacci
semanticscholar +1 more source
LIM Kinases in Osteosarcoma Development
Cells, 2021 Tumorigenesis is a long-term and multistage process that often leads to the formation of metastases. During this pathological course, two major events appear to be crucial: primary tumour growth and metastatic expansion. In this context, despite research
Régis Brion +5 more
doaj +1 more source