Background: Snakebite envenomation (SBE) causes diverse toxic effects in humans, including disability and death. Current antivenom therapies effectively prevent death but fail to block local tissue damage, leading to an increase in the severity of ...
Camila Castro-Pinheiro +7 more
doaj +2 more sources
Light Emitting Diode Photobiomodulation Enhances Oxidative Redox Capacity in Murine Macrophages Stimulated with <i>Bothrops jararacussu</i> Venom and Isolated PLA<sub>2</sub>s. [PDF]
Photobiomodulation therapy associated with conventional antivenom treatment has been shown to be effective in reducing the local effects caused by bothropic venoms in preclinical studies. In this study, we analyzed the influence of photobiomodulation using light emitting diode (LED) on the oxidative stress produced by murine macrophages stimulated with
Dos Reis VP +9 more
europepmc +2 more sources
[Cross neutralization of bothrops jararacussu venom by heterologous antivenoms].
We have studied the immunochemical cross-reactivity and cross-neutralization of the lethal potency, hemorrhagic, necrotizing, procoagulant and (indirect) hemolytic activities of Bothrops jararacussu venom by the standard antivenoms produced in Argentina.
A R, de Roodt +6 more
openaire +2 more sources
Envenenamento experimental por Bothropoides jararaca e Bothrops jararacussu em ovinos: aspectos clínico-patológicos e laboratoriais Experimental poisoning by Bothropoides jararaca and Bothrops jararacussu in sheep: clinic-pathological and laboratory aspects [PDF]
Esse estudo teve como objetivo determinar as alterações clínico-patológicas e laboratoriais em ovinos inoculados com a peçonha de Bothropoides jararaca e Bothrops jararacussu, no intuito de fornecer subsídios que possam facilitar o estabelecimento do ...
Ana Paula Aragão +6 more
doaj +2 more sources
Hemiparesia esquerda consecutiva a empeçonhamento: Por Bothrops Jararacussu [PDF]
O A. apresenta uma observação de hemiparesia esquerda, consecutiva a envenenamento por Bothrops Jararacussu. É o segundo caso que publica, com idêntica etiologia; além das suas, há duas outras observações semelhantes, de Octávio de Magalhães.
Napoleão L. Teixeira
doaj +3 more sources
Heparin and commercial bothropic antivenom against the paralyzing effect of Bothrops jararacussu snake venom [PDF]
The crude venom of Bothrops jararacussu (Bjssu) is known to induce muscular paralysis in vitro. Many studies have shown that various substances, including heparin, neutralize the damage caused by snake venom. In the present study, the ability of heparin (
S Rostelato-Ferreira +2 more
doaj +4 more sources
Anurans or Mice: What is the Best Food Item for Young and Adults of Bothrops jararacussu (Lacerda, 1884) in Captivity? [PDF]
We use Bothrops jararacussu as a model to introduce three different prey items (mice, exotic anuran – bullfrog and native anurans) in captivity. Our experiments indicated that native anurans could be an interesting food alternative to B. jararacussu and other Bothrops species with an ontogenetic diet in captivity.
Torrents TV +3 more
europepmc +2 more sources
Antimicrobial peptidomes of Bothrops atrox and Bothrops jararacussu snake venoms [PDF]
The worrisome emergence of pathogens resistant to conventional drugs has stimulated the search for new classes of antimicrobial and antiparasitic agents from natural sources. Antimicrobial peptides (AMPs), acting through mechanisms that do not rely on the interaction with a specific receptor, provide new possibilities for the development of drugs ...
Cleópatra Alves da Silva Caldeira +10 more
openaire +4 more sources
Sequence of a cDNA encoding bothropstoxin I, a myotoxin from the venom of Bothrops jararacussu
With the aim of further understanding the structure/function relationships in the membrane-damaging activity of the Lys49 phospholipase A2 (Lys49-PLA2) sub-family, we used PCR (polymerase chain reaction) on total venom gland cDNAs from Bothrops jararacussu with degenerate oligodeoxyribonucleotides encoding the N- and C-termini of myotoxin II, a Lys49 ...
Ward, R. J. +4 more
openaire +4 more sources
Comparative Hemostatic Effects of <i>Bothrops</i> spp. and <i>Daboia russelii</i> Venoms. [PDF]
Venoms from Bothrops species and Daboia russelii are among the leading causes of venom‐induced coagulopathy and snakebite‐related deaths. In this study, we comparatively evaluated the biochemical composition and hemostatic effects of venoms from seven Bothrops species and D. russelii using protein profiling and functional coagulation assays.
Malchias-Pires GM +8 more
europepmc +2 more sources

