Results 71 to 80 of about 1,891 (175)

Hospital-acquired intestinal toxemia botulism in a newly diagnosed adult colon cancer patient

Revista do Instituto de Medicina Tropical de São Paulo
This manuscript reports a case of intestinal toxemia botulism in an adult with recently diagnosed metastatic colon cancer in whom botulism symptoms began 23 days after hospital admission.
Lucas José Sá da Fonseca, Diogo Couto de Carvalho, Helena Providelli de Moraes, Izabela Dayany França Feitosa, Gil Pereira Neto, Rodrigo Vasconcellos Vilela, Breno Franco Silveira Fernandes, Rodrigo Santiago Gomez, Vandack Nobre   +8 more
doaj   +1 more source

Foodborne botulism due to ingestion of home-canned green beans: two case reports

Journal of Medical Case Reports, 2018
Background Foodborne botulism is a life-threatening, rapidly progressive disease. It has an incidence of less than 10 cases per year in Germany and mostly affects several previously healthy people at the same time.
Dorothea Hellmich, Katja E. Wartenberg, Stephan Zierz, Tobias J. Mueller   +3 more
doaj   +1 more source

A rare symptom of foodborne botulism: dysgeusia. Case report and clinical review

Emergency Care Journal
Clostridium botulinum has become one of the most well-known microorganisms in medical history, thanks to both fatal botulism epidemics and the recent medical use of botulinum neurotoxin.
Simone Esposito, Francesco Coletta, Giovanna Di Maiolo, Filomena Lo Chiatto, Pasquale Rinaldi, Anna Lanza, Getano Panico, Crescenzo Sala, Antonio Tomasello, Romolo Villani   +9 more
doaj   +1 more source

A novel strategy for development of recombinant antitoxin therapeutics tested in a mouse botulism model.

PLoS ONE, 2012
Antitoxins are needed that can be produced economically with improved safety and shelf life compared to conventional antisera-based therapeutics. Here we report a practical strategy for development of simple antitoxin therapeutics with substantial ...
Jean Mukherjee, Jacqueline M Tremblay, Clinton E Leysath, Kwasi Ofori, Karen Baldwin, Xiaochuan Feng, Daniela Bedenice, Robert P Webb, Patrick M Wright, Leonard A Smith, Saul Tzipori, Charles B Shoemaker   +11 more
doaj   +1 more source

Investigational heptavalent botulinum antitoxin (HBAT) to replace licensed botulinum antitoxin AB and investigational botulinum antitoxin E.

MMWR. Morbidity and mortality weekly report, 2010
CDC announces the availability of a new heptavalent botulinum antitoxin (HBAT, Cangene Corporation) through a CDC-sponsored Food and Drug Administration (FDA) Investigational New Drug (IND) protocol. HBAT replaces a licensed bivalent botulinum antitoxin AB and an investigational monovalent botulinum antitoxin E (BAT-AB and BAT-E, Sanofi Pasteur) with ...
openaire   +1 more source

Four Cases of Food-Borne Botulism in a Family

پزشکی بالینی ابن سینا, 2002
Botulism is caused  by a neurotoxin produced from the anaerobic,    Spore-forming bacterium clostridium botulinum. Botulism have four     clinical  forms:1)Food –borne botulism   2)Wound botulism    3)Infant botulism    4)undetermined botulism, that the 
Fariba Keramat
doaj  

Role of Homologous Fc Fragment in the Potency and Efficacy of Anti‐Botulinum Antibody Preparations

Toxins, 2017
The only approved treatment for botulism relies on passive immunity which is mostly based on antibody preparations collected from hyper‐immune horses. The IgG Fc fragment is commonly removed from these heterologous preparations to reduce the incidence of
Amram Torgeman, Eyal Ozeri, Alon Ben David, Eran Diamant, Osnat Rosen, Arieh Schwartz, Ada Barnea, Arik Makovitzki, Avishai Mimran, Ran Zichel   +9 more
doaj   +1 more source

Production of monoclonal antibodies against botulinum neurotoxin in Nicotiana benthamiana

Human Vaccines & Immunotherapeutics
Botulism is a fatal neurologic disease caused by the botulinum toxin (BoNT) produced by Clostridium botulinum. It is a rare but highly toxic disease with symptoms, such as cramps, nausea, vomiting, diarrhea, dysphagia, respiratory failure, muscle ...
Kornchanok Sangprasat, Christine Joy I. Bulaon, Kaewta Rattanapisit, Theerakarn Srisangsung, Perawat Jirarojwattana, Apidsada Wongwatanasin, Waranyoo Phoolcharoen   +6 more
doaj   +1 more source

Cranial Neuropathies and Neuromuscular Weakness: A Case of Mistaken Identity

Clinical Practice and Cases in Emergency Medicine, 2017
We describe a case of wound botulism initially thought to represent Miller-Fisher variant Guillain-Barré syndrome (MFS). Botulism classically presents with the so-called “four D’s” (diplopia, dysarthria, dysphagia, dry mouth) with symmetric, descending ...
Daniel Z. Adams, Andrew King, Colin Kaide   +2 more
doaj   +1 more source

Cost savings associated with timely treatment of botulism with botulism antitoxin heptavalent product.

PLoS ONE, 2019
BACKGROUND:Botulism is a rare, serious, and sometimes fatal paralytic illness caused by exposure to neurotoxins produced by Clostridium botulinum bacteria.
Deborah M Anderson, Veena R Kumar, Diana L Arper, Eliza Kruger, S Pinar Bilir, Jason S Richardson   +5 more
doaj   +1 more source