Results 151 to 160 of about 83,600 (312)

Safety and Pharmacokinetics of a Four Monoclonal Antibody Combination Against Botulinum C and D Neurotoxins. [PDF]

, 2019
Botulism is caused by botulinum neurotoxin (BoNT), the most poisonous substance known. BoNTs are also classified as Tier 1 biothreat agents due to their high potency and lethality.
Cobb, Ronald R, Conrad, Fraser, Espinoza, Yero, Garcia-Rodriguez, Consuelo, Kimbler, Angie, Kraus, Carl N, Marks, James D, Martinez, Zachary, Pham, Khanh, Riling, Kathryn, Snow, Doris M, Tomic, Milan T, Wong, David   +12 more
core  

Immunological characterization of papain-induced fragments of Clostridium botulinum type A neurotoxin and interaction of the fragments with brain synaptosomes [PDF]

, 1989
S Kozaki, Asami Miki, Yoichi Kamata, Junetsu Ogasawara, Genji Sakaguchi   +4 more
openalex   +1 more source

Negative effects of submandibular botulinum neurotoxin A injections on oral motor function in children with drooling due to central nervous system disorders

Developmental Medicine & Child Neurology, 2017
The aims of this study were: (1) to determine the incidence and nature of adverse effects on oral motor function after first injections of botulinum neurotoxin A (BoNT‐A) in submandibular glands for excessive drooling in children with central nervous ...
K. Hulst, Carlyn V. Kouwenberg, P. Jongerius, T. Feuth, F. Hoogen, A. Geurts, C. Erasmus   +6 more
semanticscholar   +1 more source

Molecular cloning of the Clostridium botulinum structural gene encoding the type B neurotoxin and determination of its entire nucleotide sequence [PDF]

, 1992
Sarah M. Whelan, Michael J. Elmore, Nicola J. Bodsworth, John K. Brehm, Tony Atkinson, Nigel P. Minton   +5 more
openalex   +1 more source

Subacute Painful Axonal Polyneuropathy Associated with Foslevodopa/Foscarbidopa Subcutaneous Infusion in Advanced Parkinson's Disease

Movement Disorders, EarlyView.
Aukusti Valli, Filip Scheperjans
wiley   +1 more source

Changes in Glenohumeral Musculoskeletal Development Following Brachial Plexus Birth Injury

Journal of Orthopaedic Research, Volume 43, Issue 8, Page 1367-1377, August 2025.
ABSTRACT Brachial plexus birth injury (BPBI), one of the most common nerve injuries in children, often leads to impaired shoulder development, resulting in sustained postural and bone deformity and muscle weakness. Despite the substantial long‐term consequences, clinical consensus is lacking for what BPBI treatments are optimal in terms of timing and ...
Emily B. Fawcett, Kyla B. Bosh, Katherine R. Saul, Jacqueline H. Cole   +3 more
wiley   +1 more source

Neurotropic Effect of Botulinum Toxin and the Potential of Specific Serum Therapy in Botulism (Review)

Безопасность и риск фармакотерапии
INTRODUCTION. The outbreak of foodborne botulism that occurred in Russia in June 2024 once again demonstrated the danger of this rather rare but severe infectious disease caused by ingesting botulinum neurotoxin.
E. M. Eliseeva, I. A. Mazerkina, A. A. Chistokhina   +2 more
doaj   +1 more source

Molecular Mechanisms of Chronic Pain and Therapeutic Interventions

MedComm, Volume 6, Issue 8, August 2025.
We offer a comprehensive overview of the distinctive molecular mechanisms underlying nociceptive, neuropathic, and nociplastic pain, including the immune responses, ion channels, monoaminergic imbalance, and neuroinflammation. Subsequently, we summarized the status quo of nociceptive, neuropathic, and nociplastic pain managementmanipulation.
Zhen Li, Xing Li, Jieqiong Liu, Rao Sun, Yingze Ye, Hongbing Xiang, Fang Luo, Shiyong Li, Ailin Luo   +8 more
wiley   +1 more source

Nucleotide sequence ofClostridium botulinumC1 neurotoxin [PDF]

, 1990
Daniel Hauser, Melvin W. Eklund, Hisao Kurazono, Thomas Binz, Heiner Niemann, D. Michael Gill, Patrice Boquet, Michel R. Popoff   +7 more
openalex   +1 more source

Radiolabeled Nanogels: From Multimodality Imaging to Combination Therapy of Cancer

Small Science, Volume 5, Issue 8, August 2025.
Nanogel refers to nanosized particles formed by physical or chemical crosslinking of polymers. Rational design and refinement of nanogel properties are imperative to unlock their full potential, ensuring tailored solutions for personalized cancer management. This review elucidates the transformative potential of radiolabeled nanogels in revolutionizing
Sanchita Ghosh, Weibo Cai, Rubel Chakravarty   +2 more
wiley   +1 more source