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2020
Clostridium botulinum is an anaerobic, gram-positive bacterium that secretes an extremely large neurotoxic molecule (900 kDa), which produces food poisoning or botulism. It is now also used in medicine to treat diseases according to Paracelsus's paradigm that the difference between a poison and a drug lies in the dose.
Signorini, Massimo +5 more
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Clostridium botulinum is an anaerobic, gram-positive bacterium that secretes an extremely large neurotoxic molecule (900 kDa), which produces food poisoning or botulism. It is now also used in medicine to treat diseases according to Paracelsus's paradigm that the difference between a poison and a drug lies in the dose.
Signorini, Massimo +5 more
openaire +2 more sources
Botulinum B Toxin as an Alternative to Botulinum A Toxin
Ophthalmic Plastic & Reconstructive Surgery, 1993Histochemical effects of botulinum B toxin were studied on fibers from longissimus dorsi muscle in Albino rabbits and compared to effects produced by botulinum A toxin. Acetylcholinesterase staining, muscle fiber size analysis, and ATPase staining indicated botulinum B toxin produced a denervation gradient and field similar to that produced by ...
G E, Borodic +4 more
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Journal of American Academy of Dermatology, 2019
Hyperhidrosis is a dermatological condition defined by excessive sweating beyond thermoregulatory needs with significant effects on patients' quality of life. Hyperhidrosis is categorized as primary or secondary: primary hyperhidrosis is mostly focal and
S. Nawrocki, Jisun Cha
semanticscholar +1 more source
Hyperhidrosis is a dermatological condition defined by excessive sweating beyond thermoregulatory needs with significant effects on patients' quality of life. Hyperhidrosis is categorized as primary or secondary: primary hyperhidrosis is mostly focal and
S. Nawrocki, Jisun Cha
semanticscholar +1 more source
Botulinum Toxin Injections for Masseter Reduction in East Asians
Dermatologic Surgery, 2019BACKGROUND Cultural ideals for a slimmer face have led to an upsurge in interest in facial contouring among East Asians. Although surgical resection has traditionally been the main treatment option, botulinum toxin injection is becoming a popular ...
Judy Cheng, S. Hsu, J. McGee
semanticscholar +1 more source
Plastic and Reconstructive Surgery, 2019
BACKGROUND Postoperative hypertrophic scarring of the medial canthal area is a common phenomenon and deterrent for patients considering epicanthoplasty. Botulinum toxin type A has been reported for hypertrophic scar and keloid treatment.
Ru-Lin Huang +5 more
semanticscholar +1 more source
BACKGROUND Postoperative hypertrophic scarring of the medial canthal area is a common phenomenon and deterrent for patients considering epicanthoplasty. Botulinum toxin type A has been reported for hypertrophic scar and keloid treatment.
Ru-Lin Huang +5 more
semanticscholar +1 more source
Critical Care Clinics, 2005
Botulinum toxin is regarded as the most lethal substance known. It is estimated that the human LD50 for inhalation botulism is 1 to 3 nanograms of toxin/kilogram body mass. Although only three cases of inhalational botulism have been described, an understanding of the pathophysiology of food-borne outbreaks, wound botulism, and infant botulism, and ...
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Botulinum toxin is regarded as the most lethal substance known. It is estimated that the human LD50 for inhalation botulism is 1 to 3 nanograms of toxin/kilogram body mass. Although only three cases of inhalational botulism have been described, an understanding of the pathophysiology of food-borne outbreaks, wound botulism, and infant botulism, and ...
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Pharmacology of botulinum toxin
Journal of the American Academy of Dermatology, 2000Botulinum toxin has a well-defined role among dermatologists for the treatment of facial wrinkling, brow position, and palmar and axillary hyperhidrosis.The purpose of this study is to educate dermatologists on the pharmacology of botulinum toxin.A retrospective review of the literature on botulinum toxin from 1962 to the present was conducted.
W, Huang, J A, Foster, A S, Rogachefsky
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Dermatologic Surgery, 2000
Botulinum toxin has been used successfully for the treatment of hyperfunctional facial lines.To determine the alteration in brow position after botulinum toxin treatment of the brow depressor muscles.Eleven women, 30-60 years old, were treated. Prior to treatment, brow position was measured relative to the pupil.
W, Huang, A S, Rogachefsky, J A, Foster
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Botulinum toxin has been used successfully for the treatment of hyperfunctional facial lines.To determine the alteration in brow position after botulinum toxin treatment of the brow depressor muscles.Eleven women, 30-60 years old, were treated. Prior to treatment, brow position was measured relative to the pupil.
W, Huang, A S, Rogachefsky, J A, Foster
openaire +2 more sources
Innovation in Botulinum Toxins
Dermatologic ClinicsThis study aims to analyze and discuss recent trials of high-dose and liquid toxins for treating moderate to severe glabellar lines. A comprehensive review of clinical studies and patient outcomes data was conducted to assess the effectiveness and safety profiles of high-dose and liquid toxins.
Reema, Rashied, Michael H, Gold
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American Journal of Physical Medicine & Rehabilitation, 2004
In the United States, the popularity of botulinum toxins as agents to treat muscle hypertonia has grown significantly over the last decade, despite lack of approval from the Food and Drug Administration for the indication of spasticity. Botox (botulinum toxin type A) and Myobloc (botulinum toxin type B) are Food and Drug Administration-approved for ...
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In the United States, the popularity of botulinum toxins as agents to treat muscle hypertonia has grown significantly over the last decade, despite lack of approval from the Food and Drug Administration for the indication of spasticity. Botox (botulinum toxin type A) and Myobloc (botulinum toxin type B) are Food and Drug Administration-approved for ...
openaire +2 more sources