Results 1 to 10 of about 117,034 (131)

High resolution genome-wide SNP array analyses on matched colorectal-based lung and brain metastases [PDF]

Journal of Cancer Research and Clinical Oncology
Purpose Colorectal-based brain metastasis formation is a rare and late event in colorectal cancer (CRC) patients and is associated with poor survival.
Vivian-Pascal Brandt, Carolin Sander, Lydia Holland, Ronald Koschny, Wolf C. Müller, Hendrik Bläker, Ulf Nestler, Erdem Güresir, Heidrun Holland   +8 more
doaj   +2 more sources

Microenvironment and the progress of immunotherapy in clinical practice of NSCLC brain metastasis

Frontiers in Oncology, 2023
One of the most frequent distant metastases of lung cancer occurs in the brain. The average natural survival duration for patients with lung cancer who have brain metastases is about 1 to 2 months. Knowledge about brain metastases is currently restricted
Mengqing Xie, Chunxia Su
doaj   +1 more source

Association of Brain Metastases With Immune Checkpoint Inhibitors Efficacy in Advanced Lung Cancer: A Systematic Review and Meta-Analysis

Frontiers in Oncology, 2021
BackgroundIn pivotal immunotherapy trials, the efficacy of immune checkpoint inhibitors as treatments for lung cancer patients with brain metastases remains controversial.
Yanning Wang, Qianning Zhang, Chuansheng Chen, Yuxuan Hu, Liyun Miao, Yujie Zhou   +5 more
doaj   +1 more source

The effectiveness of chemotherapy in breast cancer patients with brain metastases [PDF]

Korean Journal of Clinical Oncology, 2014
Purpose: Treatments of brain metastases in breast cancer include whole brain radiotherapy, surgery, stereotactic radiosurgery, and systemic chemotherapy.
Won Cheol Chang, Yong Hwa Eom, So Hee Lee, Byung Joo Chae, Byung Joo Song, Sang Seol Jung   +5 more
doaj   +1 more source

New Artificial Intelligence Score and Immune Infiltrates as Prognostic Factors in Colorectal Cancer With Brain Metastases

Frontiers in Immunology, 2021
Incidence of brain metastases has increased in patients with colorectal cancer (CRC) as their survival has improved. CD3 T-cells and, lately, DGMate (DiGital tuMor pArameTErs) score, have been identified as prognostic factors in locally advanced CRC ...
Violaine Randrian, Violaine Randrian, Amandine Desette, Amandine Desette, Sheik Emambux, Sheik Emambux, Valentin Derangere, Pauline Roussille, Eric Frouin, Eric Frouin, Julie Godet, Lucie Karayan-Tapon, Lucie Karayan-Tapon, Lucie Karayan-Tapon, François Ghiringhelli, François Ghiringhelli, David Tougeron, David Tougeron   +17 more
doaj   +1 more source

Brain Metastases from Gynecologic Malignancies

Medicina, 2022
Background and Objectives: To present a series of brain metastases from gynecologic primaries and provide a summary of the relevant literature. Materials and Methods: We retrospectively review 18 patients with histologically confirmed brain metastases ...
Georgia Karpathiou, Florian Camy, Céline Chauleur, Maroa Dridi, Pierre Dal Col, Michel Peoc’h   +5 more
doaj   +1 more source

The risk and prognostic factors for brain metastases in esophageal cancer patients: an analysis of the SEER database

BMC Cancer, 2021
Background Brain metastases were rare in esophageal cancer patients. Using the Surveillance, Epidemiology, and End Results (SEER) database, the present study investigated the incidence, risk and prognostic factors of brain metastases in esophageal cancer
Shizhao Cheng, Lei Yang, Xin Dai, Jing Wang, Xingpeng Han   +4 more
doaj   +1 more source

Immune dysfunction revealed by digital spatial profiling of immuno-oncology markers in progressive stages of renal cell carcinoma and in brain metastases

Journal for ImmunoTherapy of Cancer, 2023
Background The tumor microenvironment (TME) contributes to cancer progression and treatment response to therapy, including in renal cell carcinoma (RCC).
Wei Wei, Michael Hurwitz, Sabina Signoretti, Lucia Jilaveanu, Toni K Choueiri, David L Rimm, Adebowale Adeniran, Sandra Martínez, Harriet M Kluger, David A Schoenfeld, Myrto Moutafi, Dijana Djureinovic, Ross D Merkin, David A Braun, Fabio Parisi   +14 more
doaj   +1 more source

Serum Biomarkers Associated with Clinical Outcomes Fail to Predict Brain Metastases in Patients with Stage IV Non-Small Cell Lung Cancers. [PDF]

PLoS ONE, 2016
Lung cancers account for the majority of brain metastases which pose major therapeutic challenges. Biomarkers prognosticating for the development of brain metastases in patients with non-small cell lung cancers (NSCLC) may improve personalized care.
Bob T Li, Emil Lou, Meier Hsu, Helena A Yu, Jarushka Naidoo, Marjorie G Zauderer, Camelia Sima, Melissa L Johnson, Mariza Daras, Lisa M DeAngelis, Martin Fleisher, Mark G Kris, Christopher G Azzoli   +12 more
doaj   +1 more source

Differential Distribution of Brain Metastases from Non-Small Cell Lung Cancer Based on Mutation Status

Brain Sciences, 2023
Non-small cell lung cancer (NSCLC) has a high rate of brain metastasis. The purpose of this study was to assess the differential distribution of brain metastases from primary NSCLC based on mutation status.
Bihong T. Chen, Taihao Jin, Ningrong Ye, Sean W. Chen, Russell C. Rockne, Stephanie Yoon, Isa Mambetsariev, Ebenezer Daniel, Ravi Salgia   +8 more
doaj   +1 more source