Results 11 to 20 of about 117,034 (131)
Nature Reviews Disease Primers, 2019 An estimated 20% of all patients with cancer will develop brain metastases, with the majority of brain metastases occurring in those with lung, breast and colorectal cancers, melanoma or renal cell carcinoma. Brain metastases are thought to occur via seeding of circulating tumour cells into the brain microvasculature; within this unique ...
Achrol, Achal Singh +10 more
+7 more sources
Clinical Medicine, 2014 Brain metastases are the most frequent neurological complication of cancer and the most common brain tumour type. Lung and breast cancers, and melanoma are responsible for up to three-quarters of metastatic brain lesions. Most patients exhibit either headache, seizures, focal deficits, cognitive or gait disorders, which severely impair the quality of ...
Jaime, Gállego Pérez-Larraya +1 more
openaire +4 more sources
OncoImmunology, 2022 Nearly 40% of the advanced cancer patients will present brain metastases during the course of their disease, with a 2-year life expectancy of less than 10%.
Alberto Carretero-González +8 more
doaj +1 more source
Ecancermedicalscience, 2012 Brain metastases are the most common neurologic complication related to systemic cancer. With continued improvements in systemic treatment, the incidence is expected to increase. This article reviews the clinical presentation, pathophysiology, prognostic factors, and treatment of metastatic brain tumors.Brain metastases from systemic cancer are up to ...
Christine, Lu-Emerson, April F, Eichler
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Value of screening and follow‐up brain MRI scans in patients with metastatic melanoma
Cancer Medicine, 2021 Background Novel treatments make long‐term survival possible for subsets of patients with melanoma brain metastases. Brain magnetic resonance imaging (MRI) may aid in early detection of brain metastases and inform treatment decisions. This study aimed to
Annemarie C. Eggen +7 more
doaj +1 more source
Outcome of Patients with Non-Small Cell Lung Cancer (NSCLC) and Brain Metastases: Egyptian Experience [PDF]
Research in Oncology, 2016 Background: Lung cancer remains the most common primary tumor responsible for brain metastases making up to 40% to 50% of cases. Brain metastases from NSCLC is associated with poor prognosis. Aim: The aim of this study is to analyze the risk factors and
Salah Elmesidy +5 more
doaj +1 more source
Unveiling the tumor immune microenvironment of organ-specific melanoma metastatic sites
Journal for ImmunoTherapy of Cancer, 2022 Background The liver is a known site of resistance to immunotherapy and the presence of liver metastases is associated with shorter progression-free and overall survival (OS) in melanoma, while lung metastases have been associated with a more favorable ...
John F Thompson +17 more
doaj +1 more source
Characterization of the immune microenvironment in brain metastases from different solid tumors
Cancer Medicine, 2020 Background Brain metastases are one of the most common intracranial neoplasms. Increasing evidence have indicated that systemic immunotherapy may provide long‐term benefits for brain metastases.
Jinling Jiang +13 more
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Longitudinal MRI evaluation of intracranial development and vascular characteristics of breast cancer brain metastases in a mouse model. [PDF]
PLoS ONE, 2013 Longitudinal MRI was applied to monitor intracranial initiation and development of brain metastases and assess tumor vascular volume and permeability in a mouse model of breast cancer brain metastases.
Heling Zhou, Min Chen, Dawen Zhao
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Small vessel ischemic disease of the brain and brain metastases in lung cancer patients. [PDF]
PLoS ONE, 2009 Brain metastases occur commonly in patients with lung cancer. Small vessel ischemic disease is frequently found when imaging the brain to detect metastases.
Peter J Mazzone +7 more
doaj +1 more source