Results 21 to 30 of about 117,034 (131)

Immune suppressive microenvironment in brain metastatic non-small cell lung cancer: comprehensive immune microenvironment profiling of brain metastases versus paired primary lung tumors (GASTO 1060)

OncoImmunology, 2022
Lung cancer is one of the most common causes of brain metastases and is always associated with poor prognosis. We investigated the immunophenotypes of primary lung tumors and paired brain metastases, as well as immunophenotypes in the synchronous group ...
Meichen Li, Xue Hou, Ke Sai, Lihong Wu, Jing Chen, Baishen Zhang, Na Wang, Lijia Wu, Hongbo Zheng, Jiao Zhang, Yonggao Mou, Likun Chen   +11 more
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Brain and spinal cord metastases with seminoma: A case report

IJU Case Reports, 2022
Introduction Brain and spinal cord metastases from testicular cancer occur rarely, and metastases with seminoma are extremely rare. Case presentation A 42‐year‐old man who was diagnosed with seminoma and multiple metastases underwent first‐line and ...
Tetsuya Yumioka, Shuichi Morizane, Karen Makishima, Tadashi Adachi, Emika Moriyasu, Hideto Iwamoto, Katsuya Hikita, Masashi Honda, Yoshihisa Umekita, Atsushi Takenaka   +9 more
doaj   +1 more source

Revisiting Indications for Brain Imaging During the Clinical Staging Evaluation of Lung Cancer

JTO Clinical and Research Reports, 2022
Introduction: Available guidelines are inconsistent as to whether patients with newly diagnosed clinical stage II NSCLC should receive routine brain imaging.
Matthew D. Pichert, MD, Maureen E. Canavan, PhD, MPH, Richard C. Maduka, MD, Andrew X. Li, MD, Theresa Ermer, MD, Peter L. Zhan, MD, Michael Kaminski, BA, Brooks V. Udelsman, MD, MHS, Justin D. Blasberg, MD, MPH, Vincent J. Mase, Jr., MD, Andrew P. Dhanasopon, MD, Daniel J. Boffa, MD, MBA   +11 more
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Dynamic contrast‐enhanced MRI perfusion for differentiating between melanoma and lung cancer brain metastases

Cancer Medicine, 2017
Brain metastases originating from different primary sites overlap in appearance and are difficult to differentiate with conventional MRI. Dynamic contrast‐enhanced (DCE)‐MRI can assess tumor microvasculature and has demonstrated utility in characterizing
Vaios Hatzoglou, Jamie Tisnado, Alpesh Mehta, Kyung K. Peck, Mariza Daras, Antonio M. Omuro, Kathryn Beal, Andrei I. Holodny   +7 more
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Incidence and gender difference of brain metastases in newly diagnosed follicular thyroid cancer patients

European Thyroid Journal
Background: Population-based estimates of brain metastases in follicular thyroid cancer (FTC) patients with or without distant metastases (DMs) at diagnosis are lacking.
Ruiguo Zhang, Weijian Li, Hui Wang, Wenxin Zhang, Jinyan Chai, Pengpeng Chang, Qiang Jia, Wei Zheng   +7 more
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Identification of CD37, cystatin A, and IL-23A gene expression in association with brain metastasis: analysis of a prospective trial

The International Journal of Biological Markers, 2019
Purpose/Objectives: We aimed to assess the predictive value of a lung cancer gene panel for the development of brain metastases. Materials/Methods: Between 2011 and 2015, 102 patients with lung cancer were prospectively enrolled in a clinical trial in ...
Ammoren Dohm, Jing Su, Emory R. McTyre, James M. Taylor, Lance D. Miller, W. Jeffrey Petty, Fei Xing, Hui-Wen Lo, Linda J. Metheny-Barlow, Stacey O’Neill, Christina Bellinger, Travis Dotson, Boris Pasche, Kounosuke Watabe, Michael D. Chan, Jimmy Ruiz   +15 more
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Serial monitoring of cerebrospinal fluid in patients with leptomeningeal metastases in lung cancer via the Ommaya reservoir as a predictive indicator of therapeutic efficacy and clinical prognosis

npj Precision Oncology
Leptomeningeal metastasis (LM) is a severe neurological complication in patients with lung adenocarcinoma (LUAD), typically indicating terminal stage and poor survival.
Hehui Fang, Haitao Luo, Shujin Li, Naimeng Yan, Shu Xu, Na Liu, Xiaoyue Wang, Ting Xu, Wanwan Cheng, Yong Liu, Chuanyong Yu, Shencun Fang   +11 more
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Mutational signatures of synchronous and metachronous brain metastases from lung adenocarcinoma

Experimental Hematology & Oncology, 2023
Brain metastasis (BM) is an important cause of mortality for cancer patients. Many patients were diagnosed with brain metastases at their first visit who have not received any treatment while a subset of patients did not have distant metastases at the ...
Jianing Chen, Hainan Yang, Chao Zhao, Tao Lin, Da Liu, Weiping Hong, Changguo Shan, Cheng Zhou, Ling Bao, Caicun Zhou, Linbo Cai, Chunxia Su, Zhaoming Zhou, Lei Wen   +13 more
doaj   +1 more source

The Risk of Hippocampal Metastasis and the Associated High-Risk Factors in 411 Patients With Brain Metastases

Frontiers in Oncology, 2022
Background and AimsTo retrospectively analyze the incidence of hippocampal metastasis and the associated high-risk factors in patients with brain metastases and evaluate the safety of hippocampal avoidance whole-brain radiation therapy (HA-WBRT ...
Peng Xie, Hui Qiao, Huiling Hu, Wenlong Xin, Huanyu Zhang, Ning Lan, Xiaohua Chen, Yan Ma   +7 more
doaj   +1 more source

Survival Outcomes of Local Compared With Systemic First Treatment of Non-Small Cell Lung Cancer Brain Metastases

Frontiers in Oncology, 2021
ObjectiveThis retrospective study evaluated the survival advantage of local treatment targeted to brain metastases, relative to systemic therapy, as the first option for brain metastases of non-small cell lung cancer (NSCLC).MethodsFirst reviewed were ...
Hong-Mei Liu, Hong-Mei Liu, Chun-Liu Meng, Lu-Jun Zhao   +3 more
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