Results 31 to 40 of about 117,034 (131)

Efficacy of Immune Checkpoint Inhibitors in Non-small-cell Lung Cancer Patients With Different Metastatic Sites: A Systematic Review and Meta-Analysis

Frontiers in Oncology, 2020
Background: Organ-specific response patterns reported in previous studies indicate different response toward immune checkpoint inhibitors (ICIs) in non-small-cell lung cancer (NSCLC) patients with different metastatic sites.
Kaili Yang, Jiarui Li, Chunmei Bai, Zhao Sun, Lin Zhao   +4 more
doaj   +1 more source

Genomic landscape of the immune microenvironments of brain metastases in breast cancer

Journal of Translational Medicine, 2020
Background This study was intended to investigate the genomic landscape of the immune microenvironments of brain metastases in breast cancer. Methods Three gene expression profile datasets (GSE76714, GSE125989 and GSE43837) of breast cancer with brain ...
Wei-cheng Lu, Hui Xie, Ce Yuan, Jin-jiang Li, Zhao-yang Li, An-hua Wu   +5 more
doaj   +1 more source

Antibody-Drug Conjugates as a Potential a Systemic Treatment Strategy for Brain Metastases in Cases of Solid Tumors

Journal of Oncological Sciences
Large molecular antibody-drug conjugates (ADCs) are able to easily access the site of metastasis in the brain due to the edematous structure of brain metastases, facilitating considerably high concentrations of the cytotoxic component of these ADCs in ...
Didem DİVRİKLİOĞLU, İsmail BAYRAKÇI, Erkan ÖZCAN, İrfan ÇİÇİN   +3 more
doaj   +1 more source

Therapy of breast cancer brain metastases: challenges, emerging treatments and perspectives

Therapeutic Advances in Medical Oncology, 2018
Brain metastases are the most common central nervous system tumors in adults, and incidence of brain metastases is increasing due to both improved diagnostic techniques (e.g.
Nuria Kotecki, Florence Lefranc, Daniel Devriendt, Ahmad Awada   +3 more
doaj   +1 more source

Extrathoracic Metastases in Pleural Mesothelioma

JTO Clinical and Research Reports, 2023
Introduction: Guidelines recommend obtaining a computed tomography scan of the chest for the staging of pleural mesothelioma and for assessing response to treatment.
Ibiayi Dagogo-Jack, MD, Beow Y. Yeap, ScD, Mari Mino-Kenudson, MD, Subba R. Digumarthy, MD   +3 more
doaj   +1 more source

Alterations of functional and structural connectivity in patients with brain metastases.

PLoS ONE, 2020
Metastases are the most prevalent tumors in the brain and are commonly associated with high morbidity and mortality. Previous studies have suggested that brain tumors can induce a loss of functional connectivity and alter the brain network architecture ...
Bo Hua, Xin Ding, Minghua Xiong, Fanyu Zhang, Yi Luo, Jurong Ding, Zhongxiang Ding   +6 more
doaj   +1 more source

Comparison of Tumor Microenvironments Between Primary Tumors and Brain Metastases in Patients With NSCLC

JTO Clinical and Research Reports, 2021
Introduction: This study investigates the immune profile of the primary lung tumors and the corresponding brain metastasis from patients with NSCLC using multiplex fluorescence immunohistochemistry.
Daiki Ikarashi, MD, PhD, Tamio Okimoto, MD, PhD, Takehito Shukuya, MD, PhD, Hiroko Onagi, MD, Takuo Hayashi, MD, PhD, Sara L. Sinicropi-Yao, PhD, Joseph M. Amann, PhD, Tetsuya Nakatsura, MD, PhD, Shigehisa Kitano, MD, PhD, David P. Carbone, MD, PhD   +9 more
doaj   +1 more source

Radiosurgery for Five to Fifteen Brain Metastases: A Single Centre Experience and a Review of the Literature

Frontiers in Oncology, 2022
PurposeStereotactic radiosurgery (SRS) is now mainstream for patients with 1-4 brain metastases however the management of patients with 5 or more brain metastases remains controversial.
Susanne J. Rogers, Nicoletta Lomax, Sara Alonso, Tessa Lazeroms, Oliver Riesterer   +4 more
doaj   +1 more source

Cystic brain metastases had slower speed of tumor shrinkage but similar prognosis compared with solid tumors that underwent radiosurgery treatment

Cancer Management and Research, 2019
Hui Wang,* Xiaoye Liu,* Xuechao Jiang, Yongchun Song, Xiaoguang Wang, Jingsheng Wang, Yang Dong, Fengtong Li, Zhiqiang Wu, Yuhan Zhang, Zhiyong Yuan Department of Radiation Oncology, Tianjin Medical University Cancer Institute and Hospital, National ...
Wang H, Liu X, Jiang X, Song Y, Wang X, Wang J, Dong Y, Li F, Wu Z, Zhang Y, Yuan Z   +10 more
doaj  

Comparison of whole brain radiation therapy for synchronous brain metastases with irradiation protecting the hippocampus versus whole brain radiotherapy for sequential brain metastases to boost irradiation in the treatment of brain metastases from SCLC: study protocol for a randomized controlled trial

Trials, 2022
Background This study is in regard to the comparison of whole brain radiation therapy for synchronous brain metastases with irradiation protecting the hippocampus versus whole brain radiotherapy for sequential brain metastases to boost irradiation in the
Xiaofang Zhang, Tianlu Wang, Chen Yu Wang, Peng Zhao, Bo Huang, Lei He, Ying Qiu Song   +6 more
doaj   +1 more source