Results 41 to 50 of about 117,034 (131)

Clinical presentation of brain metastases from endometrial carcinoma: A case series

Gynecologic Oncology Reports, 2019
Brain metastases from endometrial carcinoma are rare, however they do occur, and they are associated with an especially poor prognosis. There is evidence demonstrating improved outcomes with early diagnosis and subsequent multimodal treatment. This study
Marisa R. Moroney, Lindsay J. Wheeler, Bradley R. Corr   +2 more
doaj   +1 more source

Effect of whole-brain radiotherapy with platinum-based chemotherapy in non-small cell lung cancer patients with multiple metastases including brain metastases

Scientific Reports, 2023
Current guidelines recommend that cytotoxic chemotherapy be considered first in non-small cell lung cancer (NSCLC) patients with multiple metastases, and whole-brain radiotherapy (WBRT) is not initially recommended even if brain metastases are present ...
Woo Kyung Ryu, Hyung Keun Cha, Woochul Kim, Ha Young Lee, Hyun-Jung Kim, Jeong-Seon Ryu, Jun Hyeok Lim   +6 more
doaj   +1 more source

Advances in Bevacizumab Therapy for Non-small Cell Lung Cancer 
with Brain Metastases

Chinese Journal of Lung Cancer, 2016
Brain metastases are frequently encountered in patients with non-small cell lung cancer (NSCLC) and are a significant cause of morbidity and mortality.
Liyan QU, Rui GENG, Xia SONG
doaj   +1 more source

Understanding the heterogeneous immune repertoire of brain metastases for designing next‐gen therapeutics

Brain-X, 2023
Approximately 20% of cancer patients experience brain metastases in the advanced stages as circulating tumor cells migrate to and colonize the brain microvasculature.
Zongjie Wang, Kangfu Chen
doaj   +1 more source

Genetic Characterization of Brain Metastases in the Era of Targeted Therapy

Frontiers in Oncology, 2017
In the current era of molecularly targeted therapies and precision medicine, choice of cancer treatment has been increasingly tailored according to the molecular or genomic characterization of the cancer the individual has.
Catherine H. Han, Catherine H. Han, Priscilla K. Brastianos   +2 more
doaj   +1 more source

Brain metastases in patients with low-grade endometrial carcinoma

Gynecologic Oncology Reports, 2018
Objective: To report characteristics of patients with low-grade endometrioid endometrial carcinoma (EC) who develop brain metastases. Methods: We retrospectively identified all patients treated at our institution for FIGO grades 1/2 EC from 1/2000–12 ...
Paulina Cybulska, Marina Stasenko, Raanan Alter, Vicky Makker, Karen A. Cadoo, Yukio Sonoda, Nadeem R. Abu-Rustum, Jennifer J. Mueller, Mario M. Leitao, Jr.   +8 more
doaj   +1 more source

Brain metastases: neuroimaging [PDF]

, 2018
Magnetic resonance imaging (MRI) is the cornerstone for evaluating patients with brain masses such as primary and metastatic tumors. Important challenges in effectively detecting and diagnosing brain metastases and in accurately characterizing their subsequent response to treatment remain.
openaire   +2 more sources

Clinical factors associated with treatment outcomes in EGFR mutant non-small cell lung cancer patients with brain metastases: a case-control observational study

BMC Cancer, 2019
Background Non-small cell lung cancer (NSCLC) patients harboring epidermal growth factor receptor (EGFR) mutations often develop brain metastases. Treatment with EGFR-tyrosine kinase inhibitors (TKIs) has shown the effectiveness; however, knowledge of ...
Yung-Hsuan Chen, Yen-Fu Chen, Chung-Yu Chen, Jin-Yuan Shih, Chong-Jen Yu   +4 more
doaj   +1 more source

Spatial and temporal heterogeneity of tumor immune microenvironment between primary tumor and brain metastases in NSCLC

BMC Cancer
Background Brain metastasis is a common outcome in non-small cell lung cancer, and despite aggressive treatment, its clinical outcome is still frustrating.
Jin-Sheng Liu, Yu-Xiang Cai, Yong-Ze He, Jian Xu, Su-Fang Tian, Zhi-Qiang Li   +5 more
doaj   +1 more source

Research Progress of Targeted Therapy in Non-small Cell Lung Cancer Brain Metastases

Chinese Journal of Lung Cancer, 2014
Lung cancer is characterized by the highest incidence of solid tumor-related brain metastases, which are reported the incidence ranged 20% to 65%. This is also one of the reasons why it can cause significant mortality.
Tao JIANG, Caicun ZHOU
doaj   +1 more source