Results 171 to 180 of about 26,410 (296)

Fast‐Track to Functional Neurons: Accessible and Minimalistic Neurogenin 2 Programming of Human iPSCs

Advanced NanoBiomed Research, EarlyView.
Fast‐track to functional human induced pluripotent stem cell (hiPSC)‐derived neurons: This colony‐initiated differentiation approach induces neurogenin 2 overexpression in dense hiPSC colonies (day 0), resulting in a structural reorganization of the colonies (day 2) before they are replated as single cells.
Jann Harberts, Malte Siegmund, Emma Wollesen, Caroline Viola, Kim Krieg, Ole Pless, Roey Elnathan, Robert Zierold, Robert H. Blick, Nicolas H. Voelcker   +9 more
wiley   +1 more source

Brain organoid technology in melanoma metastasis to the brain. [PDF]

Melanoma Manag
Rabinowitz G, Schuldt BR, Ji AL, Gulati N.   +3 more
europepmc   +1 more source

A phenotypic brain organoid atlas and biobank for neurodevelopmental disorders. [PDF]

Cell Stem Cell
Wang L, Nakamura Y, Li J, Sievert D, Liu Y, Nguyen T, Jetti PS, Thai E, Zhou RY, Weng J, Meave N, Yadavilli M, Howarth R, Camey K, Banka N, Owusu-Hammond C, Barrows C, Kingsmore SF, Zaki MS, Mukamel E, Gleeson JG.   +20 more
europepmc   +1 more source

Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment

BMEMat, EarlyView.
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan, Qiujie Fang, Cao Fei, Ziyuan Wang, Zhaowei Chen, Guojun Chen, Zhiming Xu, Shu Xu, Zhitong Chen   +8 more
wiley   +1 more source

Endocrine-disrupting effects of environmental BPS and PFOS on human brain organoid development. [PDF]

Front Endocrinol (Lausanne)
Di Credico A, Gaggi G, Bibbò S, Blenkinsop TA, Di Baldassarre A, Ghinassi B.   +5 more
europepmc   +1 more source

BRAIN ORGANOIDS - A REVIEW

International Journal of Biology, Pharmacy and Allied Sciences, 2021
openaire   +1 more source

Engineering cerebral folding in brain organoids

Neural Regeneration Research, 2022
Glen Scott, Yu Huang
openaire   +3 more sources

Precision modulation of tumor excitability: Targeting cell phenotypic heterogeneity for next‐generation cancer therapy

BMEMat, EarlyView.
This Perspective introduces tumor electrical excitability as a previously overlooked dimension of cancer biology. It proposes that tumor–neural interactions enable malignant cells to acquire neuron‐like properties and form bidirectional chemical and electrical communications with nerves.
Zonghao Liu, Xingwu Jiang, Gang Liu, Jian Chen, Kun Song, Xu Li, Siew Yee Wong, Ruicheng Shi, Yanyan Liu, Wenbo Bu   +9 more
wiley   +1 more source

All-in-one generation and multiomic profiling of human whole brain organoid on a millifluidic plate. [PDF]

Mater Today Bio
Zhao W, Wang Y, Chen T, Shen M, Wang J, Huang X, Zhu L, Yu T, Zhang Z, Yang Y, Liu M, Wang D, Huang W, Hu R, Chen P.   +14 more
europepmc   +1 more source

The ageing holobiont: crosstalk between telomere dynamics, oxidative stress and the gut microbiome

Biological Reviews, EarlyView.
ABSTRACT The gut tissue is at the frontline of early onset of ageing. It exhibits high cell turnover rates and rapid telomere shortening, which can have systemic effects on the developing or senescing organism. We conducted a literature review of studies on the crosstalk between telomere length dynamics, telomerase activity, oxidative stress, and gut ...
Michael L. Pepke, Søren B. Hansen, Morten T. Limborg   +2 more
wiley   +1 more source