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Increased reproducibility of brain organoids through controlled fluid dynamics. [PDF]
Aiello G +7 more
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The emergence of electrical activity in human brain organoids. [PDF]
Mancinelli S, Bariselli S, Lodato S.
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Nature Biotechnology, 2019
Human brain organoids are endowed with regional topography using engineered signaling centers.
Yuki Miura, Sergiu P. Pașca
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Human brain organoids are endowed with regional topography using engineered signaling centers.
Yuki Miura, Sergiu P. Pașca
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Microinstrumentation for Brain Organoids
Advanced Healthcare MaterialsAbstractBrain organoids are three‐dimensional aggregates of self‐organized differentiated stem cells that mimic the structure and function of human brain regions. Organoids bridge the gaps between conventional drug screening models such as planar mammalian cell culture, animal studies, and clinical trials.
Devan Patel +6 more
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Assembling human brain organoids
Science, 2019Three-dimensional assembloids can be used to study human development and ...
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Interdisciplinary approaches to brain organoid biology
Folia Pharmacologica Japonica, 2023Embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) have been widely used as materials for regenerative medicine and for modeling development and disease because of their pluripotency to differentiate into all cell types of the body.
Tomoki, Kodera, Fumitaka, Osakada
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Brain organoid-on-a-chip to create multiple domains in forebrain organoids
2023Abstract Brain organoids are three-dimensionally reconstructed brain tissue derived from pluripotent stem cells in vitro. 3D tissue cultures have opened new avenues for exploring development and disease modeling. However, some physiological conditions, including signaling gradients in 3D cultures, have not yet been easily achieved. Here,
Yuan-Chen Tsai +11 more
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