Results 211 to 220 of about 2,545,594 (299)

Intermittent Propofol Exposure Induces Neurodevelopmental Alterations in Human Brain Organoids. [PDF]

Cell Mol Neurobiol
Wang S, Hall C, Wang Y, Link L, Zhang Y, Schlägel A, Wunder C, Patzke C, Klein M, Mittmann T, Schäfer MKE.   +10 more
europepmc   +1 more source

Lower density of calretinin‐immunopositive neurons in the putamen of subjects with schizophrenia

Journal of Anatomy, Volume 246, Issue 4, Page 505-516, April 2025.
Recent neuroimaging and histological studies highlight the striatum as a key area involved in SCH, but the specific impairment of neuronal subtypes in subcortical structures is not fully understood. This study is the first detailed investigation of neuroanatomical changes in the putamen in SCH, specifically examining the density of calretinin ...
Paz Kelmer, Paulina Hoppa, Erzsébet Frank, Teadora Tyler, Istvan Adorjan   +4 more
wiley   +1 more source

Brain organoids as precision models for neurodegenerative diseases: from disease modeling to drug discovery. [PDF]

Front Neurosci
Zheng Y, Zhou W, Chang H, Zheng K.
europepmc   +1 more source

Reconstruction of native cellular microanatomy in a novel bioengineered full thickness human nasal mucosal construct

Journal of Anatomy, EarlyView.
Bioengineered tissue constructs are vital technologies employed in in vitro testing of both fundamental biological principles and industrial screening practices. Current approaches to modelling the nasal mucosa in vitro are not representative and are associated with limitations that impact their reliability and predictive value.
Steven Bradbury, Bethany Dickson, Nicola Curtis, David Bunton, Kirsty Goncalves, Stefan Przyborski   +5 more
wiley   +1 more source

Modelling precise responses to anti-seizure medication using brain organoids carrying SCN2A-GoF and SCN2A-LoF mutations. [PDF]

Clin Transl Med
Yang Y, Yan Y, Cai Y, Wang X, Shao Z, Ding J.   +5 more
europepmc   +1 more source

A posttranslational proteomic survey of a single anatomically preserved human 20‐week postconception brain

Journal of Anatomy, EarlyView.
A well‐preserved 20 post‐conception week human brain was obtained and finely dissected into 18 anatomically distinct regions, including the pia mater. Each region underwent in‐depth proteomic analysis, encompassing both total protein content and post‐translational modifications.
S. Bandiera, H. Bogetofte, P. Jensen, R. Hussain, S. A. Nischal, L. Rihova, G. J. Clowry, M. R. Larsen, Z. Molnár, B. C. Carlyle   +9 more
wiley   +1 more source

Focal cortical dysplasias: modeling pediatric drug-resistant epilepsy using human brain organoids. [PDF]

Front Cell Neurosci
Petralla S, Crocco E, Giustizieri M, De Palma L, Cremisi F, Cherubini E, Specchio N, Cattaneo A, Marinelli S.   +8 more
europepmc   +1 more source

The MacBrain Resource Center (MBRC) rhesus macaque postnatal brain histology datasets: Enabling new discoveries through NHP tissue and digital data Repositories

Journal of Anatomy, EarlyView.
The MacBrain Resource Center (MBRC) postnatal rhesus macaque brain histology datasets are organized into Collections that promote cost‐effective de novo research. This article provides examples from Collections 5, 6, and 7 and describes the histo‐ and immunohistochemical (IHC) processing of materials for Collection 6.
Valeria Mendoza‐Silva, Lucy Greene, Emma Burke, Cristina Canales, Julia Chocarro, Jose L. Lanciego, Khuleshwari Kurrey, Phil Barello, Aya Nusir, Nadine Kabbani, Kathleen S. Rockland, Dibyadeep Datta, Jon I. Arellano, Amy F. T. Arnsten, Yury M. Morozov, Bashir Ahmed, Zoltán Molnár, Caroline J. Zeiss, Pasko Rakic, Alvaro Duque   +19 more
wiley   +1 more source

Metformin Restores Mitochondrial Function and Neurogenesis in POLG Patient-Derived Brain Organoids. [PDF]

Adv Sci (Weinh)
Zhang Z, Yangzom T, Lu N, Deng S, Xiao X, Yang G, Liang KX.   +6 more
europepmc   +1 more source

The US Religious Public and Radical Human Enhancements

Journal for the Scientific Study of Religion, EarlyView.
ABSTRACT A radical enhancement to the human body or brain is defined as giving human capabilities that no past or present human has possessed. These are being developed by scientists and bioengineers and backed by Silicon Valley entrepreneurs. This article reports on the first study of the US religious public's views of radical enhancements using a ...
John H. Evans
wiley   +1 more source