Results 221 to 230 of about 551,653 (258)

Targeted Therapies for Brain Metastases

2019
The most common primary cancers that metastasize to the brain are lung cancer, breast cancer, and melanoma. The established management approaches for brain metastasis include stereotactic radiosurgery, fractionated radiation therapy, and surgical resection. In the past the role of medical therapies in brain metastases was limited.
Ajay, Niranjan, L Dade, Lunsford, Manmeet S, Ahluwalia   +2 more
openaire   +2 more sources

Targeted Therapy for Brain Metastases

2012
The prevention and treatment of brain metastases is an increasingly important challenge in oncology. Improved understanding of the molecular pathogenesis of a number of cancers has led to the development of highly active targeted therapies for patients with specific oncogenic events.
openaire   +2 more sources

Lipid Nanoparticles for Drug Targeting to the Brain

2012
In this chapter, the main production methods of lipid nanostructures such as solid lipid nanoparticles and nanostructured lipid carriers, and their application are described. In particular, we describe the strategies commonly used to obtain lipid nanoparticles to overcome the blood-brain barrier (BBB) for the treatment of several brain diseases.
Bondì, ML, Di Gesu', Roberto, CRAPARO, Emanuela Fabiola   +2 more
openaire   +4 more sources

Brain Targeting in MPS-IIIA.

Pediatric endocrinology reviews : PER, 2016
Mucopolysaccharidosis type IIIA (MPS-IIIA) is a childhood metabolic neuropathology caused by the inherited deficiency of the lysosomal enzyme sulfamidase and is characterized by the accumulation of undegraded glycosaminoglycans in the lysosomes of cells and tissues of affected patients.
Sorrentino, Nicolina Cristina, FRALDI, ALESSANDRO   +1 more
openaire   +2 more sources

Metabolic target for brain metastasis

Nature Reviews Drug Discovery, 2021
openaire   +2 more sources

Brain and other central nervous system tumor statistics, 2021

Ca-A Cancer Journal for Clinicians, 2021
Rebecca L. Siegel, Jill S. Barnholtz-Sloan, Carol Kruchko   +2 more
exaly  

An interdisciplinary consensus on the management of brain metastases in patients with renal cell carcinoma

Ca-A Cancer Journal for Clinicians, 2022
Marion Smits, Jeffrey Weinberg, James B Yu   +2 more
exaly  

Imaging drug targets in the brain

Nature Reviews Drug Discovery, 2022
openaire   +2 more sources

The protein corona hampers the transcytosis of transferrin-modified nanoparticles through blood–brain barrier and attenuates their targeting ability to brain tumor

Biomaterials, 2021
Wei Xiao, Yuwei Liu, Huile Gao
exaly  

Rethinking CRITID Procedure of Brain Targeting Drug Delivery: Circulation, Blood Brain Barrier Recognition, Intracellular Transport, Diseased Cell Targeting, Internalization, and Drug Release

Advanced Science, 2021
Huile Gao, Shaobo Ruan, Xinguo Jiang
exaly