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Targeted Therapies in Brain Metastases [PDF]
Current Treatment Options in Neurology, 2013 Brain metastases are a major clinical problem in patients with advanced breast cancer, lung cancer, melanoma, and renal cell carcinoma. Initial treatment for patients with brain metastases typically includes radiotherapy, either whole brain radiotherapy (WBRT), stereotactic radiosurgery (SRS), or both.
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Pharmaceutics, 2022 At present, brain diseases affect one in six people worldwide, and they include a wide range of neurological diseases from Alzheimer’s and Parkinson’s diseases to epilepsy, brain injuries, brain cancer, neuroinfections and strokes [...]
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Dual-targeting for brain-specific drug delivery: synthesis and biological evaluation
Drug Delivery, 2018 Ibuprofen is one of the most potent non-steroid anti-inflammatory drugs (NSAIDs) and plays an important role in the treatment of neurodegenerative diseases.
Qiming Yue +9 more
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Gels, 2022 (1) Background: When the body is exposed to microwave radiation, the brain is more susceptible to damage than other organs. However, few effective drugs are available for the treatment of microwave-induced brain injury (MIBI) because most drugs are ...
Yuanyuan Zhang +8 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Adult survivors of childhood acute lymphoblastic leukemia (ALL) are at risk of reduced exercise capacity, decreased physical activity levels, persistent fatigue, and neurocognitive deficits. The aim was to investigate exercise capacity and physical activity levels of adult survivors of childhood ALL and their associations with ...
Laura Jess +5 more
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Targeting the Brain to Protect the Heart
JACC: Basic to Translational Science, 2021 [Figure: see text]
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Gels, 2022 The clinical efficacy of antiretroviral therapy in NeuroAIDS is primarily limited by the low perfusion of the drug to the brain. The objective of the current investigation was to design and develop an in situ mucoadhesive gel loaded with darunavir to ...
Anroop B. Nair +10 more
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Identifying Patterns of Hospitalizations Among Childhood Cancer Survivors: A Population‐Based Study
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Childhood cancer survivors (CCSs) experience more hospitalizations than the general population. We aimed to identify distinct hospitalization patterns among Queensland CCSs and the associated characteristics. Methods Cases (aged ≤14 years) diagnosed between 1995 and 2019 while residents of Queensland were identified through the ...
Hai Pham +7 more
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Developing Brain as a Target of Toxicity
Environmental Health Perspectives, 1995 The human brain forms over an unusually long period compared to other organs. While most of the basic structure is laid down before birth, neuron proliferation and migration continue in the postnatal period. The blood-brain barrier is not fully developed until the middle of the first year of life.
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International Journal of Nanomedicine, 2019 Yueyao Jiang, Chenqi Liu, Wanchen Zhai, Ning Zhuang, Tengfei Han, Zhiying Ding School of Pharmaceutical Sciences, Jilin University, Changchun 130021, People’s Republic of ChinaCorrespondence: Zhiying DingSchool of Pharmaceutical Sciences, Jilin ...
Jiang Y +5 more
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