Results 131 to 140 of about 95,123 (282)

Development and Real‐World Evaluation of a Statewide Mainstream Model of Germline Genetic Testing for BRCA1/2 and Mismatch Repair Gene Variants (Lynch Syndrome)

Asia-Pacific Journal of Clinical Oncology, EarlyView.
This translational quality improvement study evaluated a statewide pathway for mainstream genetic testing in South Australia. Adoption of mainstream BRCA1/2 testing increased significantly, but not MMR testing. Findings highlight the need for tailored, context‐specific strategies to integrate genetic testing into routine care across diverse cancer ...
Cally A. Jennings, Kathryn Cornthwaite, Michael Osborn, Ganessan Kichenadasse, Eryn Dow   +4 more
wiley   +1 more source

Benzo[a]pyrene downregulation of BRCA1 [PDF]

, 1999
Chris Jones
openalex   +1 more source

Figure S1-S8 from Single-Cell RNA Sequencing Reveals the Cellular Origin and Evolution of Breast Cancer in <i>BRCA1</i> Mutation Carriers [PDF]

, 2023
Hu Li, Li‐Ming Su, Hainan Cheng, Chunling Mo, Tao Ouyang, Jinfeng Li, Tianfeng Wang, Zhaoqing Fan, Tie Fan, Benyao Lin, Jianguang Zhang, Yuntao Xie   +11 more
openalex   +1 more source

Cellular Stress, Inflammation and Barrier Damage in Gut Epithelial Cells Caused by Aspartame

Allergy, EarlyView.
This study shows that aspartame, at dietary‐relevant doses, induces cytotoxicity, cellular distress associated with endoplasmic reticulum stress, oxidative stress, DNA replication and repair mechanism disturbance culminating in epithelial barrier damage.
Yagiz Pat, Duygu Yazici, Can Zeyneloglu, Huseyn Babayev, Sena Ardicli, Asuncion Garci‐Sanchez, Xiangting Bu, Anja Heider, Oliva Giannelli Viscardi, Lihong Chang, Sheri Simmons, Anthony Almada, Christine Avena, Tye Jensen, Raja Dhir, Ismail Ogulur, Cezmi A. Akdis   +16 more
wiley   +1 more source

ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair [PDF]

, 2017
Justin Leung, Nodar Makharashvili, P. K. Agarwal, Li-Ya Chiu, Renaud Pourpre, Michael B. Cammarata, Joe R. Cannon, Alana Sherker, Daniel Durocher, Jennifer S. Brodbelt, Tanya T. Paull, Kyle M. Miller   +11 more
openalex   +1 more source

Selective Pectoralis Muscle Denervation Reduces Capsular Contracture in Sub‐Pectoral Breast Reconstruction. Long‐Term Retrospective Case‐ Control Study

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background Implant‐based breast reconstruction (IBBR) is the most common method of breast reconstruction globally. Although the traditional approach places implants in a retropectoral position, pre‐pectoral reconstruction has recently gained popularity due to its improved aesthetic outcomes and lower capsular contracture (CC) rates.
Marco Bernini, Federico Spolveri, Margherita Serra, Silvia Sordi, Cinzia Tommasi, Lorenzo Orzalesi, Lorenzo Tofani, Chiara Bellini, Diego De Benedetto, Jacopo Nori Cucchiari, Luca Visani, Carlotta Becherini, Viola Salvestrini, Lorenzo Livi, Icro Meattini   +14 more
wiley   +1 more source

Malignant craniopharyngiomas: Institutional experience and literature review

Brain Pathology, EarlyView.
We report the second case of malignant craniopharyngioma with BAP1 and TP53 mutations. A literature review identified 44 cases of malignant craniopharyngiomas with a median overall survival of 6 months. Eighteen (41%) occurred in patients without any history of radiation, suggesting that mechanisms other than radiation have contributed to their ...
Thomas J. Auen, Isabella W. Zhang, Weiwei Zhang, Jordan M. Burr, Matthew L. Carda, James L. Wisecarver, Nicole Shonka, Jesse L. Cox, Sahara J. Cathcart, Allison Cushman‐Vokoun, Jie Chen   +10 more
wiley   +1 more source

Supplementary Table 1 from Allelic Transcripts Dosage Effect in Morphologically Normal Ovarian Cells from Heterozygous Carriers of a <i>BRCA1</i>/<i>2</i> French Canadian Founder Mutation [PDF]

, 2023
Diala Abd-Rabbo, Christine Abaji, Guillaume B. Cardin, Abdelali Filali-Mouhim, Caroline Arous, Lise Portelance, Enrique Escobar, Sophie Cloutier, Patricia N. Tonin, Diane Provencher, Anne‐Marie Mes‐Masson, Christine M. Maugard   +11 more
openalex   +1 more source

Optic nerve sheath meningioma exhibits neural niche‐associated transcriptomic features and rare copy number variation‐linked evolution

Brain Pathology, EarlyView.
Optic nerve sheath meningiomas are typically NF2‐intact with few copy number alterations and are generally clinically indolent. Rare aggressive recurrences are associated with progressive accumulation of copy number variations, including CDKN2A/B homozygous deletion, 1q gain, and 14q loss.
Daisuke Sato, Satoru Miyawaki, Yu Sakai, Kenta Ohara, Yu Teranishi, Yudai Hirano, Motoyuki Umekawa, Takahiro Tsuchiya, Shotaro Ogawa, So Hirata, Hiroki Hongo, Hideaki Ono, Daisuke Komura, Tetsuo Ushiku, Shumpei Ishikawa, Nobuhito Saito   +15 more
wiley   +1 more source

Immunotherapie genique des cancers ovariens : etude des interactions entre p53 et les oncosuppresseurs brca1, brca2 et atm (doctorat : biologie moleculaire)

, 2000
Bénédicte Aunoble
openalex   +2 more sources