Results 51 to 60 of about 5,998 (173)
Bumetanide for autism spectrum disorder: Current evidence (eng)
Klinik Psikiyatri Dergisi, 2020 -No abstract is available since it is structured as a "Letter to the Editor".
Mazlum Çöpür, Sidar Copur
doaj +1 more source
A Case Report of a Special Type of Multiple Myeloma: Kappa Light Chain‐Only
Organ Medicine, Volume 3, Issue 2, Page 119-124, June 2026.This case illustrates the clinical course of a patient diagnosed with kappa light chain‐only multiple myeloma, a rare subtype of multiple myeloma. Of note, light chain multiple myeloma is characterized by rapid disease progression and severe target organ damage.
Yanhua Dai +8 more
wiley +1 more source
Loop diuretics have anxiolytic effects in rat models of conditioned anxiety. [PDF]
PLoS ONE, 2012 A number of antiepileptic medications that modulate GABA(A) mediated synaptic transmission are anxiolytic. The loop diuretics furosemide (Lasix) and bumetanide (Bumex) are thought to have antiepileptic properties.
Andrew D Krystal +2 more
doaj +1 more source
Association Between Furosemide and Risk of Parkinson's Disease in a Nested Case–Control Study
Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 6, June 2026.ABSTRACT A French signal detection study identified an association between sulfonamide diuretics use, particularly furosemide, and lower Parkinson's disease (PD) risk. Our aim was to confirm this association in a Finnish nationwide nested case–control study (FINPARK), primarily in an indication‐restricted case–control study of persons with heart or ...
Barkat Babar +10 more
wiley +1 more source
Frontiers in Molecular Neuroscience, 2017 Fragile X syndrome (FXS) is the most common monogenetic cause of intellectual disability and autism. The disorder is characterized by altered synaptic plasticity in the brain.
Shimriet Zeidler +3 more
doaj +1 more source
Bioethics, Volume 40, Issue 5, Page 482-490, June 2026.ABSTRACT Scientific advancements offer new possibilities for developing novel treatments for children with monogenic neurodevelopmental disorders (mNDDs), targeting the underlying effects of their condition. Although, in qualitative studies, parents of children with mNDDs have predominantly positive attitudes towards the development of novel treatments,
Sietske A. L. van Till +4 more
wiley +1 more source
Potassium channel and NKCC cotransporter involvement in ocular refractive control mechanisms. [PDF]
PLoS ONE, 2008 Myopia affects well over 30% of adult humans globally. However, the underlying physiological mechanism is little understood. This study tested the hypothesis that ocular growth and refractive compensation to optical defocus can be controlled by ...
Sheila G Crewther +2 more
doaj +1 more source
Dexamethasone‐Mediated Regulation of CYP3A4 and UGTs in Human Hepatoma HuH‐7 Cells
Fundamental &Clinical Pharmacology, Volume 40, Issue 3, May 2026.ABSTRACT Background The application of human hepatic cell lines to early drug discovery and development instead of human primary hepatocytes (HPHs) has been limited because of the low level of drug‐metabolizing enzymes (DMEs). Objective The study aimed to evaluate the effects of dexamethasone (DEX) treatment on DME expression, activities, and ...
Hana Yu +4 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 891-904, April 2026.Limited evidence exists synthesizing the risk of acute kidney injury (AKI) associated with the concomitant administration of multiple nephrotoxic drugs, and even less examining the concept of nephrotoxic burden. The objective of this scoping review was to (1) identify definitions of nephrotoxic burden; (2) methods used to quantify (use of calculations)
Wafa Alatawi +6 more
wiley +1 more source
Drug Testing and Analysis, Volume 18, Issue 4, Page 458-482, April 2026.New insights into drug metabolism, distribution, elimination, and detection assays for drugs and methods of sports doping published between 2024 and 2025 are critically reviewed and evaluated in context with the Prohibited List 2025 as established by the World Anti‐Doping Agency.
Mario Thevis, Tiia Kuuranne, Hans Geyer
wiley +1 more source