Results 61 to 70 of about 8,274 (202)

Effect of Co-administration of Bumetanide and Phenobarbital on Seizure Attacks in Temporal Lobe Epilepsy

open access: yesBasic and Clinical Neuroscience, 2018
Introduction: The resistance of temporal lobe epilepsy to classic drugs is thought to be due to disruption in the excitation/inhibition of this pathway.
Reza Rahmanzadeh   +8 more
doaj  

Association Between the Red Blood Cell Distribution Width‐to‐Albumin Ratio, Nursing Notes, and the Length of Hospital Stay in Iron Deficiency Anaemia Complicated With Congestive Heart Failure Patients

open access: yesNursing Open, Volume 13, Issue 7, July 2026.
ABSTRACT Aims To evaluate the influence of the red blood cell distribution width‐to‐albumin ratio (RAR) and sentiment scores from nursing notes on the length of hospital stay (LOS) and mortality risk among iron deficiency anaemia (IDA) patients with congestive heart failure (CHF). Design A retrospective study.
Xiao‐fang Fang   +5 more
wiley   +1 more source

Emerging Medications in Facial Nerve Recovery: A Systematic Review and Meta‐Analysis

open access: yesOTO Open, Volume 10, Issue 3, July-September 2026.
Abstract Objective To systematically review the literature for medical therapies that promote facial nerve regeneration and recovery. Data Sources PubMed/Medline, Embase, and SCOPUS databases were searched for English‐language studies published from inception through May 2025.
Kimberly Chan   +5 more
wiley   +1 more source

Combination Therapy in Fragile X Syndrome; Possibilities and Pitfalls Illustrated by Targeting the mGluR5 and GABA Pathway Simultaneously

open access: yesFrontiers in Molecular Neuroscience, 2017
Fragile X syndrome (FXS) is the most common monogenetic cause of intellectual disability and autism. The disorder is characterized by altered synaptic plasticity in the brain.
Shimriet Zeidler   +3 more
doaj   +1 more source

Potassium channel and NKCC cotransporter involvement in ocular refractive control mechanisms. [PDF]

open access: yesPLoS ONE, 2008
Myopia affects well over 30% of adult humans globally. However, the underlying physiological mechanism is little understood. This study tested the hypothesis that ocular growth and refractive compensation to optical defocus can be controlled by ...
Sheila G Crewther   +2 more
doaj   +1 more source

Learning Dynamics in Biophysical Spiking Network Models Are Shaped by KCC2/NKCC1 Cotransporter Stoichiometry

open access: yesEuropean Journal of Neuroscience, Volume 64, Issue 1, July 2026.
Neuronal chloride homeostasis, governed by KCC2 and NKCC1 cotransporters, constrains convergence to learning in biophysical spiking neural networks. Systematic exploration of transporter activity shows that successful learning emerges only within a restricted parameter regime, whose boundaries and convergence properties critically depend on NKCC1 ...
Mohamed Ahmed   +3 more
wiley   +1 more source

Dynamic Functional Network Connectivity Analysis in Autism Spectrum Disorder: An EEG Study

open access: yesIEEE Access
Convergent evidence has suggested a significant effect of bumetanide exposure on brain connectivity in patients with autism spectrum disorder (ASD), yet the characteristics of favorable treatment outcome remains largely unknown. In this work, we aimed to
Seyedeh Negin Seyed Fakhari   +3 more
doaj   +1 more source

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1420-1428, June 2026.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Embryonic cerebrospinal fluid pressure in fetal mice in utero: External factors pressurize the intraventricular space

open access: yesDevelopmental Dynamics, Volume 255, Issue 6, Page 533-547, June 2026.
Abstract Background Previous experiments inducing leakage of embryonic cerebrospinal fluid (CSF) suggest the necessity of intraventricular CSF pressure (PCSF) for brain morphogenesis. Nevertheless, how embryonic PCSF occurs is unclear, especially in utero. Results Using a Landis water manometer, we measured PCSF in fetal mice isolated from the amniotic
Koichiro Tsujikawa   +2 more
wiley   +1 more source

A Case Report of a Special Type of Multiple Myeloma: Kappa Light Chain‐Only

open access: yesOrgan Medicine, Volume 3, Issue 2, Page 119-124, June 2026.
This case illustrates the clinical course of a patient diagnosed with kappa light chain‐only multiple myeloma, a rare subtype of multiple myeloma. Of note, light chain multiple myeloma is characterized by rapid disease progression and severe target organ damage.
Yanhua Dai   +8 more
wiley   +1 more source

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