Results 61 to 70 of about 8,546 (246)
Determinants of bumetanide response in the dog: Effect of probenecid [PDF]
, 1983 The pharmacokinetics and pharmacodynamics of intravenous bumetanide (0.250 mg/kg), alone (treatment I) and after probenecid pretreatment (treatment II), were studied in four mongrel dogs.
Lau, Henry S. H., Smith, David E.
core +1 more source
Frontiers in Physiology, 2020 Introduction: Na+-K+-2Cl− cotransporter isoform 1 (NKCC1) is important in regulating intracellular K+ and Cl− homeostasis and cell volume. In this study, we investigated a role of NKCC1 in regulating glioma K+ influx and proliferation in response to ...
Lanxin Luo +14 more
doaj +1 more source
Developmental Dynamics, Volume 255, Issue 6, Page 533-547, June 2026.Abstract Background Previous experiments inducing leakage of embryonic cerebrospinal fluid (CSF) suggest the necessity of intraventricular CSF pressure (PCSF) for brain morphogenesis. Nevertheless, how embryonic PCSF occurs is unclear, especially in utero. Results Using a Landis water manometer, we measured PCSF in fetal mice isolated from the amniotic
Koichiro Tsujikawa +2 more
wiley +1 more source
Asthmatic Airway Vagal Hypertonia Involves Chloride Dyshomeostasis of Preganglionic Neurons in Rats
Frontiers in Neuroscience, 2020 Airway vagal hypertonia is closely related to the severity of asthma; however, the mechanisms of its genesis are unclear. This study aims to prove that asthmatic airway vagal hypertonia involves neuronal Cl– dyshomeostasis.
Ding He +8 more
doaj +1 more source
A Case Report of a Special Type of Multiple Myeloma: Kappa Light Chain‐Only
Organ Medicine, Volume 3, Issue 2, Page 119-124, June 2026.This case illustrates the clinical course of a patient diagnosed with kappa light chain‐only multiple myeloma, a rare subtype of multiple myeloma. Of note, light chain multiple myeloma is characterized by rapid disease progression and severe target organ damage.
Yanhua Dai +8 more
wiley +1 more source
Bumetanide Prevents Brain Trauma-Induced Depressive-Like Behavior
Frontiers in Molecular Neuroscience, 2019 Brain trauma triggers a cascade of deleterious events leading to enhanced incidence of drug resistant epilepsies, depression, and cognitive dysfunctions.
Emmanuelle Goubert +10 more
doaj +1 more source
Association Between Furosemide and Risk of Parkinson's Disease in a Nested Case–Control Study
Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 6, June 2026.ABSTRACT A French signal detection study identified an association between sulfonamide diuretics use, particularly furosemide, and lower Parkinson's disease (PD) risk. Our aim was to confirm this association in a Finnish nationwide nested case–control study (FINPARK), primarily in an indication‐restricted case–control study of persons with heart or ...
Barkat Babar +10 more
wiley +1 more source
Effects of bumetanide on direction selectivity.
, 2013 Comparison of the direction selectivity index DSI (ordinate) during ON and OFF stimulation before (grey columns) and after (white columns) intravitreous application of bumetanide averaged (mean and standard deviation) over all units recorded.
Klaus-Peter Hoffmann (252667) +3 more
core +1 more source
Bioethics, Volume 40, Issue 5, Page 482-490, June 2026.ABSTRACT Scientific advancements offer new possibilities for developing novel treatments for children with monogenic neurodevelopmental disorders (mNDDs), targeting the underlying effects of their condition. Although, in qualitative studies, parents of children with mNDDs have predominantly positive attitudes towards the development of novel treatments,
Sietske A. L. van Till +4 more
wiley +1 more source
Paradoxical Benzodiazepine Response: A Rationale for Bumetanide in Neurodevelopmental Disorders?
, 2015 The diuretic agent bumetanide has recently been put forward as a novel, promising treatment of behavioral symptoms in autism spectrum disorder (ASD) and related conditions.
Goriounova, N.A.; id_orcid +14 more
core +1 more source