Results 71 to 80 of about 8,546 (246)
Medicine, 2020 Rationale: Autism spectrum disorder (ASD) is a common neurodevelopmental disorder caused by complex interactions between genetic and environmental factors.
Jun-yan Feng +4 more
semanticscholar +1 more source
A Hidden Culprit: Aldosteronoma as a Rare Cause of Refractory Hypertension in Autosomal‐Dominant Polycystic Kidney Disease [PDF]
Clin Case RepABSTRACT Hypertension is common in autosomal‐dominant polycystic kidney disease (ADPKD) but may occasionally reflect a secondary etiology. We report a 71‐year‐old man with ADPKD and end‐stage renal disease who developed persistent, refractory hypertension following renal transplantation despite multidrug therapy and bilateral native nephrectomy ...
Wainstein M +7 more
europepmc +2 more sources
Dexamethasone‐Mediated Regulation of CYP3A4 and UGTs in Human Hepatoma HuH‐7 Cells
Fundamental &Clinical Pharmacology, Volume 40, Issue 3, May 2026.ABSTRACT Background The application of human hepatic cell lines to early drug discovery and development instead of human primary hepatocytes (HPHs) has been limited because of the low level of drug‐metabolizing enzymes (DMEs). Objective The study aimed to evaluate the effects of dexamethasone (DEX) treatment on DME expression, activities, and ...
Hana Yu +4 more
wiley +1 more source
Binding of bumetanide to microsomes from optic ganglia of the squid, Loligo pealei
, 1990 Saturable high-affinity binding of [3H] bumetanide [dissociation constant (KD) = 80 nM] was measured in microsomal membranes prepared from squid optic ganglia.
J. M. Russell +2 more
core +1 more source
Structure of Sodium Bumetanide Trihydrate
, 1995 The structure of sodium 3-(aminosulfonyl)-5-(butylamino)- 4-phenoxybenzoate trihydrate (sodium bumetanide trihydrate), Na +.C 17HI9N205S-.3H20, consists of a layer of sodium ions and water molecules between two layers of bumetanide molecules ...
L. ZACCARO +4 more
core +1 more source
Clinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 891-904, April 2026.Limited evidence exists synthesizing the risk of acute kidney injury (AKI) associated with the concomitant administration of multiple nephrotoxic drugs, and even less examining the concept of nephrotoxic burden. The objective of this scoping review was to (1) identify definitions of nephrotoxic burden; (2) methods used to quantify (use of calculations)
Wafa Alatawi +6 more
wiley +1 more source
Novel bumetanide-sensitive K+ transport in preimplantation mouse conceptuses
, 1992 Ouabain-resistant K+ transport activity was characterized primarily by measuring Rb+ uptake because 86Rb+ has a more convenient half-life than 42K+. Ouabain-resistant 86Rb+ uptake by mouse two-cell conceptuses and blastocysts was slowed by the K(+)-Na(+)-
A. L. Campione, L. J. Van Winkle
core +1 more source
Drug Testing and Analysis, Volume 18, Issue 4, Page 458-482, April 2026.New insights into drug metabolism, distribution, elimination, and detection assays for drugs and methods of sports doping published between 2024 and 2025 are critically reviewed and evaluated in context with the Prohibited List 2025 as established by the World Anti‐Doping Agency.
Mario Thevis, Tiia Kuuranne, Hans Geyer
wiley +1 more source
Dynamic Functional Network Connectivity Analysis in Autism Spectrum Disorder: An EEG Study
IEEE AccessConvergent evidence has suggested a significant effect of bumetanide exposure on brain connectivity in patients with autism spectrum disorder (ASD), yet the characteristics of favorable treatment outcome remains largely unknown. In this work, we aimed to
Seyedeh Negin Seyed Fakhari +3 more
doaj +1 more source
FORMULATION AND DEVELOPMENT OF ORAL DISSOLVING FILMS OF BUMETANIDE
, 2016 Objective: Formulation and Development of oral dissolving Films of Bumetanide. Materials and methods: BUMETANIDE, HPMC E-50, HPMC E-5, HPMC E-3, PE, 4000 (Flakes) and Aspartame. Citric Acid could be formulated with low viscosity film formers viz.
Dr.A.Yasodha
core +1 more source