Results 61 to 70 of about 6,633 (239)

The Native Orthobunyavirus Ribonucleoprotein Possesses a Helical Architecture

open access: yesmBio, 2022
The Bunyavirales order is the largest group of negative-sense RNA viruses, containing many lethal human pathogens for which approved anti-infective measures are not available.
Francis R. Hopkins   +7 more
doaj   +1 more source

Distribution of tick-borne diseases in China [PDF]

open access: yes, 2013
As an important contributor to vector-borne diseases in China, in recent years, tick-borne diseases have attracted much attention because of their increasing incidence and consequent significant harm to livestock and human health.
Hong-Juan Peng   +4 more
core   +1 more source

Virus-host interactions during tick-borne bunyavirus infection

open access: yesCurrent Opinion in Virology, 2022
The Bunyavirales order is the largest grouping of RNA viruses, comprising emerging and re-emerging human, plant and animal pathogens. Bunyaviruses have a global distribution and many members of the order are transmitted by arthropods. They have evolved a plethora of mechanisms to manipulate the regulatory processes of the infected cell to facilitate ...
Mazigh Fares, Benjamin Brennan
openaire   +2 more sources

The fundamental role of endothelial cells in hantavirus pathogenesis

open access: yesFrontiers in Microbiology, 2014
Hantavirus, a genus of rodent- and insectivore-borne viruses in the family Bunyaviridae, is a group of emerging zoonotic pathogens. Hantaviruses cause hemorrhagic fever with renal syndrome (HFRS) and hantavirus cardiopulmonary syndrome (HCPS) in man ...
Jussi eHepojoki   +2 more
doaj   +1 more source

Investigations on Vector-Borne and Aerosol Transmission Potential of Kaeng Khoi Virus in Cave-Dwelling Wrinkle-Lipped Free-Tailed Bats (Chaerephon plicatus) in Thailand

open access: yesMicroorganisms, 2021
Kaeng Khoi virus (KKV; Order: Bunyavirales, Family: Peribunyaviridae, Genus: Orthobunyavirus), is an endemic viral infection of the wrinkle-lipped free-tailed bat (Chaerephon plicatus; also known as Tadarida plicata plicata). Viral isolates from bat bugs
William A. Neill, Rebekah C. Kading
doaj   +1 more source

Metagenomic-based Surveillance of Pacific Coast tick Dermacentor occidentalis Identifies Two Novel Bunyaviruses and an Emerging Human Ricksettsial Pathogen. [PDF]

open access: yes, 2017
An increasing number of emerging tick-borne diseases has been reported in the United States since the 1970s. Using metagenomic next generation sequencing, we detected nucleic acid sequences from 2 novel viruses in the family Bunyaviridae and an emerging ...
Bouquet, Jerome   +5 more
core   +2 more sources

RNAi Regulator C3PO Promotes Arbovirus Infection in Insect Vectors

open access: yesAdvanced Science, Volume 13, Issue 4, 19 January 2026.
RNA interference (RNAi) is vital for eukaryotes to defend against virus infection. The C3PO complex takes part in RNAi but its role in regulating viral infection remains unclear. This work finds that insect C3PO facilitates arbovirus replication by degrading precursors of miRNAs, especially miR‐971‐3p.
Yan Xiao   +7 more
wiley   +1 more source

The lipopeptide Pam3CSK4 inhibits Rift Valley fever virus infection and protects from encephalitis.

open access: yesPLoS Pathogens
Rift Valley fever virus (RVFV) is an encephalitic bunyavirus that can infect neurons in the brain. There are no approved therapeutics that can protect from RVFV encephalitis.
Trevor Griesman   +11 more
doaj   +1 more source

Recent Advances in Bunyavirus Reverse Genetics Research: Systems Development, Applications, and Future Perspectives

open access: yesFrontiers in Microbiology, 2021
Bunyaviruses are members of the Bunyavirales order, which is the largest group of RNA viruses, comprising 12 families, including a large group of emerging and re-emerging viruses.
Fuli Ren   +14 more
doaj   +1 more source

Strategic Preparedness of Broad‐Spectrum Antivirals for Rapid Response Towards Next Pandemics

open access: yesSmall Science, Volume 6, Issue 1, January 2026.
Nanoengineered broad‐spectrum antivirals (BSAs) represent a transformative approach to pandemic preparedness. Unlike virus‐specific drugs requiring separate development, BSAs act across multiple viral families through nanoengineering strategies that enhance solubility, bioavailability, and host‐targeted activity.
Sanoj Rejinold N   +2 more
wiley   +1 more source

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