Results 11 to 20 of about 106,461 (152)
Co(III) Intermediates in Cobalt-Catalyzed, Bidentate Chelation Assisted C(sp2)-H Functionalizations
Inorganics, 2023 The C-H bond activation and functionalization is a powerful tool that provides efficient access to various organic molecules. The cobalt-catalyzed oxidative C-H bond activation and functionalization has earned enormous interest over the past two decades.
Aleksandrs Cizikovs, Liene Grigorjeva
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Frontiers in Chemistry, 2021 Selectively activating the distal inactive C-H bond for functionalization is one of the on-going challenge in organic synthetic chemistry. In recent years, benefiting from the development of selective synthesis methods, novel methodologies not only make ...
Huang Junrong +11 more
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Transition Metal-Catalyzed Remote C–H Bond Functionalization of Cyclic Amines
SynOpen, 2022 C–H bond functionalization is one of the most effective strategies for the rapid synthesis of cyclic amines containing substituents in the ring, which are core structures of many bioactive molecules. It is, however, much more challenging to perform this
Weijie Chen, Xiaoyu Yang, Xi Cao
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Tuning Benzylic C−H Functionalization of (Thio)xanthenes with Electrochemistry
Molecules, 2023 Here, we report a tunable electrochemical benzylic C−H functionalization of (thio)xanthenes with terminal alkynes and nitriles in the absence of any catalyst or external chemical oxidant.
Changji Wang +4 more
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Strategies to transform remote C(sp3)-H bonds of amino acid derivatives
Tetrahedron Chem, 2022 Amino acids and peptides play an important role in nature as well as in the pharmaceutical industry. Therefore, transformation of amino acids and peptides into their unnatural derivatives via step and atom economical ways is highly demanding. Although, a
Supreeta Sen +2 more
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Coumarins Synthesis and Transformation via C–H Bond Activation—A Review
Inorganics, 2022 For several decades, coumarins have attracted considerable attention due to the fact of their application in diverse fields such as medical science and biomedical research as well as several industrial branches.
Katarzyna Szwaczko
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Triazole-Directed Pd-Catalyzed C(sp2)–H Oxygenation of Arenes and Alkenes [PDF]
, 2016 Selective Pd-catalyzed C(sp2)–H oxygenation of 4-substituted 1,2,3-triazoles is described. Unlike previous metal-catalyzed C–H functionalization events, which preferentially occur at the activated heterocyclic C–H bond, the regioselective oxygenation of ...
Aizpurua Iparraguirre, Jesús María +2 more
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A Simple Access to γ‐ and ε‐Keto Arenes via Enzymatic Divergent C─H Bond Oxyfunctionalization
Advanced Science, 2023 Performing divergent C─H bond functionalization on molecules with multiple reaction sites is a significant challenge in organic chemistry. Biocatalytic oxyfunctionalization reactions of these compounds to the corresponding ketones/aldehydes are typically
Huanhuan Li +6 more
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Enzymatic functionalization of carbon-hydrogen bonds [PDF]
, 2011 The development of new catalytic methods to functionalize carbon–hydrogen (C–H) bonds continues to progress at a rapid pace due to the significant economic and environmental benefits of these transformations over traditional synthetic methods.
Arnold, Frances H. +2 more
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Palladium-Catalyzed Site-Selective Fluorination of Unactivated C(sp3)−H Bonds [PDF]
, 2015 The transition-metal-catalyzed direct C–H bond fluorination is an attractive synthetic tool toward the preparation of organofluorines. While many methods exist for the direct sp3 C–H functionalization, site-selective fluorination of unactivated sp3 ...
Ge, Haibo +3 more
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