Results 21 to 30 of about 45,483 (213)

Cp∗Rh/Ag catalyzed C–H activation/cyclization sequences of NH-sulfoximines to fused aza-polyheterocycles under gentle conditions

Green Synthesis and Catalysis, 2023
Disclosed herein is a novel Rh/Ag co-catalyzed SNH directed C–H activation and C–H/N–H bond functionalization protocol of free NH-sulfoximines with hypervalent iodonium ylides.
Jiapian Huang, Fei Liu, Feihua Du, Linghui Zeng, Zhiyuan Chen   +4 more
doaj   +1 more source

Robust molecular trends in Pd-catalyzed C(sp2/sp3)-H activation reactions – A review

Results in Chemistry, 2021
Direct functionalization of inert C–H bonds into various C-X (X = C, N, O, S) functionalities is one of the frontier research topics and regularly gaining popularities among the communities of scientists by providing opportunities for direct synthesis of
Pravati Panda, Kaushik Pal, Subhendu Chakroborty   +2 more
doaj   +1 more source

Recent Advances in the Nickel-Catalyzed Alkylation of C-H Bonds

Molecules
Functionalization of C-H bonds has emerged as a powerful strategy for converting inert, nonfunctional C-H bonds into their reactive counterparts.
Franc Požgan, Uroš Grošelj, Jurij Svete, Bogdan Štefane, Hamad H. Al Mamari   +4 more
doaj   +1 more source

Selective Dealkenylative Functionalization of Styrenes via C-C Bond Cleavage

Research, 2020
As a readily available feedstock, styrene with about 25 million tons of global annual production serves as an important building block and organic synthon for the synthesis of fine chemicals, polystyrene plastics, and elastomers.
Jianzhong Liu, Jun Pan, Xiao Luo, Xu Qiu, Cheng Zhang, Ning Jiao   +5 more
doaj   +1 more source

Recent Developments in Transition-Metal Catalyzed Direct C–H Alkenylation, Alkylation, and Alkynylation of Azoles

Molecules, 2020
The transition metal-catalyzed C–H bond functionalization of azoles has emerged as one of the most important strategies to decorate these biologically important scaffolds. Despite significant progress in the C–H functionalization of various heteroarenes,
Su Chen, Prabhat Ranjan, Leonid G. Voskressensky, Erik V. Van der Eycken, Upendra K. Sharma   +4 more
doaj   +1 more source

Recent advances in direct α-C(sp3)-H bond functionalization of thioethers

Green Synthesis and Catalysis, 2022
Thioether skeletons are widely present in drugs, natural products, functional materials, and life science. In the past decade, the selective C–H functionalization of thioethers has been extensively studied to construct novel thioether derivatives.
Long Tang, Qingyue Hu, Ke Yang, Mazen Elsaid, Chong Liu, Haibo Ge   +5 more
doaj   +1 more source

Psychosocial Functioning After Pediatric Bone Sarcoma: Generic and Survivor‐Specific Outcomes in Adolescent and Young Adult Patients

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric bone sarcoma patients and survivors may experience psychosocial challenges related to childhood cancer after their intensive, body‐altering treatment. This cross‐sectional study aimed to evaluate generic and survivor‐specific psychosocial outcomes in a national cohort of pediatric bone sarcoma patients and survivors, and ...
Hinke van der Hoek, Heleen Maurice‐Stam, Laura R. Beek, Jennifer van Dijk, Marjolein E. M. Langemeijer, Relinde W. Slooff‐Lentink, Alied M. van der Aa‐van Delden, Anne Westerweel, Marloes van Gorp, Hendrik W. B. Schreuder, Lianne M. Haveman, W. Peter Bekkering, Leonie G. Tigelaar, Johannes H. M. Merks, Martha A. Grootenhuis   +14 more
wiley   +1 more source

Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean, Lara V. Graham, Christina Putnam, Rosa Gomes Alves Martins, Daniel T. Harding, Tim J. Underwood, Zoë S. Walters, Matthew D. Blunt   +7 more
wiley   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source