Results 21 to 30 of about 52,780 (297)

Chiral N‐Heterocyclic Carbene Ligands Enable Asymmetric C−H Bond Functionalization

, 2019
International audienceThe asymmetric functionalization of C‐H bond is a particularly valuable approach for the production of enantioenriched chiral organic compounds.
Jompol Thongpaen, Romane Manguin, Olivier Baslé   +2 more
openalex   +3 more sources

Strategies to transform remote C(sp3)-H bonds of amino acid derivatives

Tetrahedron Chem, 2022
Amino acids and peptides play an important role in nature as well as in the pharmaceutical industry. Therefore, transformation of amino acids and peptides into their unnatural derivatives via step and atom economical ways is highly demanding. Although, a
Supreeta Sen, Jayabrata Das, Debabrata Maiti   +2 more
doaj   +1 more source

C–H Functionalization via Iodine-mediated Electrocatalysis and C–N Bond Formation

, 2022
The access of heterocyclic compounds via direct amination of C-H bonds are of vital interest because of their role in pharmaceutical and natural products. The combination of molecular iodine and electricity activates benzylic C-H bond and facilitates the
Guilherme. M., Martins, Nisar, Ahmed
core   +1 more source

Ligand control of hydrocarbon C-H bond functionalization by uranyl photocatalysts

, 2023
The aqueous uranyl dication has long been known to facilitate the UV light-induced decomposition of aqueous VOCs (volatile organic compounds), via the long-lived highly efficient, uranyl excited state.
Polly, Arnold, Sean, Woodall, Adam, Woodward, Xiaobin, Zhang, Georg, Schreckenbach, Mark, Sarsfield, Louise, Natrajan, James, Purkis, Ryte, Rutkauskaite   +8 more
core   +1 more source

Coumarins Synthesis and Transformation via C–H Bond Activation—A Review

Inorganics, 2022
For several decades, coumarins have attracted considerable attention due to the fact of their application in diverse fields such as medical science and biomedical research as well as several industrial branches.
Katarzyna Szwaczko
doaj   +1 more source

A Simple Access to γ‐ and ε‐Keto Arenes via Enzymatic Divergent C─H Bond Oxyfunctionalization

Advanced Science, 2023
Performing divergent C─H bond functionalization on molecules with multiple reaction sites is a significant challenge in organic chemistry. Biocatalytic oxyfunctionalization reactions of these compounds to the corresponding ketones/aldehydes are typically
Huanhuan Li, Yalan Zhang, Yawen Huang, Peigao Duan, Ran Ge, Xiaofeng Han, Wuyuan Zhang   +6 more
doaj   +1 more source

Steric, Electronic and Conformational Synergistic Effects in the Au(I)-catalyzed alpha-C-H Bond Functionalization of Tertiary Amines

, 2022
Direct C-H bond functionalization is a useful strategy for the straightforward formation of C-C and C-Heteroatom bonds. In the present work, a unique approach for the challenging electrophilic Au-catalyzed alpha-C-H bond functionalization of tertiary ...
David F. , León Rayo, Wenbin, Wu, Benjamin N., Bhawal, Ali, Mansour, Fabien, Gagosz   +4 more
core   +1 more source

Transition Metal Catalyzed C−H bond Activation as a Sustainable Strategy for The Synthesis of Fluorinated Molecules: An overview

, 2023
International audienceThe last decade has witnessed the emergence of innovative synthetic tools for the synthesis of fluorinated molecules. Among these approaches, the transition metal catalyzed functionalization of various scaffolds with a panel of ...
Besset, Tatiana, Doche, Floriane, Monsigny, Louis   +2 more
core   +1 more source

Unconventional mechanism and selectivity of the Pd-catalyzed C–H bond lactonization in aromatic carboxylic acid

Nature Communications, 2022
Methods to functionalize inert C–H bonds are a critical focus of synthetic organic chemistry. In this work the authors use computations and experiments to uncover the mechanisms of palladium-catalysed C–H lactonizations in aromatic carboxylic acids, and ...
Li-Ping Xu, Shaoqun Qian, Zhe Zhuang, Jin-Quan Yu, Djamaladdin G. Musaev   +4 more
doaj   +1 more source

Ligand Accelerated Hydrogen Isotope Exchange: Switching C-H Activation from Functionalization Towards C-D Bond Formation

, 2023
Hydrogen isotope exchange (HIE) has emerged as a unique strategy for labelling, affording plenty of deuterated chemicals with varieties in patterns.
Jianfei, Bai, Bencan, Tang, Dawei, Xu, Jiakai, Lu, Zhi-Jiang, Jiang, Zhanghua, Gao, Jia, Chen   +6 more
core   +1 more source