Results 41 to 50 of about 27,304,717 (282)
Distal Functionalization via Transition Metal Catalysis
Chemistry Proceedings, 2022 The ubiquitous presence of sp3 C−H bonds in natural feedstock makes them inexpensive, easily accessible, and attractive synthons for the preparation of common and/or complex molecular frameworks in biologically active natural products, pharmaceutics ...
Haibo Ge
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, 2023 International audienceThe last decade has witnessed the emergence of innovative synthetic tools for the synthesis of fluorinated molecules. Among these approaches, the transition metal catalyzed functionalization of various scaffolds with a panel of ...
Besset, Tatiana +2 more
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Organophotoredox-Catalyzed Direct C-H Functionalization of “Drug Prejudice” at Room Temperature [PDF]
, 2020 Organophotocatalytic C─H bond functionalization has attracted lot of attention in the past several years due to the possibility of catalysing reactions in a metal-free environment.
Narendra, Chaubey +2 more
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Synthesis of Phthalides and α,β-butenolides by Transition Metal-Catalyzed Activation of C—H Bonds
Molecules, 2019 Phthalides and α,β-butenolides are two related classes of oxygenated heterocycles with a wide range of biological activities. An innovative strategy to prepare these compounds is based on C—H bond functionalization reactions, in which two
Andrea Renzetti, Kozo Fukumoto
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Green Synthesis and Catalysis, 2023 Disclosed herein is a novel Rh/Ag co-catalyzed SNH directed C–H activation and C–H/N–H bond functionalization protocol of free NH-sulfoximines with hypervalent iodonium ylides.
Jiapian Huang +4 more
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Pushing the boundaries of C–H bond functionalization chemistry using flow technology
Journal of Flow Chemistry, 2020 C–H functionalization chemistry is one of the most vibrant research areas within synthetic organic chemistry. While most researchers focus on the development of small-scale batch-type transformations, more recently such transformations have been carried ...
Sebastian Govaerts, A. Nyuchev, T. Noel
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Rhodium catalyzed chelation-assisted C-H bond functionalization reactions
Accounts of Chemical Research, 2011 Conspectus Over the last several decades, researchers have achieved remarkable progress in the field of organometallic chemistry. The development of metal-catalyzed cross-coupling reactions represents a paradigm shift in chemical synthesis, and today ...
D. A. Colby +3 more
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Radical‐Promoted Distal C‐H Functionalization of C(sp3) Centers with Fluorinated Moieties
, 2020 International audienceDue to their unique properties, fluorinated scaffolds are pivotal compounds in pharmaceuticals, agrochemicals and materials science.
Tatiana Besset +5 more
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A general strategy for C(sp3)–H functionalization with nucleophiles using methyl radical as a hydrogen atom abstractor [PDF]
, 2021 Photoredox catalysis has provided many approaches to C(sp3)-H functionalization that enable selective oxidation and C(sp3)-C bond formation via the intermediacy of a carbon-centered radical. While highly enabling, functionalization of the carbon-centered
Isabelle, Leibler +5 more
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Controlling Site Selectivity in Palladium-Catalyzed C–H Bond Functionalization
Accounts of Chemical Research, 2012 Conspectus Effective methodology to functionalize C–H bonds requires overcoming the key challenge of differentiating among the multitude of C–H bonds that are present in complex organic molecules.
S. Neufeldt, M. Sanford
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