Recent advances in direct α-C(sp3)-H bond functionalization of thioethers
Green Synthesis and Catalysis, 2022 Thioether skeletons are widely present in drugs, natural products, functional materials, and life science. In the past decade, the selective C–H functionalization of thioethers has been extensively studied to construct novel thioether derivatives.
Long Tang +5 more
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Synthesis of nitroxyl radical by direct nucleophilic functionalization of a C-H bond in the azadiene systems [PDF]
, 2012 Cyclic dinitrones underwent nucleophilic substitution of the hydrogen atom in the reaction with a paramagnetic carbanion, the lithium derivative of 4,4,5,5-tetramethyl-4,5-dihydro-1H-imidazol-1-oxyl 3-oxide, to give polyfunctional nitronyl nitroxyls ...
Bogomyakov, A. S. +8 more
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Synthesis of Symmetrical and Unsymmetrical 1,3-Diheteroarylbenzenes Through Palladium-Catalyzed Direct Arylation of Benzene-1,3-disulfonyl Dichloride and 3-Bromobenzenesulfonyl Chlorides [PDF]
, 2015 International audienceThe palladium-catalyzed synthesis of unsymmetrical 1,3-diheteroarylbenzenes was investigated. The first synthetic pathway relies on the desymmetrization of benzene-1,3-disulfonyl dichloride through two successive palladium-catalyzed
Derridj, Fazia +4 more
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C–H bond functionalizations with palladium(II): intramolecular oxidative annulations of arenes [PDF]
, 2008 Oxidative annulations for the synthesis of carbocycles were developed using a catalytic palladium(II) system. Indoles with pendant olefin tethers were oxidatively cyclized to form annulated products. Electron-rich aromatic systems were also investigated,
Ferreira, Eric M. +2 more
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Intermolecular Radical C–H Bond Activation: A Powerful Tool for Late Stage Functionalization
CHIMIA, 2020 The synthesis of complex molecules via radical reactions involving carbon–carbon and carbon–heteroatom bonds has become a very successful approach. Radical chemistry has long been dominated by the use of tin-based reagents.
Fabrice Dénès
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Kinetic study of H-terminated silicon nanowires oxidation in very first stages [PDF]
, 2013 Oxidation of silicon nanowires (Si NWs) is an undesirable phenomenon that has a detrimental effect on their electronic properties. To prevent oxidation of Si NWs, a deeper understanding of the oxidation reaction kinetics is necessary. In the current work,
Bashouti, Muhammad Y. +3 more
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Intramolecular Arene C−H to C−P Functionalization Mediated by Nickel(II) and Palladium(II) [PDF]
, 2013 A tris(phosphine) ligand with a triarylbenzene backbone was employed to support mono-nickel(II) and -palladium(II) complexes. Two phosphine arms coordinated to the metal center, while the third phosphine was found to form a C–P bond with dearomatization ...
Agapie, Theodor, Suseno, Sandy
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Selectivity Control in the Palladium-catalyzed Cross-coupling of Alkyl Nucleophiles [PDF]
, 2016 Site-selectivity remains a major challenge in metal-catalyzed C–H bond functionalization. Most existing strategies rely on the introduction of a directing group or on the intrinsic reactivity of the substrate.
Baudoin, Olivier
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RhI/RhIII catalyst-controlled divergent aryl/heteroaryl C-H bond functionalization of picolinamides with alkynes [PDF]
, 2015 The ability to establish switchable site-selectivity through catalyst control in the direct functionalization of molecules that contain distinct C-H bonds remains a demanding challenge that would enable the construction of diverse scaffolds from the same
Alonso, Inés +5 more
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Iridium-Catalyzed Silylation of Unactivated C-H Bonds. [PDF]
, 2019 The functionalization of primary C-H bonds has been a longstanding challenge in catalysis. Our group has developed a series of silylations of primary C-H bonds that occur with site selectivity and diastereoselectivity resulting from an approach to run ...
Hartwig, John F, Romero, Erik A
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