Results 101 to 110 of about 459,122 (273)

Microenvironmental Modulation for Therapeutic Efficacy of Extracellular Vesicles

Advanced Science, EarlyView.
Recent studies highlighted the heterogeneity of EVs and the influence of microenvironmental signals on their therapeutic efficacy. This review offers a comprehensive overview of strategies and mechanisms to optimize the therapeutic efficacy of EVs through physical, biochemical, and mechanical modulation.
Bilu Xiang, Shiying Zhang, Irene Shuping Zhao, Xueqi Gan, Yang Zhang   +4 more
wiley   +1 more source

Precision‐Guided Stealth Missiles in Biomedicine: Biological Carrier‐Mediated Nanomedicine Hitchhiking Strategy

Advanced Science, EarlyView.
Diagram illustrating the binding methods of NPs and biological barriers. The biological carrier‐mediated nanomedicine hitchhiking strategy (BCM‐NHS) utilizes two distinct techniques: the surface‐based “Backpack” method, which relies on ligand‐receptor binding, covalent conjugation, and non‐covalent binding, and the encapsulated “Trojan horse” approach,
Yuyan Zhou, Xinyue Wang, Deyu Zhang, Hanxiao Cui, Xiaorong Tian, Wei Du, Zhenghui Yang, Dongling Wan, Zhiwei Qiu, Chao Liu, Zhicheng Yang, Lizhihong Zhang, Qiusheng Yang, Xuefeng Xu, Wenhao Li, Dong Wang, Haojie Huang, Wencheng Wu   +17 more
wiley   +1 more source

Complex regulatory network encompassing the Csr, c‐di‐GMP and motility systems of Salmonella Typhimurium [PDF]

, 2009
Kristina Jonas, Adrianne N. Edwards, Irfan Ahmad, Tony Romeo, Ute Römling, Öjar Melefors   +5 more
openalex   +1 more source

How Shallow and Deep Defects Drive Carrier Dynamics in Tin‐Iodide Perovskites

Advanced Energy Materials, EarlyView.
This study investigates complex carrier dynamics in tin‐based perovskite films using transient absorption spectroscopy (TAS) across a broad spectral and temporal range. It identifies two deep electron trap states – surface Sn(IV) defects and tin interstitials – while also revealing shallow traps that repopulate band edges within picoseconds.
Antonella Treglia, Andrea Olivati, Valentino Romano, Andrea Iudica, Giuseppe Maria Paternò, Isabella Poli, Annamaria Petrozza   +6 more
wiley   +1 more source

Prevention of quality characteristic decline in freeze‐thawed cultured large yellow croaker (Larimichthys crocea) using flammulina velutipes polysaccharide

Food Science &Nutrition, Volume 11, Issue 1, Page 181-190, January 2023., 2023
Our project aims to reveal the cryoprotective effect of flammulina velutipes polysaccharide (FVP) on the quality characteristics in freeze‐thawed cultured large yellow croaker. The differences were compared with conventional commercial cryoprotectant in combination with muscle quality, body color, and flavor.
Yuzhuo Shi, Yao Zheng, Baoguo Li, Xu Yang, Quanyou Guo, Anqi Liu   +5 more
wiley   +1 more source

c-di-GMP Turn-Over in Clostridium difficile Is Controlled by a Plethora of Diguanylate Cyclases and Phosphodiesterases [PDF]

, 2011
Éric Bordeleau, Louis‐Charles Fortier, François Malouin, Vincent Burrus   +3 more
openalex   +1 more source

Cell Membrane‐Coated Lipid Nanoparticles for Drug Delivery

Aggregate, EarlyView.
This review highlights recent progress in cell membrane‐coated lipid nanoparticles (CMC‐LNPs), focusing on their design, preparation methods, functional integration, and biomedical applications. It discusses various types of LNPs and coating strategies, characterization techniques, therapeutic functions, and applications.
Moataz B. Zewail, Guangze Yang, Yilong Fan, Yue Hui, Chun‐Xia Zhao, Yun Liu   +5 more
wiley   +1 more source

MicroRNA binding site variation is enriched in psychiatric disorders

Human Mutation, Volume 43, Issue 12, Page 2153-2169, December 2022., 2022
Abstract Psychiatric disorders have a polygenic architecture, often associated with dozens or hundreds of independent genomic loci. Most associated loci impact noncoding regions of the genome, suggesting that the majority of disease heritability originates from the disruption of regulatory sequences.
Michael P. Geaghan, William R. Reay, Murray J. Cairns   +2 more
wiley   +1 more source

Structure–property relationships of reduced graphene oxide membranes intercalated with polycyclic aromatics

AIChE Journal, EarlyView.
Abstract Graphene oxide (GO) membranes intercalated with various organic moieties have shown excellent potential for a range of water processing applications. However, microstructure–functional property relationships in these structurally disordered membranes are not well understood.
Muskan Sonker, Kaung Su Khin Zaw, Hazel P. Dhruve, Mahsa Abbaszadeh, Madeline P. Garell, Michael B. Salerno, Marta C. Hatzell, Meisha L. Shofner, Sankar Nair   +8 more
wiley   +1 more source

Regulation of development by c-di-GMP in Myxococcus xanthus

, 2019
Bei Myxococcus xanthus handelt es sich um ein Modellorganismus zur Untersuchung des soziale Verhaltens und der Zelldifferenzierung von Bakterien. Induziert durch Nährstoffmangel, starten die M.xanthus Zellen ein Entwicklungsprogramm, welches zur Bildung von Sporen gefüllten Fruchtkörpern und peripheren stäbchenförmigen Zellen außerhalb dieser ...
openaire   +3 more sources