Undirected, Homogeneous C–H Bond Functionalization: Challenges and Opportunities [PDF]
ACS Central Science, 2016 The functionalization of C-H bonds has created new approaches to preparing organic molecules by enabling new strategic "disconnections" during the planning of a synthetic route. Such functionalizations also have created the ability to derivatize complex molecules by modifying one or more of the many C-H bonds.
John F. Hartwig, Matthew A. Larsen
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Recent Advances in Regioselective C–H Bond Functionalization of Free Phenols [PDF]
Molecules, 2023 Phenols are important readily available synthetic building blocks and starting materials for organic synthetic transformations, which are widely found in agrochemicals, pharmaceuticals, and functional materials.
Yanan Li +3 more
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C–H Bond Functionalization of Amines: A Graphical Overview of Diverse Methods [PDF]
SynOpen, 2021 This Graphical Review provides a concise overview of the manifold and mechanistically diverse methods that enable the functionalization of sp3 C–H bonds in amines and their derivatives.
Subhradeep Dutta +4 more
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Synthesis of Benzo[4,5]thiazolo[2,3-c][1,2,4]triazole Derivatives via C-H Bond Functionalization of Disulfide Intermediates [PDF]
Molecules, 2022 Many nitrogen- and sulfur-containing heterocyclic compounds exhibit biological activity. Among these heterocycles are benzo[4,5]thiazolo[2,3-c][1,2,4]triazoles for which two main synthetic approaches exist.
Luis G. Ardón-Muñoz +1 more
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Site-Selective C─H Bond Functionalization of Sugars. [PDF]
Angew Chem Int Ed EnglAbstractNon‐typical C‐functionalized sugars represent a prominent yet hardly accessible class of biologically‐active compounds. The available synthetic methodologies toward such sugar derivatives suffer either from an extensive use of protecting groups, requiring long and laborious synthetic manipulations, or from limited predictability and ...
Stepanova EV +4 more
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C–H bond functionalization: recent discoveries and future directions [PDF]
Beilstein Journal of Organic Chemistry, 2023 Indranil Chatterjee
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In-situ noncovalent interaction of ammonium ion enabled C–H bond functionalization of polyethylene glycols [PDF]
Nature CommunicationsThe noncovalent interactions of ammonium ion with multidentate oxygen-based host has never been reported as a reacting center in catalytic reactions. In this work, we report a reactivity enhancement process enabled by non-covalent interaction of ammonium
Zongnan Zhang +9 more
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Transition-metal-free electrochemical-induced active C(sp3)-H functionalization
Green Chemistry Letters and Reviews, 2023 Direct C–H bond functionalization is the most effective technique to construct C–X (X = C, N, O, S, etc.), which could simplify the conventional synthesis methods.
Xiaolong Ma +4 more
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Green Synthesis and Catalysis, 2023 Transition-metal-catalyzed C–H bond functionalization has attracted tremendous attention as an increasingly important protocol for the construction of C–C and C–X bonds.
Jian Zhang +5 more
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C–H bond functionalization reactions enabled by photobiocatalytic cascades
Green Synthesis and Catalysis, 2021 Light may participate in biocatalytic processes either by direct light-induced biocatalysis or by cascading light-induced chemical reactions with biocatalytic ones, which are acknowledged as photocatalysis.
Yuanying Li +3 more
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