Results 11 to 20 of about 43,345 (260)
Molecules, 2021 Rollover cyclometalation constitutes a particular case of cyclometallation reaction. This reaction occurs when a chelated heterocyclic ligand loses its bidentate coordination mode and undergoes an internal rotation, after which a remote C–H bond is ...
Antonio Zucca, Maria I. Pilo
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Co(III) Intermediates in Cobalt-Catalyzed, Bidentate Chelation Assisted C(sp2)-H Functionalizations
Inorganics, 2023 The C-H bond activation and functionalization is a powerful tool that provides efficient access to various organic molecules. The cobalt-catalyzed oxidative C-H bond activation and functionalization has earned enormous interest over the past two decades.
Aleksandrs Cizikovs, Liene Grigorjeva
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Frontiers in Chemistry, 2021 Selectively activating the distal inactive C-H bond for functionalization is one of the on-going challenge in organic synthetic chemistry. In recent years, benefiting from the development of selective synthesis methods, novel methodologies not only make ...
Huang Junrong +11 more
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C−H Bond Functionalization under Electrochemical Flow Conditions
The Chemical Record, 2022 AbstractElectrochemical C−H functionalization is a rapidly growing area of interest in organic synthesis. To achieve maximum atom economy, the flow electrolysis process is more sustainable. This allows shorter reaction times, safer working environments, and better selectivities.
Tamlal Pokhrel +4 more
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Transition Metal-Catalyzed Remote C–H Bond Functionalization of Cyclic Amines
SynOpen, 2022 C–H bond functionalization is one of the most effective strategies for the rapid synthesis of cyclic amines containing substituents in the ring, which are core structures of many bioactive molecules. It is, however, much more challenging to perform this
Weijie Chen, Xiaoyu Yang, Xi Cao
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Tuning Benzylic C−H Functionalization of (Thio)xanthenes with Electrochemistry
Molecules, 2023 Here, we report a tunable electrochemical benzylic C−H functionalization of (thio)xanthenes with terminal alkynes and nitriles in the absence of any catalyst or external chemical oxidant.
Changji Wang +4 more
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Strategies to transform remote C(sp3)-H bonds of amino acid derivatives
Tetrahedron Chem, 2022 Amino acids and peptides play an important role in nature as well as in the pharmaceutical industry. Therefore, transformation of amino acids and peptides into their unnatural derivatives via step and atom economical ways is highly demanding. Although, a
Supreeta Sen +2 more
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Coumarins Synthesis and Transformation via C–H Bond Activation—A Review
Inorganics, 2022 For several decades, coumarins have attracted considerable attention due to the fact of their application in diverse fields such as medical science and biomedical research as well as several industrial branches.
Katarzyna Szwaczko
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A Simple Access to γ‐ and ε‐Keto Arenes via Enzymatic Divergent C─H Bond Oxyfunctionalization
Advanced Science, 2023 Performing divergent C─H bond functionalization on molecules with multiple reaction sites is a significant challenge in organic chemistry. Biocatalytic oxyfunctionalization reactions of these compounds to the corresponding ketones/aldehydes are typically
Huanhuan Li +6 more
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Nature Communications, 2022 Methods to functionalize inert C–H bonds are a critical focus of synthetic organic chemistry. In this work the authors use computations and experiments to uncover the mechanisms of palladium-catalysed C–H lactonizations in aromatic carboxylic acids, and ...
Li-Ping Xu +4 more
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