Results 1 to 10 of about 69,600 (248)
C-Type Lectin-Like Receptors: Head or Tail in Cell Death Immunity [PDF]
Frontiers in Immunology, 2020 C-type lectin-like receptors (CLRs) represent a family of transmembrane pattern recognition receptors, expressed primarily by myeloid cells. They recognize not only pathogen moieties for host defense, but also modified self-antigens such as damage ...
Marion Drouin +3 more
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C-Type Lectin-Like Receptors As Emerging Orchestrators of Sterile Inflammation Represent Potential Therapeutic Targets [PDF]
Frontiers in Immunology, 2018 Over the last decade, C-type lectin-like receptors (CTLRs), expressed mostly by myeloid cells, have gained increasing attention for their role in the fine tuning of both innate and adaptive immunity.
Elise Chiffoleau +3 more
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The diverse roles of C-type lectin-like receptors in immunity [PDF]
Frontiers in Immunology, 2023 Our understanding of the C-type lectin-like receptors (CTLRs) and their functions in immunity have continued to expand from their initial roles in pathogen recognition.
Michal Scur +3 more
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The protective effect of inflammatory monocytes during systemic C. albicans infection is dependent on collaboration between C-type lectin-like receptors. [PDF]
PLoS Pathogens, 2019 Invasive candidiasis, mainly caused by Candida albicans, is a serious healthcare problem with high mortality rates, particularly in immunocompromised patients. Innate immune cells express pathogen recognition receptors (PRRs) including C-type lectin-like
Aiysha Thompson +11 more
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Key thermally dimorphic fungal pathogens: shaping host immunity
Open Biology, 2022 Exposure to fungal pathogens from the environment is inevitable and with the number of at-risk populations increasing, the prevalence of invasive fungal infection is on the rise. An interesting group of fungal organisms known as thermally dimorphic fungi
Maxine A. Höft +2 more
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Innate Immune Sensing of Viruses and Its Consequences for the Central Nervous System
Viruses, 2021 Viral infections remain a global public health concern and cause a severe societal and economic burden. At the organismal level, the innate immune system is essential for the detection of viruses and constitutes the first line of defense.
Hina Singh, Jeffrey Koury, Marcus Kaul
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The Role of Lectin Receptors and Their Ligands in Controlling Allergic Inflammation
Frontiers in Immunology, 2021 More than fifty c-type lectin receptors (CLR) are known and have been identified so far. Moreover, we know the group of galectins and sialic acid-binding immunoglobulin-type lectins that also belong to the carbohydrate-binding receptors of the immune ...
Karin Peters, Marcus Peters
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Frontiers in Immunology, 2022 Molting is one of the most important biological processes of crustacean species, and a number of molecular mechanisms facilitate this complex procedure. However, the understanding of the immune mechanisms underlying crustacean molting cycle remains very ...
Meimei Liu +6 more
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Extensive Phenotype of Human Inflammatory Monocyte-Derived Dendritic Cells
Cells, 2021 Inflammatory monocyte-derived dendritic cells (Mo-DCs) have been described in several chronic inflammatory disorders, such as rheumatoid arthritis (RA), and are suspected to play a detrimental role by fueling inflammation and skewing adaptive immune ...
Frédéric Coutant +2 more
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Pharmaceutics, 2022 New-generation vaccines, formulated with subunits or nucleic acids, are less immunogenic than classical vaccines formulated with live-attenuated or inactivated pathogens.
Diego A. Díaz-Dinamarca +6 more
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