Results 31 to 40 of about 69,600 (248)
Innate immunity to Candida albicans
Japanese Dental Science Review, 2015 Candida albicans is not a pathogen in healthy individuals, but can cause severe systemic candidiasis in immunocompromised patients. C. albicans has various virulence factors and activates the innate immune system. Specifically, C.
Yusuke Kiyoura, Riyoko Tamai
doaj +1 more source
The effect of herbal medicine in innate immunity to Candida albicans
Frontiers in Immunology, 2023 Candida albicans (C. albicans) is an opportunistic pathogenic fungus that often causes mucosal and systemic infections. Several pattern recognition receptors (PRRs), such as Toll-like receptors (TLRs) and C-type lectin receptors (CLRs), have been ...
Meng-Yuan Bao +8 more
doaj +1 more source
C-type lectin receptors in skin immunity: Emerging new role for CLEC12B
Advances in Biomedical and Health Sciences, 2022 C-type lectin receptors (CLRs) are a superfamily of transmembrane proteins, which consist of one or several C-type lectin-like domains and intracellular signaling motifs, such as immunoreceptor tyrosine-based activation motif (ITAM) or immunoreceptor ...
Lauriane Blot +2 more
doaj +1 more source
Sweet Tooth, a Novel Receptor Protein-tyrosine Kinase with C-type Lectin-like Extracellular Domains [PDF]
Journal of Biological Chemistry, 2000 A gene encoding a novel type of receptor protein-tyrosine kinase was identified in Hydra vulgaris. The extracellular portion of this receptor (which we have named Sweet Tooth) contains four C-type lectin-like domains (CTLDs). Comparison of the sequences of these domains with the sequences of the carbohydrate recognition domains of various vertebrate C ...
J C, Reidling, M A, Miller, R E, Steele
openaire +2 more sources
Influenza–Host Interplay and Strategies for Universal Vaccine Development
Vaccines, 2020 Influenza is an annual epidemic and an occasional pandemic caused by pathogens that are responsible for infectious respiratory disease. Humans are highly susceptible to the infection mediated by influenza A viruses (IAV).
Hye Suk Hwang +2 more
doaj +1 more source
Nature Communications, 2023 Dimerization of C-type lectin receptors (CLRs) or Toll-like receptors (TLRs) can alter their ligand binding ability, thereby modulating immune responses. However, the possibilities and roles of dimerization between CLRs and TLRs remain unclear.
Fan Li +4 more
doaj +1 more source
Molecular recognition of paired receptors in the immune system
Frontiers in Microbiology, 2012 Cell surface receptors are responsible for regulating cellular function on the front line, the cell membrane. Interestingly, accumulating evidence clearly reveals that the members of cell surface receptor families have very similar extracellular ligand ...
Kimiko eKuroki +4 more
doaj +1 more source
Diagnostics, 2023 The scoring systems for disseminated intravascular coagulation (DIC) criteria require several adequate cutoff values, vary, and are complicated. Accordingly, a simpler and quicker diagnostic method for DIC is needed. Under such circumstances, soluble C-type lectin-like receptor 2 (sCLEC-2) received attention as a biomarker for platelet activation ...
Akitaka Yamamoto +10 more
openaire +3 more sources
PATTERN RECOGNITION RECEPTORS AND THEIR ROLE IN IMMUNOPATHOGENESIS OF PNEUMONIA (LITERATURE REVIEW)
Медицинская иммунология, 2019 Non-specific binding of antigens is provided by the so-called pattern recognition receptors (PRR). PRR can be located on the cell membrane, in the cytosol and in soluble form in the blood serum.
Maxim Olegovich Zolotov +2 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source