Signaling C-type lectin receptors in antimycobacterial immunity. [PDF]
PLoS Pathogens, 2017 Introduction The mammalian innate immune system is composed of phagocytes such as macrophages and dendritic cells that serve as the first line of defense against microbial infections. These cells express various pattern recognition receptors (PRRs) that
Mohlopheni J Marakalala, Hlumani Ndlovu
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A Proposal for Nomenclature in Myeloid C-Type Lectin Receptors [PDF]
Frontiers in Immunology, 2019 Myeloid C-type lectin receptors (CLRs) comprise a family of receptors expressed by immune myeloid cells that share homologous C-type lectin domains.
Carlos del Fresno +2 more
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MCL and mincle: C-type lectin receptors that sense damaged self and pathogen associated molecular patterns [PDF]
Frontiers in Immunology, 2014 MCL (macrophage C-type lectin) and mincle (macrophage inducible C-type lectin) comprise part of an extensive repertoire of pattern recognition receptors with the ability to sense damage associated and pathogen associated molecular patterns.
Mark B Richardson, Spencer J Williams
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The Interaction of Human Pathogenic Fungi With C-Type Lectin Receptors [PDF]
Frontiers in Immunology, 2018 Fungi, usually present as commensals, are a major cause of opportunistic infections in immunocompromised patients. Such infections, if not diagnosed or treated properly, can prove fatal.
Surabhi Goyal +5 more
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Targeting C-type Lectin Receptors for Cancer Immunity [PDF]
Frontiers in Immunology, 2015 C-type lectin receptors (CLRs) are a large family of soluble and trans-membrane pattern recognition receptors that are widely and primarily expressed on myeloid cells.
Huimin eYan +6 more
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Secondary Immune Surveillance via upregulation of C-type lectin receptors [PDF]
npj Gut and LiverC-type lectin receptors (CLRs) are a family of pattern recognition receptors that sense diverse microbial and damage-associated molecular patterns. Many CLRs, like Mincle and Dectin-3, are upregulated by TLR4 signaling.
Farhin Patel +4 more
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Differing Expression and Potential Immunological Role of C-Type Lectin Receptors of Two Different Chicken Breeds against Low Pathogenic H9N2 Avian Influenza Virus [PDF]
PathogensDiverse immune responses in different chicken lines can result in varying clinical consequences following avian influenza virus (AIV) infection. We compared two widely used layer breeds, Lohmann Brown (LB) and Lohmann White (LW), to examine virus ...
Sungsu Youk +2 more
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Quantitative Expression of C-Type Lectin Receptors in Humans and Mice [PDF]
International Journal of Molecular Sciences, 2012 C-type lectin receptors, their adaptor molecules and S-type lectins (galectins) are involved in the recognition of glycosylated self-antigens and pathogens.
Lech, Maciej +12 more
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C-type lectin receptors and RIG-I-like receptors: new points on the oncogenomics map
Cancer Management and Research, 2012 Anton G Kutikhin, Arseniy E YuzhalinDepartment of Epidemiology, Kemerovo State Medical Academy, Kemerovo, Russian FederationAbstract: The group of pattern recognition receptors includes families of Toll-like receptors, NOD-like receptors, C-type lectin ...
Yuzhalin AE, Kutikhin AG
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The diverse roles of C-type lectin-like receptors in immunity
Frontiers in Immunology, 2023 Our understanding of the C-type lectin-like receptors (CTLRs) and their functions in immunity have continued to expand from their initial roles in pathogen recognition.
Michal Scur +3 more
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