Results 11 to 20 of about 85,647 (228)
Targeting C-type Lectin Receptors for Cancer Immunity [PDF]
Frontiers in Immunology, 2015 C-type lectin receptors (CLRs) are a large family of soluble and trans-membrane pattern recognition receptors that are widely and primarily expressed on myeloid cells.
Huimin eYan +6 more
doaj +5 more sources
A Proposal for Nomenclature in Myeloid C-Type Lectin Receptors [PDF]
Frontiers in Immunology, 2019 Myeloid C-type lectin receptors (CLRs) comprise a family of receptors expressed by immune myeloid cells that share homologous C-type lectin domains.
Carlos del Fresno +2 more
doaj +6 more sources
The diverse roles of C-type lectin-like receptors in immunity
Frontiers in Immunology, 2023 Our understanding of the C-type lectin-like receptors (CTLRs) and their functions in immunity have continued to expand from their initial roles in pathogen recognition.
Michal Scur +3 more
doaj +5 more sources
Signaling C-type lectin receptors in antimycobacterial immunity. [PDF]
PLoS Pathogens, 2017 The mammalian innate immune system is composed of phagocytes such as macrophages and dendritic cells that serve as the first line of defense against microbial infections. These cells express various pattern recognition receptors (PRRs) that recognize specific pathogen-associated molecular patterns (PAMPs) on the surface of or inside microorganisms [1].
Mohlopheni J Marakalala, Hlumani Ndlovu
doaj +6 more sources
Secondary Immune Surveillance via upregulation of C-type lectin receptors [PDF]
npj Gut and LiverC-type lectin receptors (CLRs) are a family of pattern recognition receptors that sense diverse microbial and damage-associated molecular patterns. Many CLRs, like Mincle and Dectin-3, are upregulated by TLR4 signaling.
Farhin Patel +4 more
doaj +2 more sources
Differing Expression and Potential Immunological Role of C-Type Lectin Receptors of Two Different Chicken Breeds against Low Pathogenic H9N2 Avian Influenza Virus [PDF]
PathogensDiverse immune responses in different chicken lines can result in varying clinical consequences following avian influenza virus (AIV) infection. We compared two widely used layer breeds, Lohmann Brown (LB) and Lohmann White (LW), to examine virus ...
Sungsu Youk +2 more
doaj +2 more sources
Frontiers in Immunology, 2014 MCL (macrophage C-type lectin) and mincle (macrophage inducible C-type lectin) comprise part of an extensive repertoire of pattern recognition receptors with the ability to sense damage associated and pathogen associated molecular patterns.
Mark B Richardson, Spencer J Williams
doaj +3 more sources
The Interaction of Human Pathogenic Fungi With C-Type Lectin Receptors [PDF]
Frontiers in Immunology, 2018 Fungi, usually present as commensals, are a major cause of opportunistic infections in immunocompromised patients. Such infections, if not diagnosed or treated properly, can prove fatal.
Surabhi Goyal +5 more
doaj +2 more sources
C-Type Lectin-Like Receptors: Head or Tail in Cell Death Immunity
Frontiers in Immunology, 2020 C-type lectin-like receptors (CLRs) represent a family of transmembrane pattern recognition receptors, expressed primarily by myeloid cells. They recognize not only pathogen moieties for host defense, but also modified self-antigens such as damage ...
Marion Drouin +3 more
doaj +3 more sources
C-type lectin receptors in skin immunity: Emerging new role for CLEC12B
Advances in Biomedical and Health Sciences, 2022 C-type lectin receptors (CLRs) are a superfamily of transmembrane proteins, which consist of one or several C-type lectin-like domains and intracellular signaling motifs, such as immunoreceptor tyrosine-based activation motif (ITAM) or immunoreceptor ...
Lauriane Blot +2 more
doaj +2 more sources