Results 41 to 50 of about 84,931 (265)

C-Type Lectin Receptors [PDF]

Immunology of the Skin, 2015
Kanazawa N.
europepmc   +3 more sources

Differential roles for the adapters Gads and LAT in platelet activation by GPVI and CLEC-2 [PDF]

, 2008
Background: The adapter proteins SLP-76 and LAT have been shown to play critical roles in the activation of PLCc2 in platelets downstream of GPVI/FcRc and the C-type lectin receptor CLEC-2.
Pearce, AC, Watson, Steve P, Watson, Steve P., Eble, JA, Pearce, Andrew C., Pearce, A C, Hughes, C E, McGlade, Jane, Eble, Johannes A., Auger, Jocelyn; id_orcid, McGlade, J, Auger, Jocelyn M., Watson, Steve; id_orcid, Eble, J A, Pearce, Andrew C, Auger, J M, Watson, S P, Hughes, Craig, Hughes, C.E, Hughes, Craig E.   +19 more
core   +1 more source

C‐type lectin‐like receptors on myeloid cells

Annals of Medicine, 2006
Host defence against pathogens requires the recognition of conserved microbial molecules, or 'pathogen-associated molecular patterns' (PAMPs), by their receptors termed 'pattern recognition receptors' (PRRs), represented most notably by toll-like receptors (TLRs) and C-type lectins.
Elwira, Pyz, Andrew S J, Marshall, Siamon, Gordon, Gordon D, Brown   +3 more
openaire   +2 more sources

BACL is a novel brain-associated, non-NKC-encoded mammalian C-type lectin-like receptor of the CLEC2 family

, 2013
Natural Killer Gene Complex (NKC)–encoded C-type lectin-like receptors (CTLRs) are expressed on various immune cells including T cells, NK cells and myeloid cells and thereby contribute to the orchestration of cellular immune responses.
Mittelbronn, Michel Guy André, Michel Mittelbronn, Olga Lysenko (420632), Alexander Steinle (254716), Schulte, Dorothea, Lysenko, Olga, Dorothea Schulte, Steinle, Alexander, Alexander Steinle, Dorothea Schulte (420633), Olga Lysenko, Michel Mittelbronn (307400)   +11 more
core   +1 more source

Comparative transcriptomics reveals the immune dynamics during the molting cycle of swimming crab Portunus trituberculatus

Frontiers in Immunology, 2022
Molting is one of the most important biological processes of crustacean species, and a number of molecular mechanisms facilitate this complex procedure. However, the understanding of the immune mechanisms underlying crustacean molting cycle remains very ...
Meimei Liu, Meimei Liu, Hongwei Ni, Xiaokang Zhang, Qiufeng Sun, Xugan Wu, Jie He   +6 more
doaj   +1 more source

Towards defining the role of glycans as hardware in information storage and transfer: Basic principles, experimental approaches and recent progress [PDF]

, 2001
The term `code' in biological information transfer appears to be tightly and hitherto exclusively connected with the genetic code based on nucleotides and translated into functional activities via proteins.
Jiménez-Barbero, J., Romero, A., Gabius, Hans-Joachim, Siebert, H.-C., Solís, Dolores, Kaltner, H., Lieth, Claus-Wilhelm von der   +6 more
core   +1 more source

cDNA Cloning and Expression Analysis of Pattern Recognition Proteins from the Chinese Oak Silkmoth, Antheraea pernyi

Insects, 2012
Pattern recognition receptors play an important role in insect immune defense. We cloned the β-1,3-glucan recognition protein, lectin-5 and C-type lectin 1 genes of Antheraea pernyi and examined the expression profiles of immune-stimulated pupae.
Wenli Li, Suyun Fang, Yuan Li, Fengjuan Li, Olle Terenius   +4 more
doaj   +1 more source

Glycomimetic ligands block the interaction of SARS-CoV-2 spike protein with C-type lectin co-receptors [PDF]

, 2022
The C-type lectin receptors DC-SIGN and L-SIGN bind to glycans on the SARS-CoV-2 spike glycoprotein and promote trans-infection of ACE2-expressing cells.
Delaunay C., Thepaut M., Fieschi F., Bernardi A., Pollastri S.   +4 more
core   +1 more source

Inhibitory C-type lectin receptors in myeloid cells

Immunology Letters, 2011
C-type lectin receptors encoded by the natural killer gene complex play critical roles in enabling NK cell discrimination between self and non-self. In recent years, additional genes at this locus have been identified with patterns of expression that extend to cells of the myeloid lineage where many of the encoded inhibitory receptors have equally ...
Redelinghuys, Pierre, Brown, Gordon D
openaire   +3 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source