Results 21 to 30 of about 84,931 (265)

Snake C-type lectin-like proteins and platelet receptors

Pathophysiology of Haemostasis and Thrombosis, 2006
Snake venoms are complex mixtures of biologically active proteins and peptides. Many affect haemostasis by activating or inhibiting coagulant factors or platelets, or by disrupting endothelium. Snake venom components are classified into various families,
Clemetson, Kenneth John, Lu, Qiumin, Clemetson, Jeannine   +2 more
core   +4 more sources

Immunobiology of C-Type Lectin Receptors

, 2013
C-type lectin receptors (CLRs) that signal via the kinase Syk are an important class of pattern recognition receptors in the innate immune system. They recognize pathogen- and host-derived danger signals, and are best known for their role in antifungal ...
Roth, Susanne;Thomas, Christina;Ruland, Jürgen;Hartmann, G.;Wagner, H.
core   +2 more sources

C-type lectin receptors in skin immunity: Emerging new role for CLEC12B

Advances in Biomedical and Health Sciences, 2022
C-type lectin receptors (CLRs) are a superfamily of transmembrane proteins, which consist of one or several C-type lectin-like domains and intracellular signaling motifs, such as immunoreceptor tyrosine-based activation motif (ITAM) or immunoreceptor ...
Lauriane Blot, Thierry Passeron, Meri K Tulic   +2 more
doaj   +2 more sources

Myeloid C-Type Lectin Receptors in Viral Recognition and Antiviral Immunity [PDF]

Viruses, 2017
Recognition of viral glycans by pattern recognition receptors (PRRs) in innate immunity contributes to antiviral immune responses. C-type lectin receptors (CLRs) are PRRs capable of sensing glycans present in viral pathogens to activate antiviral immune ...
João T. Monteiro, Bernd Lepenies
doaj   +2 more sources

NOD1/2 and the C-Type Lectin Receptors Dectin-1 and Mincle Synergistically Enhance Proinflammatory Reactions Both In Vitro and In Vivo [PDF]

Journal of Inflammation Research, 2020
Amir I Tukhvatulin, Alina S Dzharullaeva, Alina S Erokhova, Dmitry V Scheblyakov, Boris S Naroditsky, Alexander L Gintsburg, Denis Y Logunov N. F. Gamaleya National Research Center for Epidemiology and Microbiology, Moscow, RussiaCorrespondence: Amir I ...
Tukhvatulin AI, Dzharullaeva AS, Erokhova AS, Scheblyakov DV, Naroditsky BS, Gintsburg AL, Logunov DY   +6 more
doaj   +2 more sources

Helicobacter pylori metabolites exacerbate gastritis through C-type lectin receptors. [PDF]

J Exp Med, 2021
Helicobacter pylori causes gastritis, which has been attributed to the development of H. pylori-specific T cells during infection. However, the mechanism underlying innate immune detection leading to the priming of T cells is not fully understood, as H ...
Nagata M, Toyonaga K, Ishikawa E, Haji S, Okahashi N, Takahashi M, Izumi Y, Imamura A, Takato K, Ishida H, Nagai S, Illarionov P, Stocker BL, Timmer MSM, Smith DGM, Williams SJ, Bamba T, Miyamoto T, Arita M, Appelmelk BJ, Yamasaki S.   +20 more
europepmc   +2 more sources

Paired C-type lectin receptors mediate specific recognition of divergent oomycete pathogens in C. elegans

Cell Reports
Summary: Innate immune responses can be triggered upon detection of pathogen- or damage-associated molecular patterns by host receptors that are often present on the surface of immune cells.
Kenneth Liu, Manish Grover, Franziska Trusch, Christina Vagena-Pantoula, Domenica Ippolito, Michalis Barkoulas   +5 more
doaj   +2 more sources

T Cell Antifungal Immunity and the Role of C-Type Lectin Receptors

Trends in Immunology, 2020
Ivy M Dambuza, Fabian Salazar, Gordon D Brown   +2 more
exaly   +2 more sources

The Role of Lectin Receptors and Their Ligands in Controlling Allergic Inflammation

Frontiers in Immunology, 2021
More than fifty c-type lectin receptors (CLR) are known and have been identified so far. Moreover, we know the group of galectins and sialic acid-binding immunoglobulin-type lectins that also belong to the carbohydrate-binding receptors of the immune ...
Karin Peters, Marcus Peters
doaj   +1 more source

C-type Lectin Receptors for Tumor Eradication: Future Directions [PDF]

Cancers, 2011
Dendritic cells are key regulators in directing immune responses and therefore are under extensive research for the induction of anti-tumor responses. DCs express a large array of receptors by which they scan their surroundings for recognition and uptake of pathogens.
Streng-Ouwehand, Ingeborg, Unger, Wendy W J, Van Kooyk, Yvette   +2 more
openaire   +4 more sources